IVF stands for in vitro fertilization. This is a highly advanced technology that helps childless couples conceive a baby successfully. This treatment is used as a treatment for both male and female infertility. During this treatment, an egg and a sperm are made to fuse in a Petri dish under laboratory conditions. The developing zygote is transferred to the womb of the mother at 8- or 16-celled stage, where further development takes place.
In vitro fertilization in India is conducted at some of the globally renowned hospitals. Thousands of infertile couples from across the world choose India as their destination for IVF because of several reasons. First, the cost of treatment in the country and the cost of overall living are quite affordable. Secondly, the best hospitals for IVF treatment in India are equipped with the latest technology and equipment used to conduct this procedure. Moreover, this procedure is performed by a team of highly experienced and skilled IVF experts.
The natural process of fertilization involves the conjugation of an egg and sperm inside the woman’s body. In-vitro-fertilization (IVF) is the procedure that involves the conception of an egg outside the body in a laboratory. IVF comes under assisted reproductive technology (ART) that involves the use of advanced medical technology to help with pregnancy in the woman.
The different types of treatments available for IVF are:
Assisted hatching is a technique used in IVF where a gap or a hole is created on the outer shell of the embryo called zona pellucida before transferring the embryo into the mother’s womb. Before the implantation of the embryo, the developing embryo should “hatch” out of its outer shell (zona pellucida).
Sometimes the embryo is thick, which decreases its ability to hatch on its own. Making a hole or thinning the outer layer may help the embryos to hatch, which increases the chances of pregnancy. Pregnancy cannot occur unless the embryo hatches. Thus, assisted hatching IVF success rates are higher than simple IVF success rates.
Because of the use of additional technology, IVF with laser assisted hatching cost is higher than just IVF cost.
IVF with laser assisted hatching is recommended when:
It is performed by using
It is performed before transferring the embryo into the mother’s womb on day 3, 5, or 6 after fertilization. An opening in the zona pellucida is created by drilling it with acidified tyrode’s solution.
The embryo is held firmly using holding pipette and a microneedle is applied
The acid is expelled over a small area of zona pellucida until it is breached. Suction is applied immediately after the breach of zona pellucida to prevent excess
This procedure Is exactly the same as the usual IVF procedure with a difference that the egg used for fertilization comes from a different candidate than the one undergoing IVF. This procedure involves a process known as female egg donation in which a suitable candidate donates an egg for successful fertilization with the retrieved sperms.
The egg donation procedure is similar to how the eggs are retrieved from the womb of the future mother. The only difference is that during
IVF with egg donation is mostly performed in the case of women who have
Intracytoplasmatic sperm injection (ICSI) is an IVF variation in which the sperm is directly injected into the egg for fertilization. The resulting fertilized egg is placed in
ICSI procedure does not require the sperm to penetrate the layers of the egg. It is highly useful to treat infertility problems in couples who suffer because the male partner’s sperms are either not able to get into the egg or are unable to fertilize the egg even when they are able to get through it.
During IVF with ICSI procedure, the eggs are extracted and held in one place with the help of a glass tool. A single sperm is injected into each egg using a small glass tube. The eggs are cultured and checked for fertilization overnight. The fully fertilized eggs are selected. A few fertilized eggs selected are placed in the uterus with the help of a catheter. The leftover embryos are preserved for future use.
While in simple IVF, the eggs and sperms are mixed together and allowed to fertilize naturally, in ICSI, a sperm is forced into the sperm for fertilization.
ICSI success rates largely
IVF with ICSI is also performed when the sperms come from a suitable donor and not from the male partner of the female undergoing IVF procedure. ICSI IVF treatment is the same when conducted with donor sperms as it is with sperms that come from the male partner.
ICSI treatment involves the injection of a single sperm directly into the egg from the female partner or a donor. In the case of ICSI with donor sperms, a semen sample from a suitable donor is retrieved. The sperm sample is processed and viable and good quality sperms are extracted from for further procedure.
Next, the entire ICSI procedure is conducted in a similar manner. ICSI success rates are the same whether the sperm comes from a donor or the actual male partner. ICSI treatment cost is separate from the cost of IVF.
Optical spindle view is a specialized technique used at the time of IVF and ICSI. This technique helps the fertility specialists view the division of cells carefully to ensure that the entire process goes on smoothly.
The optical spindle view technique is used after the fusion of the eggs and the sperms
Sometimes during IVF and ICSI, the fertility specialist may order a testicular biopsy to assess testicular function in the male partner before using his sperms. During
Step 1: Over-stimulation of ovulation
Stimulation of the ovaries occurs with the administration of fertility drugs. The natural process involves the production of one egg per month, but the fertility drugs hyperstimulate the ovaries to produce more number of drugs.
Step 2: Retrieval of eggs
Removal of the eggs from the woman’s body is done through a minor surgery called follicular aspiration surgery. Pain medications are given to the woman and with the help of ultrasound, a thin needle attached to the suction pump is inserted into the vagina. The needle is directed towards the follicles containing eggs and suctions the fluid and the eggs.
Step 3: Insemination
The inactive cells from the semen are removed. The ovum and the sperms are incubated in the ratio of 1:75,000.
Step 4: Fertilization
The sperm enters the egg and fertilization takes place. If the sperm is found to be weak, then Intra-cytoplasmic sperm injection (ICSI) is performed which involves direct injection of sperm into the ovum.
Step 6: Culture of the embryo
After fertilization, the egg divides forming an embryo. The embryo rapidly divides within five days after fertilization.
Genetic diagnosis is performed after 3-4 days of fertilization to rule out the genetic disorders.
Step7: Transfer of the embryo
The embryos are transferred into the mother’s womb after 3-5 days of fertilization. This transfer is done with the help of a thin tube containing embryos. The tube is inserted through the vagina, cervix, and to the womb. Pregnancy is resulted if the embryo starts growing.
If you have experience symptoms such as fever, pelvic pain, bleeding, and blood in urine, consult your physician immediately.
IVF in India is one of the most popular procedures for which couples from abroad, especially from the Western, African, and Middle Eastern countries travel. It is a common procedure which is conducted at some of the best infertility hospitals and clinics in the country.
There are many reasons why one should travel to India for IVF procedure. Some of these reasons include the following:
India has some of the best IVF specialists in the world. A majority of the globally-renowned IVF specialists in India completed their specialization and training in assisted-reproductive technologies from abroad. They are known for their skills and experience.
The cost of IVF procedure in India is highly competitive in the world. It is one of the main reasons why childless couples from abroad the world flock to the country to get the procedure done.
The labs are the best IVF centers in India are well-maintained and possess the latest technology to conduct the procedure.
The IVF success rate in India is one of the best in the world, thanks to the experience of the specialists, the availability of the latest technology, and the quality if medications available.
Some of the best IVF centers in India are located in Tier-1 cities such as New Delhi, Pune, Bangalore, Chennai, Mumbai, and Hyderabad. Even though these cities possess the maximum concentration of clinics and hospitals that conduct IVF in India, that does not mean that centers in Tier-2 cities are bad.
The advantage of opting for IVF in India in Tier-1 cities is that these are very well-developed when it comes to the infrastructure and other facilities such as hotels, cabs, restaurants, and money exchange facility. Even from the security point of view, these cities are safe and the police patrolling is common in all important areas of these cities even during the night.
Local transportation is not an issue in these cities. Also, all metropolitan cities in India have an international and domestic airport that connects it to the rest of the world through direct or indirect flights.
There are more than 100 hospitals and clinics in India that offer IVF to people from within the country and abroad. All of these hospitals and clinics possess state-of-the-art laboratories, equipment, and facilities to conduct the procedure.
Some of the best IVF clinics in India are located in the following hospitals:
Max Hospital, New Delhi
Indraprastha Apollo Hospital, New Delhi
BLK Superspecialty Hospital, New Delhi
SevenHills Hospital, Mumbai
Global Health City, Chennai
Gleneagles Global Hospital, Mumbai
Aster Medcity, Kochi
Kohinoor Hospital, Mumbai
Manipal MEMG Hospital, Goa
Some of the best IVF specialists in India include the following:
IVF procedure cost in India starts from approximately $2800 per cycle at a good clinic or a hospital. It may go up as high as $5000 per cycle of IVF, depending on the choice of hospital or clinic, the location of the hospital, the experience of the doctor, and the success rates associated with the hospital and doctor.
The costing for one cycle of IVF usually includes up to five consultations during the process, monitoring ultrasounds (stimulation to pick up), ovulation induction injections (for ovulation stimulation), anaesthesia and anaesthetist fee (for ovum pick up only), short stay room rent, operation theatre (OT) charges, fees of the embryologist, surgeon’s fees, and OT and IVF consumables for ovum pick up, and embryo transfer.
IVF cost in India is one of the lowest in the world. It is a fairly expensive procedure in Western countries and other developed nations, including Australia, New Zealand, the US, and the UK.
The total IVF cost in India could be more, depending on the need for any additional procedures such as repeat IVF cycle, embryo freezing, egg retrieval using medications, intracytoplasmic sperm injection (ICSI), and egg freezing.
IVF success rate in India is one of the best in the world. Although there is no credible cumulative data available to exactly represent the success rates of IVF in India across different hospitals and clinics, it is believed to be somewhere around 60 to 70 percent.
The global average for the success rate of IVF is around 40 to 50 percent. Considering this ratio, the IVF success rate is still better. However, it greatly varies from one clinic to the other and the number of cases that they handle per month.
For example, a clinic may take up just one to two selected cases of IVF a month and may show a 100 percent success rate. On the other hand, the success rate is bound to be less in clinics and hospitals that take up 50 to 100 cases a month.
IVF is a very sensitive procedure, the success of which varies from one candidate to the other and depends on individual parameters and characteristics. For example, it depends on the age of the candidate, their overall health, stress levels, and individual body responses etc.
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