In-Vitro Fertilization in Israel

InVitro Fertilization (IVF) in Israel

Many couples are now facing issues in getting pregnant. These issues may be for a very wide variety of reasons; it could be any family’s genetic problems, it could be because of long term exposure to some dangerous chemicals and so on and so forth. But there is a way that the chances of getting pregnant for women can be increased, one such way is to get the IVF Treatment in Israel. In order to know how this treatment can increase the chances of women getting pregnant, we should first understand how IVF actually works. IVF is an acronym for the In Vitro Fertilization procedure. The name is derived from the words "in vitro" which in English translate to the phrase "in the glass." It is referred to as such because of the way that it is carried out. The babies that have been conceived by this procedure are known as test tube babies. It is a pretty much simple procedure.

Treatment and Cost

60

Total Days
In Country

2 No. Travelers

1 Day in Hospital

59 Days Outside Hospital

Treatment cost starts from

USD 8000

Hospitals

About the IVF (In Vitro Fertilization)

The natural process of fertilization involves the conjugation of an egg and sperm inside the woman’s body. In-vitro-fertilization (IVF) is the procedure that involves the conception of an egg outside the body in a laboratory.  IVF comes under assisted reproductive technology (ART) that involves the use of advanced medical technology to help with pregnancy in the woman.

Which conditions may need IVF support?

  • Blocked Fallopian tubes
  • Endometriosis
  • Advanced age of a woman
  • Decreased sperm count
  • Failure of the treatment with fertility drugs

Types of IVF treatment

The different types of treatments available for IVF are:

  • Natural cycle IVF procedure: In this treatment, the fertility drugs are not administered. The egg released during the normal monthly cycle is collected and then fertilized.
  • Mild stimulation IVF procedure: The lower dose fertility drugs are administered and then the eggs are collected and fertilized.
  • In vitro maturation (IVM): The immature ovaries are collected and then allowed to mature in the laboratory.
  • Embryo transfer: The fertilized embryos are taken and transferred to the mother’s womb.
  • Blastocyst transfer: The embryos are cultured in the laboratory until blastocyst stage and then transferred to the mother’s womb.

IVF with Laser Assisted Hatching

Assisted hatching is a technique used in IVF where a gap or a hole is created on the outer shell of the embryo called zona pellucida before transferring the embryo into the mother’s womb. Before the implantation of the embryo, the developing embryo should “hatch” out of its outer shell (zona pellucida).

Sometimes the embryo is thick, which decreases its ability to hatch on its own. Making a hole or thinning the outer layer may help the embryos to hatch, which increases the chances of pregnancy. Pregnancy cannot occur unless the embryo hatches. Thus, assisted hatching IVF success rates are higher than simple IVF success rates.

Because of the use of additional technology, IVF with laser assisted hatching cost is higher than just IVF cost.

IVF with laser assisted hatching is recommended when:

  • The embryos do not have sufficient energy and nutrients to complete the hatching process
  • The woman is older than 37 years as they are more likely to have thick zona pellucida due to increased levels of follicle stimulating hormones
  • The candidate has had repeated IVF failure
  • The quality of the embryo is poor and demonstrated slow cell division and excessive fragmentation

It is performed by using infrared 1.48-μm diode laser. The technique does not cause any blastocyte damage. Laser assisted hatching has several advantages such as minimal handling of the embryo,  fast delivery, and exact control over the drilling of the hole.

It is performed before transferring the embryo into the mother’s womb on day 3, 5, or 6 after fertilization. An opening in the zona pellucida is created by drilling it with acidified tyrode’s solution.

The embryo is held firmly using holding pipette and a microneedle is applied on the area of zona pellucida. The microneedle is preloaded with Tyrode’s acid using mouth-controlled suction before each micromanipulation.

The acid is expelled over a small area of zona pellucida until it is breached. Suction is applied immediately after the breach of zona pellucida to prevent excess acid entering the embryo. The patients should be provided with antibiotics after implanting the embryo to reduce the risk of infections. 

IVF with Egg Donation

This procedure Is exactly the same as the usual IVF procedure with a difference that the egg used for fertilization comes from a different candidate than the one undergoing IVF. This procedure involves a process known as female egg donation in which a suitable candidate donates an egg for successful fertilization with the retrieved sperms.

The egg donation procedure is similar to how the eggs are retrieved from the womb of the future mother. The only difference is that during egg donation process, the ovaries of the donor are stimulated prior to the collection of suitable number of eggs from the ovaries. All the remaining stems in the donor egg IVF process are similar to the rest of the IVF procedure.

IVF with egg donation is mostly performed in the case of women who have insufficient number of eggs or whose eggs are compromised with respect to quality. The IVF specialist advices the woman to opt for donor eggs in case they believe that there are minimal chances of IVF success because of poor quality of her own eggs.

IVF with ICSI

Intracytoplasmatic sperm injection (ICSI) is an IVF variation in which the sperm is directly injected into the egg for fertilization. The resulting fertilized egg is placed in uterus of the woman. It is the most successful infertility treatment used to treat sperm-related conception problems in couples.

ICSI procedure does not require the sperm to penetrate the layers of the egg. It is highly useful to treat infertility problems in couples who suffer because the male partner’s sperms are either not able to get into the egg or are unable to fertilize the egg even when they are able to get through it.

During IVF with ICSI procedure, the eggs are extracted and held in one place with the help of a glass tool. A single sperm is injected into each egg using a small glass tube. The eggs are cultured and checked for fertilization overnight. The fully fertilized eggs are selected. A few fertilized eggs selected are placed in the uterus with the help of a catheter. The leftover embryos are preserved for future use.

While in simple IVF, the eggs and sperms are mixed together and allowed to fertilize naturally, in ICSI, a sperm is forced into the sperm for fertilization.

ICSI success rates largely depends on the quality of sperms used for fertilization. Overall, the success rate of ICSI is greater than any other technique used as a variation in the IVF procedure.

IVF with ICSI and Donor Sperms

IVF with ICSI is also performed when the sperms come from a suitable donor and not from the male partner of the female undergoing IVF procedure. ICSI IVF treatment is the same when conducted with donor sperms as it is with sperms that come from the male partner.

ICSI treatment involves the injection of a single sperm directly into the egg from the female partner or a donor. In the case of ICSI with donor sperms, a semen sample from a suitable donor is retrieved. The sperm sample is processed and viable and good quality sperms are extracted from for further procedure.

Next, the entire ICSI procedure is conducted in a similar manner. ICSI success rates are the same whether the sperm comes from a donor or the actual male partner. ICSI treatment cost is separate from the cost of IVF.

 

IVF with ICSI and Optical Spindle View

Optical spindle view is a specialized technique used at the time of IVF and ICSI. This technique helps the fertility specialists view the division of cells carefully to ensure that the entire process goes on smoothly.

The optical spindle view technique is used after the fusion of the eggs and the sperms is complete using ICSI as a part of the IVF procedure. The use of this technique helps ensure that the ICSI procedure is successful and that no DNA damage taken place around the site of injection of the sperm.

 

IVF with ICSI and Testicular Biopsy

Sometimes during IVF and ICSI, the fertility specialist may order a testicular biopsy to assess testicular function in the male partner before using his sperms. During testicular biopsy procedure, a small sample of tissue from just one or both the testicles is removed and examined under a microscope. The specialist confirms whether the male partner is fertile or not and accordingly donor sperms are arranged for IVF and ICSI.

 

How is IVF (In Vitro Fertilization) performed?

The steps through which IVF procedure occurs are:

Step 1: Over-stimulation of ovulation

Stimulation of the ovaries occurs with the administration of fertility drugs. The natural process involves the production of one egg per month, but the fertility drugs hyperstimulate the ovaries to produce more number of drugs.

Step 2: Retrieval of eggs

Removal of the eggs from the woman’s body is done through a minor surgery called follicular aspiration surgery. Pain medications are given to the woman and with the help of ultrasound, a thin needle attached to the suction pump is inserted into the vagina. The needle is directed towards the follicles containing eggs and suctions the fluid and the eggs.

Step 3: Insemination

The inactive cells from the semen are removed. The ovum and the sperms are incubated in the ratio of 1:75,000.

Step 4: Fertilization

The sperm enters the egg and fertilization takes place. If the sperm is found to be weak, then Intra-cytoplasmic sperm injection (ICSI) is performed which involves direct injection of sperm into the ovum.

Step 6: Culture of the embryo

After fertilization, the egg divides forming an embryo. The embryo rapidly divides within five days after fertilization.

Genetic diagnosis is performed after 3-4 days of fertilization to rule out the genetic disorders.

Step7: Transfer of the embryo

The embryos are transferred into the mother’s womb after 3-5 days of fertilization. This transfer is done with the help of a thin tube containing embryos. The tube is inserted through the vagina, cervix, and to the womb. Pregnancy is resulted if the embryo starts growing.

Recovery from IVF (In Vitro Fertilization)

Care to be taken after the procedure

  • You can perform your daily living activities from the next day.
  • Continue to take Progesterone pills for 8 to 12 weeks as decrease in progesterone levels may cause miscarriage.

If you have experience symptoms such as fever, pelvic pain, bleeding, and blood in urine, consult your physician immediately.

Patient Stories

Frequently Asked Questions

Why choose IVF and fertility treatments in Israel?

Israel is a very well developed country. It is not considered as a third world country but rather a country that is developing very rapidly. In a country that is developing as fast as Israel, the medical facilities are considered to be very good and modern. Many of the world’s leading doctors are in Israel currently.

What is the average cost of IVF in Israel?

The average cost of IVF in Israel will mostly depend on how many times you might have to have the IVF procedure done. But, never the less, average cost of IVF in Israel for each cycle of the IVF treatment could range between (USD 6000-USD 7000) six thousand dollars to about seven thousand dollars. This is still very less than when compared to the United States of America.

What is the process of IVF Treatment in Israel?

The process of IVF Treatment in Israel is not very complicated. It involves taking the fresh eggs from the female and fresh sperm from the male and then trying to fertilize them artificially. The fused egg and sperm are then monitored and implanted back in the womb of the woman.

How successful are IVF Treatments in Israel?

IVF success rate in Israel is very high compared to many other countries in the same region. This can be because of the fact that the medical facilities in Israel are much better than many other countries in the vicinity of Israel.

Which are the best IVF Clinics in Israel?

Some of the best IVF clinic in Israel include:

  • Herzliya Medical Center – This is one of the oldest hospitals in Israel with a dedicated IVF treatment place. It is a private hospital which was opened in the year of 1987. The facilities here are state of the art and are better than many other hospitals in other surrounding countries. It is located in the city of Herzliya in Israel.

  • IVF Clinic – Elisha Hospital – This is another very popular place for IVF treatments in Israel. They have very modern medical equipment as well as very good staff as well as good doctors on call that can assist you with all your needs. They have served hundreds of overseas patients and are well aware of the problems that foreigners can face in Israel. It is located in the city of Haifa.

  • Hadassah medical center – This is again a very old medical center that is present in Israel, located in Jerusalem; they see many foreign patients for treatment. Not only limited to IVF, but they also have very specialized doctors for various other wings of medicine as well. The staff are top-ranked and are very caring. All of the professions that work here are certified and have their background verified.

Which are the best cities for IVF Treatment in Israel?

Some of the best cities in Israel for the In vitro fertilization treatment in Israel are the most popular ones that tourists often visit. This can be probably because of the fact that medical tourism is a very big industry in the country of Israel. The most common and best cities in Israel are Haifa, Herzliya, the capital city of Jerusalem, the famous Tel Aviv, the port city of Eilat and so on. These cities have very good access by flights and also some by ships. That is another reason why medical tourists prefer to travel to these parts of Israel.

What is the health care infrastructure of Israel / Why should opt for Israel as a destination for your medical treatment?
Israel is one of the most developed countries in the world which has been rightly praised for the healthcare benefits it offers. Unlike historical times, Israel has upgraded and advanced itself to keep at par with the progression in the medical field and has thus been capable of providing the best of the best benefits to not only the native citizens but for tourists from all across the world. The reason why thousands of people prefer Israel over other countries is because of the high affordability of the medical facilities. The healthcare benefits of the hospitals and the clinics are competent with the major countries which means their services are uncompromised even though the packages can be availed at approximately 65% affordable rates.
What are the conditions of the hospitals in Israel? Are they JCI certified. What is the quality of the support staff in the hospitals?
Even though Israel is counted among one of the most affordable countries for medical treatments, the country houses best hospitals and clinics, which are teamed yo with professional physicians and surgeons as well as advanced medical equipment. Due to the quality of the treatment available, a number of hospitals and clinics in Israel have earned due JCI certification. Hence, some of the most popular hospitals in Israel which have attained JCI certification are:
  • Sheba Medical Center
  • Sourasky Medical Center
  • Rabin Medical Center
  • Rambam Medical Center
  • Assuta Hospital

Not only the doctors, the hospitals in Israel follow a strict protocol while selecting medical staffs, which is why, the quality of even the support staffs remain incomparable. The support staffs are also trained to handle emergency situations as well as critical cases with umpteenth care so as to ensure complete healthcare to the candidate undergoing minor to major procedures.

Are the doctors/surgeons in Israel of the best quality?
The doctors and surgeons in Israel are globally recognized for their excellent skills which has also garnered them with awards from reputed medical universities. A high number of complex and terminal cases have been successfully treated by the medical professionals working in the country. More than the progressing technology, the doctors are accredited for the impressive treatments in the United States of America, which is why, every year the USA records some of the highest number of medical tourists from various corners of the world.
What is the process for obtaining medical visa in Israel?
Visas for medical reasons are arranged by the sponsors directly through the government portal. However, the candidate should go through the procedure listed on the government portal so as to keep the documents and necessary photocopies, to be submitted, ready. In some cases, the candidate may also have to obtain a fresh permit from the Embassy mentioning the details and attaching the requirements to be followed. However, the documents needed for obtaining medical visa are:
  • Confirmation page of successfully filled visa application form
  • Visa fee paid and a photocopy of the receipt obtained for the same
  • Two passport size recent photographs not older than six months
  • Birth certificate, residential proof, employment proof, if any.
  • Civil status proof of the candidate
  • Minors require to provide signed consent of the parents or the guardians responsible
  • Medical certificate signed by the treating medical professional, mentioning clearly the cause of travel
  • Acceptance letter by the doctor being referred to, also stating the estimated time of stay required.
What support services does MediGence provide in Israel?
MediGence ensures a hassle-free medical travelling experience in Israel. Right from the beginning of the journey to the end, MediGence assists the candidates and the family with utmost care thereby making the stay as comfortable as it can be. Hence, here is a list of services provided for candidate satisfaction:
  • Visa Assistance
  • Free airport to hospital transfer
  • On-Ground Support
  • Teleconsultations
  • Accommodation Assistance
  • Rehabilitation and recovery services
Which are the best cities in Israel for medical treatment?
Israel is brimming with historic cities that have graced mankind with beautiful architecture. However, the country has also upgraded itself in terms of medical facilities. This, some of the best cities in Israel which are ideal for availing medical treatment are:
  • Ramat Gan
  • Beer Sheva
  • Tel Aviv
  • Haifa

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