IVF (In Vitro Fertilization) cost in Singapore

IVF stands for in vitro fertilization. This is a highly advanced technology that helps childless couples conceive a baby successfully. This treatment is used as a treatment for both male and female infertility. During this treatment, an egg and a sperm are made to fuse in a Petri dish under laboratory conditions. The developing zygote is transferred to the womb of the mother at 8- or 16-celled stage, where further development takes place.

IVF Treatment in Singapore

In vitro fertilization in Singapore is conducted at some of the globally renowned hospitals. Thousands of infertile couples from across the world choose Singapore as their destination for IVF because of several reasons. First, the cost of treatment in the country and the cost of overall living are quite affordable. Secondly, the best hospitals for IVF treatment in Singapore are equipped with latest technology and equipment used to conduct this procedure. Moreover, this procedure is performed by a team of highly experienced and skilled IVF experts.

Treatment and Cost

30

Total Days
In Country

2 No. Travelers

0 Day in Hospital

30 Days Outside Hospital

Treatment cost starts from

USD 11200

Hospitals

About the IVF (In Vitro Fertilization)

The natural process of fertilization involves the conjugation of an egg and sperm inside the woman’s body. In-vitro-fertilization (IVF) is the procedure that involves the conception of an egg outside the body in a laboratory.  IVF comes under assisted reproductive technology (ART) that involves the use of advanced medical technology to help with pregnancy in the woman.

Which conditions may need IVF support?

  • Blocked Fallopian tubes
  • Endometriosis
  • Advanced age of a woman
  • Decreased sperm count
  • Failure of the treatment with fertility drugs

Types of IVF treatment

The different types of treatments available for IVF are:

  • Natural cycle IVF procedure: In this treatment, the fertility drugs are not administered. The egg released during the normal monthly cycle is collected and then fertilized.
  • Mild stimulation IVF procedure: The lower dose fertility drugs are administered and then the eggs are collected and fertilized.
  • In vitro maturation (IVM): The immature ovaries are collected and then allowed to mature in the laboratory.
  • Embryo transfer: The fertilized embryos are taken and transferred to the mother’s womb.
  • Blastocyst transfer: The embryos are cultured in the laboratory until blastocyst stage and then transferred to the mother’s womb.

IVF with Laser Assisted Hatching

Assisted hatching is a technique used in IVF where a gap or a hole is created on the outer shell of the embryo called zona pellucida before transferring the embryo into the mother’s womb. Before the implantation of the embryo, the developing embryo should “hatch” out of its outer shell (zona pellucida).

Sometimes the embryo is thick, which decreases its ability to hatch on its own. Making a hole or thinning the outer layer may help the embryos to hatch, which increases the chances of pregnancy. Pregnancy cannot occur unless the embryo hatches. Thus, assisted hatching IVF success rates are higher than simple IVF success rates.

Because of the use of additional technology, IVF with laser assisted hatching cost is higher than just IVF cost.

IVF with laser assisted hatching is recommended when:

  • The embryos do not have sufficient energy and nutrients to complete the hatching process
  • The woman is older than 37 years as they are more likely to have thick zona pellucida due to increased levels of follicle stimulating hormones
  • The candidate has had repeated IVF failure
  • The quality of the embryo is poor and demonstrated slow cell division and excessive fragmentation

It is performed by using infrared 1.48-μm diode laser. The technique does not cause any blastocyte damage. Laser assisted hatching has several advantages such as minimal handling of the embryo,  fast delivery, and exact control over the drilling of the hole.

It is performed before transferring the embryo into the mother’s womb on day 3, 5, or 6 after fertilization. An opening in the zona pellucida is created by drilling it with acidified tyrode’s solution.

The embryo is held firmly using holding pipette and a microneedle is applied on the area of zona pellucida. The microneedle is preloaded with Tyrode’s acid using mouth-controlled suction before each micromanipulation.

The acid is expelled over a small area of zona pellucida until it is breached. Suction is applied immediately after the breach of zona pellucida to prevent excess acid entering the embryo. The patients should be provided with antibiotics after implanting the embryo to reduce the risk of infections. 

IVF with Egg Donation

This procedure Is exactly the same as the usual IVF procedure with a difference that the egg used for fertilization comes from a different candidate than the one undergoing IVF. This procedure involves a process known as female egg donation in which a suitable candidate donates an egg for successful fertilization with the retrieved sperms.

The egg donation procedure is similar to how the eggs are retrieved from the womb of the future mother. The only difference is that during egg donation process, the ovaries of the donor are stimulated prior to the collection of suitable number of eggs from the ovaries. All the remaining stems in the donor egg IVF process are similar to the rest of the IVF procedure.

IVF with egg donation is mostly performed in the case of women who have insufficient number of eggs or whose eggs are compromised with respect to quality. The IVF specialist advices the woman to opt for donor eggs in case they believe that there are minimal chances of IVF success because of poor quality of her own eggs.

IVF with ICSI

Intracytoplasmatic sperm injection (ICSI) is an IVF variation in which the sperm is directly injected into the egg for fertilization. The resulting fertilized egg is placed in uterus of the woman. It is the most successful infertility treatment used to treat sperm-related conception problems in couples.

ICSI procedure does not require the sperm to penetrate the layers of the egg. It is highly useful to treat infertility problems in couples who suffer because the male partner’s sperms are either not able to get into the egg or are unable to fertilize the egg even when they are able to get through it.

During IVF with ICSI procedure, the eggs are extracted and held in one place with the help of a glass tool. A single sperm is injected into each egg using a small glass tube. The eggs are cultured and checked for fertilization overnight. The fully fertilized eggs are selected. A few fertilized eggs selected are placed in the uterus with the help of a catheter. The leftover embryos are preserved for future use.

While in simple IVF, the eggs and sperms are mixed together and allowed to fertilize naturally, in ICSI, a sperm is forced into the sperm for fertilization.

ICSI success rates largely depends on the quality of sperms used for fertilization. Overall, the success rate of ICSI is greater than any other technique used as a variation in the IVF procedure.

IVF with ICSI and Donor Sperms

IVF with ICSI is also performed when the sperms come from a suitable donor and not from the male partner of the female undergoing IVF procedure. ICSI IVF treatment is the same when conducted with donor sperms as it is with sperms that come from the male partner.

ICSI treatment involves the injection of a single sperm directly into the egg from the female partner or a donor. In the case of ICSI with donor sperms, a semen sample from a suitable donor is retrieved. The sperm sample is processed and viable and good quality sperms are extracted from for further procedure.

Next, the entire ICSI procedure is conducted in a similar manner. ICSI success rates are the same whether the sperm comes from a donor or the actual male partner. ICSI treatment cost is separate from the cost of IVF.

 

IVF with ICSI and Optical Spindle View

Optical spindle view is a specialized technique used at the time of IVF and ICSI. This technique helps the fertility specialists view the division of cells carefully to ensure that the entire process goes on smoothly.

The optical spindle view technique is used after the fusion of the eggs and the sperms is complete using ICSI as a part of the IVF procedure. The use of this technique helps ensure that the ICSI procedure is successful and that no DNA damage taken place around the site of injection of the sperm.

 

IVF with ICSI and Testicular Biopsy

Sometimes during IVF and ICSI, the fertility specialist may order a testicular biopsy to assess testicular function in the male partner before using his sperms. During testicular biopsy procedure, a small sample of tissue from just one or both the testicles is removed and examined under a microscope. The specialist confirms whether the male partner is fertile or not and accordingly donor sperms are arranged for IVF and ICSI.

 

How is IVF (In Vitro Fertilization) performed?

The steps through which IVF procedure occurs are:

Step 1: Over-stimulation of ovulation

Stimulation of the ovaries occurs with the administration of fertility drugs. The natural process involves the production of one egg per month, but the fertility drugs hyperstimulate the ovaries to produce more number of drugs.

Step 2: Retrieval of eggs

Removal of the eggs from the woman’s body is done through a minor surgery called follicular aspiration surgery. Pain medications are given to the woman and with the help of ultrasound, a thin needle attached to the suction pump is inserted into the vagina. The needle is directed towards the follicles containing eggs and suctions the fluid and the eggs.

Step 3: Insemination

The inactive cells from the semen are removed. The ovum and the sperms are incubated in the ratio of 1:75,000.

Step 4: Fertilization

The sperm enters the egg and fertilization takes place. If the sperm is found to be weak, then Intra-cytoplasmic sperm injection (ICSI) is performed which involves direct injection of sperm into the ovum.

Step 6: Culture of the embryo

After fertilization, the egg divides forming an embryo. The embryo rapidly divides within five days after fertilization.

Genetic diagnosis is performed after 3-4 days of fertilization to rule out the genetic disorders.

Step7: Transfer of the embryo

The embryos are transferred into the mother’s womb after 3-5 days of fertilization. This transfer is done with the help of a thin tube containing embryos. The tube is inserted through the vagina, cervix, and to the womb. Pregnancy is resulted if the embryo starts growing.

Recovery from IVF (In Vitro Fertilization)

Care to be taken after the procedure

  • You can perform your daily living activities from the next day.
  • Continue to take Progesterone pills for 8 to 12 weeks as decrease in progesterone levels may cause miscarriage.

If you have experience symptoms such as fever, pelvic pain, bleeding, and blood in urine, consult your physician immediately.

Patient Stories

Frequently Asked Questions

Why should you go for IVF in Singapore

Many couples struggling with infertility prefer to go to Singapore to get IVF treatment done. Singapore, as a medical tourism destination, is popular for its health care services and treatment facilities, and IVF is one of them.

There are many reasons why couples should choose to undergo IVF procedure in Singapore. Some of these reasons include the following:

  • Availability of all the latest assisted reproductive techniques

  • There are a number of clinics in Singapore with state-of-the-art embryology labs

  • It is highly accessible

  • The cost is comparable as compared to the Western countries such as the US

  • High standard of services and great professionalism

  • Availability of trained IVF specialists

What is the cost of IVF in Singapore

Even though IVF cost in Singapore is much more than the other popular medical tourism destinations, including Turkey, Thailand, and India, many couples still prefer to choose Singapore because of a greater sense of security and better treatment quality.

The IVF cost in Singapore starts at approximately $13000. It includes all the basic steps in an IVF cycle, including consultation, ovarian stimulation, egg retrieval, lab charges, and the cost of embryo transfer. The package does not usually including the pre-investigations conducted before the start of ovarian stimulation, the cost of medications prescribed after embryo transfer, and the expenses associated with any special technique such as intracytoplasmic sperm injection (ICSI) or the use of egg donor or sperm donor.

What are the top hospitals for IVF in Singapore

There are many clinics and hospitals that perform IVF procedure in Singapore. Some of the best IVF doctors in Singapore are associated with the JCI-certified hospitals in the country. A majority of them also have their independent clinics or may act as a visiting consultant across several hospitals.

Some of the hospitals with the best fertility doctors in Singapore include the following:

  • Mount Elizabeth Hospital

  • Mount Elizabeth Novena Hospital

  • Raffles Medical

  • Thompson Medical

  • Gleneagles Global Hospital

Is IVF in Singapore successful

IVF is a highly sensitive procedure, the success of which depends on a number of variables. It usually takes multiple cycles for couples to be able to finally conceive a baby.

The success rate of IVF in Singapore is between 40 to 60 percent. The best IVF doctors in Singapore are highly qualified, experienced, and skilled. It is recommended that one should only undergo IVF procedure in Singapore under the guidance of an experienced and qualified specialist.

However, the success of the IVF procedure depends on a number of other factors. For example, it depends on individual factors such as the quality of the egg and sperm, the health of the uterine wall for implantation, receptivity, the overall health status of the mother-to-be, and how well her body receives the embryo.

IVF is a tedious procedure that requires a lot of patience and preparation. The mother-to-be is expected to remain calm and stress-free during the entire procedure, failure of which may ultimately lead to the failure of the IVF cycle.

FAQ's Related to Singapore

What healthcare accreditation standards are followed in Singapore?

The hospitals in Singapore are all apprised and then given accredition by Joint Commission International, the premier accredition agency in the world. Joint Commission International or JCI makes sure that the hospitals in Singapore are keeping up standards of patient safety and healthcare quality. Any hospital in Singapore that has been apprised by and approved on Organisation management by the Joint Commission International is the one which is really sought after by all. It is only after stringent assessment measures that hospitals in Singapore are given the certification by the Joint Commission International.

Which are the popular multispecialty hospital groups in Singapore?

The popular multi specialty hospital groups in Singapore are as follows

  1. Mount Elizabeth Hospital
  2. Raffles Hospital
  3. National University Hospital
  4. Gleneagles Hospital
  5. Singapore General Hospital
  6. Changi General Hospital
  7. Johns Hopkins Singapore International Medical Centre
  8. Tan Tock Seng Hospital
  9. Parkway Hospitals Singapore

The popular multispecialty hospitals in Singapore give the best medical treatment and it is no wonder that these hospitals are truly international in the form of the diverse patient population that frequents them. The popular multispecialty hospitals in Singapore are known for their high quality of medical professionals in a wide variety of specialties. In the popular multispecialty hospitals in Singapore you get the best of medical treatment in short waiting times.

Why should I opt for healthcare in Singapore?

You must choose your healthcare in Singapore because of the excellent healthcare infrastructure that defines the Singaporean healthcare landscape. The hospitals and healthcare professionals in Singapore are well defined with the best of clinical outcomes and an all round care. The focus on the high levels of service is a reason that an increasing number of people are opting for healthcare in Singapore. The ease of travel and access to quality healthcare are the reasons that make Singapore an attractive medical tourism destination.

What is the quality of doctors in Singapore?

The doctors in Singapore are thorough professionals with immense practical knowledge of their area of specialisation. The emphasis of the doctors in Singapore is on precision and efficiency of treatment and these can be used to assess that the quality of doctors in Singapore is really good. As Singapore is a major international medical tourism destination, the doctors in Singapore have great international exposure which ensures that the quality of doctors in Singapore is very high. The quality of doctors in Singapore can be defined by the fact that they have been educated from the best of the institutions in the world and are very skilled in their work.

When traveling to Singapore for medical treatment, what essential documents do I need to carry along?

We bring to you the list of documents needed for your medical travel to Singapore:

  1. Medical Records and Reports describing your medical condition
  2. Communication from the hospital and/or the doctor that has referred you
  3. Passport
  4. Treatment Plan and Frequency of treatment
  5. Fit to travel confirmation
  6. To and Fro travel tickets
  7. Visa relevant to your visit as a medical traveller to Singapore
  8. Proof of financial means for travel and treatment
  9. Credit Card/Debit Card/Valid internet banking account in Singapore

While you are planning your journey to Singapore as a medical traveller, it is important that you create a checklist of the documents that you need to carry. The documents that you need to carry for your medical treatment to Singapore will be consisting of your financial standing, your travel related documents and the ones that are related to your medical condition. The travel documents that you are carrying with you should cover your requirements as a medical tourist which will make your treatment, stay and travel back as streamlined as possible.

What are the popular procedures available in Singapore?

The popular procedures available in Singapore are as follows.

  1. Dentistry
  2. Orthopedics
  3. Cardiology
  4. Cosmetic/Plastic Surgery
  5. Ophthalmology

Cardiology procedures have long been the forte of healthcare providers in Singapore owing to their expertise stemming from the best of education and training in performing these procedures. The Orthopaedic surgery procedures are synonymous with excellence as they are performed with precision and efficiency in the hospitals in Singapore. There are may popular cosmetic surgery procedures which are regularly done in clinics and hospitals in Singapore such as:

  1. Liposuction
  2. Rhinoplasty
  3. Face Lift
  4. Breast Augmentation
  5. Blepharoplasty
What are the other facilities provided by hospitals in Singapore?

It is the hospitals in Singapore that are giving a world class treatment to their patients and their loved ones accompanying them by providing several additional facilities. Some facilities provided by the hospital that will aid your travel and transfer process during your medical travel to Singapore are,

  1. Accommodation
  2. Flight Booking
  3. Airport Transfers
  4. Interpreter

The payment facilities available in the hospitals in Singapore are private payment gateways and the option of getting private insurance. Other facilities provided by hospitals in Singapore are health screening programmes, dietitians and presence of pharmacies in the hospitals.

What is the procedure for obtaining medical visa for Singapore?

It is important that you check the visa requirements for your country as Singapore is a country with relaxed visa norms for many countries. Please find below the required documents for a medical visa to Singapore:

  1. Passport with the required time validity
  2. Completed application form
  3. LOI or Letter of Introduction from a local contact in Singapore
  4. A recent passport size photograph
  5. Bio data page photocopy of the passport of the applicant
  6. Covering letter and forwarding letter

Please check the required visa fee from your country for Singapore medical visa. The medical visa processing time from Singapore is 5 working days and this excludes the day of visa submission (delays due to incomplete applications or during peak periods is not ruled out). Your original bank statements will be checked by the concerned officials in order to assess your financials so that your Singapore medical visa can be granted.