Bone Marrow Transplant in India

Bone marrow transplant in India

Medical tourism in India is emerging as a top-class destination for people seeking quality and affordable medical care. The government of India has been promoting the medical tourism industry. The aim to make it one of the most wanted destinations for getting some high-quality medical treatments with the use of the latest medical technology and world-class infrastructure. Most of the oncologists and A bone marrow transplant is performed in persons whose marrow is not healthy enough to function correctly. This transplant procedure is performed to treat diseases like:

  • Leukemia
  • Multiple myelomas
  • Certain diseases like aplastic anemia, sickle anemia or thalassemia
  • Certain kind of immunodeficiency diseases
Treatment and Cost

20

Total Days
In Country

2 No. Travelers

2 Day in Hospital

18 Days Outside Hospital

Treatment cost starts from

USD 18000

Hospitals

About the Bone Marrow Transplant

Stem cell transplant is one modern technology that is undergoing rapid improvements. It is said these days that instead of investing in various life insurance policies that are making the rounds in the market, to secure the future and precious life of your child go for stem cell technologies. This can later cure him or her from any life threatening terminal disease like cancer. Stem cell transplant has been used in recent times as a cure for cancer, but the technique is different from the stem cell bank that is maintained these days for new born.

 

Who needs a stem cell transplant?

The bone marrow which is part of the bones is responsible for making blood cells. It is soft and spongy tissue lodged inside the bone having hematopoietic stem cells. These cells either turn into bone marrow cells or can turn into any other kinds of cells or the blood cells. But there are certain forms of cancers that can keep these cells from developing normally.

A patient is recommended to get a blood as well as bone marrow stem cell transplant if they are in a condition which prevents the body from producing new healthy blood cells. Some of the conditions and diseases that prevent the bone marrow from doing so are given below:

  • Cancers like Myeloma, breast cancer, leukemia, Lymphoma may require stem cell transplant
  • Blood diseases which may require are sickle cell anemia, aplastic anemia and thalassemia
  • There are immune deficiency diseases like the congenital neutropenia, severe combined immunodeficiency syndrome, chronic granulomatous disease may demand a stem cell transplant.

The oncologist or hematologist shall decide for a stem cell transplant for a patient depending upon overall age and health, severity of the diseases and other treatment possibilities.

 

What is a stem cell transplant?

So the stem cell transplant is a kind of treatment to treat blood disorders or any types of cancer. Even blood diseases are also treated with transplants. Previously patients had to undergo a bone marrow transplant due to the fact that stem cells are collected from the bone marrow. But today stem cells get collected from the blood. And for this particular reason they are now called stem cell transplants. Nowadays stem cell therapies are used to combat hair loss and many other aesthetic related issues.

Some of the different types of stem cell treatments available are discussed below

Autologous transplant: These kinds of transplants are known as auto transplant. This kind of transplant has the scope  of very high dose chemotherapy paired with autologous stem cell rescue. In this process usually the doctors treat the cancel and then make use of the stem cells from the patient itself. From the blood, stem cells are collected and the health care team then freezes it. These cells are usually placed back in the blood after thawing them in the frozen state post the chemotherapy. The cells take almost 24 hours to reach the bone marrow and start multiplying to give rise to healthy blood cells.

Allogenic transplantation: This is better known as an allo transplant medically. In this case stem cells are obtained from another individual. But this individual needs to be someone with whom the bone marrow of the patient matches. Due to presence of proteins in white blood cells called the human leukocyte antigens (HLA) it is important that bone marrow matching takes place. The most compatible stem cell donor will have the HLA matching with that of the patient.

But the process of matching can also give rise to a very severe condition named graft versus host disease or GVHD but then it is not very likely. In this kind of a disease the healthy cells obtained from transplantation will start attacking the cells of the patients. In such cases siblings are considered to be the best match. And if they are not available then some other close family member can also work. Once the donor is fixed then the patient starts receiving chemotherapy session with or without radiotherapy. The other person’s stem is then placed in a vein via a tube. These cells unlike the previous ones are not frozen so they can be given immediately after the completion of chemotherapy.

There can be two types of Allo transplantation depending upon the age, condition and the disease that is being addressed:

The first kind is ablative where high dose of chemotherapy is used and in the second kind milder doses of chemotherapy is employed.

When the assigned health care team is unable to find a matched adult donor then are other options that must be considered like the Umbilical cord blood transplant and these days cancer centers all around the globe make use of cord blood.

Parent child transplant and haplotype mismatched transplant: In these kinds of transplants which are commonly employed the match found is 50% instead of 100% and the donor can be a parent, child or brother and sister.

How is Bone Marrow Transplant performed?

The first step in bone marrow transplant is to reduce the tumour so that the stem cell transplant success rate is improved. The process of harvesting stem cells takes around three to four hours, depending on the number of stem cells collected. The entire process may take around three to five days to complete. Blood count is daily monitored during collection of stem cells to ensure that it does not go below the admissible levels in the donor, which may contribute to anaemia.

A catheter is placed in the donor’s arm during the actual stem cell transplant procedure. The catheter is connected to a special machine that separated stem cells from the blood. After extracting the stem cells, the remaining blood is infused back into the donor's body.

 

Stem Cell Harvesting Procedure

The stem cell concentration in the bone marrow is almost 10 to 100 times more than the levels found in peripheral blood. The hip bone is considered to have the greatest amount of marrow in the active state and a large number of stem cells can also be extracted from there.

The process of harvesting the stem cells from the bone marrow is carried out in an operating room. The donor is given either general anaesthesia, an epidural, or spinal anaesthesia.

The surgeon makes a number of punctures over the skin covering the pelvic bone. A special kind of needle attached to a syringe is then inserted through these punctures. The needle penetrates the bone marrow and blood is drawn out along with marrow through the syringe. The process is continued several times to ensure enough numbers of stem cells are collected as required for the transplant. The whole duration can last for a period of one to two hours. The amount of blood and marrow removed will vary according to the weight and concentration of stem cells in the marrow of the donor. At the end of this procedure, the surgeon covers the puncture region with pressure dressing and bandages. The collected cells are filtered to separate fat particles and fragments of bones. The donor is taken to the recovery room where the hospital team checks for signs of pain, bleeding or any other side effects of the procedure. The donor can leave the hospital in a few hours after his or her body has recovered. But in some cases, they may be required to stay overnight for better monitoring.

The hip area of the donor remains sore for a few days and it is important to take medicines as directed to relieve the pain. Until the blood cell counts increase, doctors may suggest iron supplements t to enhance the ability of the bone marrow to replenish blood cells.

 

Stem Cell Transplant Procedure

High dose of chemotherapy is given to the patient immediately after stem cell collection or can even be done at a later stage. Stem cells are injected into the bloodstream of the patient after the completion of high dose chemotherapy. These stem cells travel all the way to bone marrow to start producing new blood cells, which is important as a number of healthy blood cells are lost during high dose chemotherapy.

Recovery from Bone Marrow Transplant

Until the bone marrow is in a position to make sufficient blood cells, the patient is at the risk of contracting infections and diseases. Therefore, the patient is kept in an isolation room following stem cell transplantation to protect him or her from contamination. The stay in isolation room lasts for over a week or until the level of blood cells is back to normal again.

Isolation is more important in the case of allogeneic stem cell transplant than autologous stem cell transplant. This is the reason why some hospitals do not prefer to keep a patient who has had an autologous transplant isolated.

During the recovery period, only one or two visitors are allowed to visit the patient. Those who are already ill should strictly avoid visiting the patient. There are a few hospital who conduct autologous stem cell transplant on an outpatient basis. However, the patient must come for follow-up 0vists regularly for monitoring of their health.

Patient Stories

Frequently Asked Questions

Why should you go for a bone marrow transplant in India

Bone marrow transplantation is a life-saving treatment for patients whose marrow isn’t functioning properly. The bone marrow may get damaged due to certain chronic diseases or infections and in some cases, due to ongoing cancer treatment. 

Bone marrow transplant in India is one of the most established forms of treatment offered to patients across several specialized BMT units and hospitals. One of the main reasons why patients should choose to go for bone marrow transplant in India is that this complex procedure is conducted with extreme care in world-class hospitals and a secure and sterile environment by experienced experts only.

Some of the reasons that make India one of the most preferred destinations for bone cells treatment in India include the following:

  • Ultra-modern infrastructure

  • Practically no waiting time

  • Experienced and internationally-trained medical experts

  • State-of-the-art bone marrow transplant laboratories

  • Readily available transfusion services

  • Fully equipped radiation oncology labs

  • Reasonable pricing

  • Availability of latest technology

  • English-speaking doctors and other staff in top hospitals

What are the best cities for bone marrow transplant in India

The best hospitals for bone marrow transplant in India have together performed numerous transplants so far with a high success rate. Some of these hospitals for BMT in India are located in the metropolitan cities, that is, the cities with the maximum population and the ones that are connected to all major countries through direct flights.

Some of the best bone marrow transplant centers in India are located in the most popular cities such as Delhi, Mumbai, Hyderabad, Bangalore, and Chennai. These cities have maximum concentration centers for Bone Marrow Transplantation in India.

The metropolitan cities in India have advanced infrastructure and facilities. These cities possess extensive transportation network, good quality and reasonable hotels, multicuisine restaurants, foreign exchange services, money transfer facilities such as Western Union, and other services and things. It is convenient for a traveler from any part of the world to stay in these cities and get medical treatment.

What is the cost of bone marrow transplant in India

Bone marrow transplant cost in India is one of the best in the world. This is the reason why so many patients from around the world, especially from the Middle Eastern countries, Mauritius, Nigeria, and other African countries, and South East Asia, travel to India to get it done.

It is available for a variety of conditions. For example, a bone marrow transplant for thalassemia in India is available across several multispecialty hospitals with state-of-the-art and specialized BMT units with all the facilities. Thalassemia bone marrow transplant cost in India starts from approximately $32000.

The exact bone marrow transplant cost in India depends on two main reasons – the type of BMT conducted and the type of condition to be treated. The average cost of bone marrow transplant in India for autologous transplant starts from approximately $18000. On the other hand, the cost of allogeneic transplant in India starts from approximately $28000. In certain cases, an allogeneic transplant may be recommended or conducted. Its cost is approximately $7000 in India.

Bone marrow transplantation cost in India depends on the condition. It is different for conditions such as lymphoma, leukemia, multiple myeloma, thalassemia, and so on. It also depends on the city where you get it done and the hospital. For example, bone marrow transplantation cost in Bangalore is different from that in Delhi or Mumbai, and so on.

What are the top hospitals and doctors for bone marrow transplant in India

Some of the best bone marrow transplant centers in India are located in Delhi, Mumbai, Bangalore, Hyderabad, and Chennai. These hospitals are equipped with the latest technology and world-class infrastructure and the onco-surgeons associated with these hospitals are extensively experienced and have attained global recognition.

Some of the best hospitals for bone marrow transplant in India include the following:
  • Indraprastha Apollo Hospital, New Delhi

  • BLK Superspecialty Hospital, New Delhi

  • Artemis Hospital, Gurugram

  • Sri Ram Chandra Medical Center, Chennai

  • Global Health City, Chennai

  • Narayana Hrudalaya, Bangalore

  • Aster Medcity, Kochi

  • Gleneagles Global Hospital, Chennai

  • Fortis Mulund, Mumbai

  • HCG Hospital, Bangalore

Some of the best doctors for bone marrow transplant in India include the following:
  • Dr. Amita Mahajan, Indraprastha Apollo Hospital, New Delhi

  • Dr. Dharma Chaudhary, BLK Superspecialty Hospital, New Delhi

  • Dr. Pravas Chandra Mishra, Max Hospital, New Delhi

  • Dr. Esha Kaul, Jaypee Hospital, Delhi NCR

  • Dr. Sarita Rani, Dharamshila Narayana Superspecialty Hospital, Delhi

  • Dr. P Anoop, Global Hospital, Bangalore

  • Dr. Rahul Naithani, Max Superspecialty Hospital, New Delhi

Is bone marrow transplant successful in India

The success rate of bone marrow transplant in India is one of the best in the world. This is one of the main reasons why the country draws so many patients for this procedure every year. The success rate of this procedure is estimated to be around 80 to 90 percent in India.

The high success rate of bone marrows transplant in India can be attributed to the high standards of care, preventive steps taken to prevent infections, sterile environment, excellent aftercare, and great monitoring. Also, the BMT specialists in India are highly experienced in dealing with different types of condition and the complications associated with the procedure.

The success rate, however, depends on several factors. For example, it depends on how well the body of the patient responds to the stem cells derived from his or her own body or a donor, the rate of rejection, the occurrence of any complications, need for extra medications, the effect on other organs, disease relapse status etc.

Which are the best hospitals for Bone Marrow Transplant in India?

1. Fortis Memorial Research Institute

The bone marrow transplant at Fortis Hospital, Gurugram is done at the Institute of Blood disorders and Bone marrow transplant. The institute has done more than 1000 bone marrow transplants with a high success rate. The hospital caters the patients from more than 36 countries. The treatment provided at the institute is according to the international protocol and guidelines. The institute is equipped for performing advanced bone marrow transplant surgery including the autologous and allogeneic bone marrow transplant. The bone marrow transplant team comprises of experienced hematologists and haemato-oncologists along with other experts and paramedical staff. The hospital has a 22 bedded transplant unit.

2. Venkateshwar Hospital

Venkateshwar hospital is a research-driven institute with advanced facilities for bone marrow transplantation. The bone marrow transplant department is an integral part of the Centre of Haemato-Medical Oncology and Bone Marrow Transplant.  The bone marrow transplant at Venkateshwar hospital is done in various hematological disorders. The hospital is equipped for performing various types of bone marrow transplant surgery including Peripheral Stem Cells, Allogenic & Autologous bone marrow transplant. The hospital also focusses on Haploidentical and Matched Unrelated Donor Transplant. To access the health of patients at a single point, the center is also equipped with a variety of diagnostic services including 3 Tesla MRI, PET-CT Scanning, Bone Scan, CT Scan & Blood Bank.

3. Max Smart Super Speciality Hospital

Max Smart Super Speciality hospital is anew and advanced hospital treating various medical conditions. The hospital has advanced facilities for performing bone marrow transplant surgery. The doctors at this hospital are experienced and provide world-class treatment and care. All types of bone marrow transplantation i.e. allogeneic and Autologous Bone Marrow/Stem Cell Transplantation in children and adults is performed at the hospital. The treatment provided is customized according to the need of the patient. The hospital has advanced imaging techniques for the best diagnosis. the equipment available includes 256 Slice CT Angio, Cath Labs with electrophysiology navigation, 3.0 Tesla digital broadband MRI, and a flat panel C-Arm detector.

4. Indraprastha Apollo Hospital

Indraprastha Apollo Hospital is known for performing bone marrow transplant surgery with a high success rate. The center has all the facilities required for performing a successful bone marrow transplant. The hospital performs all types of bone marrow transplants including the Allogenic & Autologous bone marrow transplant. The stem cell transplant at the Apollo hospital includes bone marrow transplantation, peripheral blood, and cord blood. The bone transplant is done at the hospitals to treat various conditions includingLeukemia, Lymphoma, Aplastic Anemia, Multiple Myeloma, Thalassemia, and various genetic disorders. The facilities available at Apollo hospital includestem cell collection, cryopreserving them after processing, and infusion.

5. Artemis Health Institute

The Bone marrow transplant is done at Artemis Hospital with a high success rate. Artemis Hospital is JCI accredited, and the team of bone marrow transplant surgery comprises of best doctors. The hospital has advanced and modern infrastructure. The paramedical staff including the nurses are extensively trained for post-surgical care. To reduce the risk of infections, the hospital is equipped with HEPA filters, and positive pressure rooms. The infection control policies are in place to avoid any chance of infection. The facilities available at the hospital include the blood bank, advanced imaging machines, hematology, microbiology, and histopathology lab services, and world-class Critical Care Units and Intensive Care Units.

What is the health care infrastructure of India / Why should opt for India as a destination for your medical treatment?
India is a large country with a rapidly expanding system of healthcare. Like many other countries, there are public and private hospitals in India. This also includes healthcare at three levels.
  • The primary level of healthcare includes Sub Centres and Primary Health Centres.
  • At the secondary level are District Hospitals and smaller Sub-District hospitals. These are the first referral units, mostly from the primary healthcare centres.
  • Finally, the top level of health care provided is the tertiary level, which consists of Medical Colleges and Specialized Hospitals.
Since India boasts of housing a large number of people, the requirement for good healthcare and treatment in India is always there. And this also means prompt delivery of the service. Most of the treatment in India has to be offered at reasonable costs to enable people of all classes to access it. Hence, you can be assured that this country will be a great destination for your medical treatment whichever hospital in India you wish to choose.
What are the conditions of the hospitals in India? Are they JCI certified? What is the quality of the support staff in the hospitals?
The Joint Commission International (JCI) is a global leader in health care accreditation. JCI accreditation is considered a gold standard in worldwide health care. It provides the most skilled and experienced healthcare professionals in the medical industry, as evaluators of the rigorous international standards in healthcare quality and patient safety.
Here are some JCI certified hospitals in India:
  • Fortis Escorts Health Institutes, Delhi
  • Columbia Asia Referral Hospital, Bangalore
  • Fortis Hospital, Bangalore
  • Apollo Hospital, Chennai
  • Sri Ramachandra Medical Center, Chennai
  • Ahalia Foundation Eye Hospital, Kerala
  • Rajagiri Hospital, Kochi
  • Asian Heart Institute, Mumbai
  • Fortis Hospital, Mumbai
  • Kokilaben Dhirubhai Ambani Hospital, Mumbai
  • SevenHills Hospitals, Mumbai
  • Apex Heart Institute (A Unit Of TCVS Pvt)
  • Apollo Gleneagles Hospitals, Kolkata.
  • Fortis Hospitals Ltd, Mulund, Mumbai
  • Narayana Multispeciality Hospital Jaipur (A Unit of Narayana Hrudayalaya Ltd.)
Hospitals in India are ever-changing to accommodate more people with up to date technology. Hospitals in India also attract patients from other countries because of their diverse range of services. Apart from allopathy and conventional treatment procedures, the government of India, along with the hospitals in India also promote alternative medical treatment options like Ayurveda, homeopathy, and yoga. All in all, you will find great options for any kind of treatment in India.
Are the doctors/surgeons in India of the best quality?
Doctors and surgeons in India have to get through examinations and continue to uphold the standard of education that is provided to them. Since doctors get exposure to various patients during their course, they are able to diagnose and treat a wide range of diseases and illnesses. Therefore, one can rely on the doctors of India for their medical services.
What is the process for obtaining a medical visa in India?
The e-Medical Visa for India is an online travel authorization for foreign nationals who wish to seek medical treatment in the country. A medical Indian visa allows the holder to enter the country 3 times.

The e-Medical visa is a short term visa granted for medical treatment reasons. This type of visa is only granted to the patient and not to their family members.

Foreign nationals can acquire an India e-Medical visa by filling in an online application form. This simple process can be done from the comfort of the traveler’s home or office, avoiding a trip to an embassy or consulate.

Applicants must submit their basic personal information, including their full name, nationality, and date of birth. They must also provide a contact email address and phone number as well as their passport details. Finally, some security questions must be answered.

The form is quick and easy to fill out. The approved India medical visa is then delivered to the applicant’s email address within a few business days.
What support services does MediGence provide in India?
MediGence enables you to plan and manage your medical decisions better. These are some of our services offered:
  • Expert Opinion
    We help you seek an Expert Opinion on your diagnosis and treatment from an experienced team of doctors at MediGence and specialists from a reputable hospital.
  • Hospital Recommendation
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  • 360-degree Hospital Review
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  • Doctor Validation and Communication
    We share a comprehensive profile of the treating doctor and also arrange a call to clear queries regarding treatment if needed.
  • Options to Choose From
    Based on your choice of destination and other preferences, we provide you multiple options with respect to hospitals and doctors to choose from.
  • 24X7 Patient Care Support
    A dedicated patient case manager stays in constant touch with you to help you at every step of the decision-making process and resolve queries that you may have.
  • Transparent Treatment Cost and Other Expenses
    We give a clear and accurate indication of the total cost of treatment including treatment, stay, meals, and other expenses.
  • Visa Assistance
    We provide and help prepare documentation for visa approval and coordinate with the embassy to expedite the visa process.
  • Accommodation Arrangements
    We propose to you a choice of accommodation based on your preference such as long stay, short stay, or luxury properties.
Which are the best cities in India for medical treatment?
India is a beautiful country spread across the vast expanse of the Asian subcontinent. Most of the metro cities have hospitals, in India, with varying levels of infrastructure. Depending on your need and medical service, you can visit your choice of city.
The capital of India is Delhi and has many renowned hospitals like the All India Institute of Medical Sciences, Max Super speciality Hospital Fortis Hospitals, etc.
Other cities offering effective medical care include Bangalore, Chennai, Mumbai, and Hyderabad. These cities come under some of the major metro cities of India.

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