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A bone marrow transplant is often referred to as a hematopoietic stem cell transplant, or simply a stem cell transplant. Leukemia, myeloma, lymphoma, and other blood and immune system disorders that damage the bone marrow can all be treated by transplantation. This is a procedure in which healthy cells are used to replace your bone marrow. You have the option of using a donor or your own body's replacement cells.
| Country | Cost | Local_currency |
|---|---|---|
| United Kingdom | USD 184000 | 145360 |
| Turkey | USD 30000 - 40000 | 904200 - 1205600 |
| Spain | USD 71000 - 157700 | 65320 - 145084 |
| United States | USD 471600 - 929600 | 471600 - 929600 |
| Singapore | USD 20000 - 60000 | 26800 - 80400 |
Dr. Shagufta Parveen is a Clinical researcher and medical writer with expertise in clinical pharmacology and pharmacotherapeutics. She holds a B.Pharm and Doctor of Pharmacy (Post-Baccalaureate) degree from Teerthanker Mahaveer University, Moradabad.
During her clinical stint at BLK-Max Super Speciality Hospital and Indraprastha Apollo Hospital, she gained hands-on experience in the Clinical Pharmacology Department. Combining scientific knowledge with strong medical writing skills, Dr. Shagufta develops evidence-based healthcare content, treatment guides, and patient education resources.
Her work focuses on simplifying complex medical concepts while maintaining scientific accuracy, helping readers better understand healthcare advancements and treatment options.
In addition to her writing expertise, she is actively involved in scientific research and has contributed to peer-reviewed publications.
Her research work is accessible through the following links:
https://scholar.google.com/citations?user=lMVK1eIAAAAJ&hl=en
https://carcinogenesis.com/index.php/JOC/article/view/870
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A bone marrow transplant is a process that involves harvesting cells for transplantation from the bone marrow which is the spongy tissue found in the cavities of certain bones such as the hip bones. It is also known as Stem Cell transplant. The bone marrow is rich in stem cells, which are capable of developing into various types of blood cells.
The main objective of bone marrow transplantation (BMT) is to transplant healthy bone marrow cells into a patient after the patient's unhealthy bone marrow has been treated to eliminate cancerous cells.
BMT has been used successfully in the treatment of the following diseases such as:
There are two main types of bone marrow transplants (BMT), also known as stem cell transplants, based on the source of the stem cells. These are:
Autologous BMT treatment is primarily performed for cancers like multiple myeloma, lymphoma, and a few solid tumors. It allows for administering high doses of chemotherapy, which helps the patient restore their healthy bone marrow cells. It is used if the disease is responsive to chemo and a patient's marrow is healthy enough to be harvested and used later.
An initial consultation with a haematologist or oncologist for BMT is warranted if you are diagnosed with a cancer treatable by autologous BMT and have failed conventional treatments or are at high risk of relapse. Otherwise, BMT should be considered if you have persistent symptoms or abnormal blood counts or at the suggestion of your treating oncology team.
Before the procedure begins, you will undergo evaluation for bloodwork and imaging, along with an assessment of organ function. The stem cells will be harvested from your blood via apheresis and stored. Also, depending on your condition, a central line will be placed. It may be recommended that you avoid any infections. Counselling and education before transplants are also part of the procedure.
First, high-dose chemotherapy will be given to kill cancer cells and bone marrow. Next, frozen autologous stem cells are thawed, infused into the bloodstream, travel to the bone marrow, and start regenerating normal blood cells in a sterile hospital environment.
The entire procedure, from stem cell collection to recovery, may continue for weeks. The patient is hospitalised for 2-3 weeks following the procedure and then monitored on an outpatient basis for several months.
The recovery process consists of immune reconstitution and takes several weeks to months. The patient requires watchful follow-up, especially concerning infection control and supportive care such as transfusions. The diet, activity, and hygiene of the patients are carefully observed. Fatigue will continue until it starts to fade away, while strength is returned slowly.
Success rates vary according to disease, but they are usually quite encouraging. Five-year survival rates may vary between 50 and 80%, depending on the type of cancer and the general health status.
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Bone marrow transplants (BMT), also known as hematopoietic stem cell transplants (HSCT), can be life-saving for patients whose bone marrow is not functioning to produce healthy blood cells.
