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IVF (In Vitro Fertilization) Treatment Cost in Spain

IVF (In Vitro Fertilization) cost in Spain varies between ESP 6292 to 7074 (USD 6840 to USD 7690)approx

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IVF (In vitro fertilization) treatment is one of the advanced approaches implemented by couples who are unable to conceive naturally. Difficulty in conceiving by intercourse may be due to several genetic or physiological anomaly. However, advanced measures in medical science have made it possible to conceive a healthy baby through artificial methods. The word, in vitro, means fertilization in a laboratory. The process had first been successful in the year 1977 and has henceforth been implemented all across the world.

What is IVF (In Vitro Fertilization)?

In the IVF (In Vitro Fertilization) treatment, ovum (eggs) from the mother and sperm from the father are collected and made to fertilize in a culture media, in the laboratory. The sperm and the ovum may also be collected from donors, in case one of the parents is unable to produce healthy gametes. After successful fertilization, the embryo is then transferred to the uterus of the mother, where it gets implanted on the endometrial lining. Multiple embryo transfer to the uterus may result in multiple pregnancies and result in the birth of more than one baby.

Top Clinics in Spain for IVF

  • Juaneda Fertility Center
  • Manzanera Medical Center
  • CERAM Clinic
  • Barcelona IVF
  • HC Marabella International Hospital
  • IREMA, Alicante

Cost of IVF in Spain

Spain offers competitive pricing for IVF with respect to other European countries. The cost of a single IVF with own eggs range around €4,000 – 8,000. Whereas the single IVF cycle carried with donor eggs ranges around €6,000 – 11,000.

The cost of frozen embryo transfers may cost around €1,500 – 2,000.

Factors Affecting the Cost of IVF in Spain

The cost of IVF treatment costs in Spain may vary from $10,000 to $15,000 per cycle. However, the cost thus mentioned does not include the price of medications required for the procedure. The cost of medication may vary from $1500 to $3000 and depends on the condition and requirement of the candidate. Besides, the key factors on which the cost of IVF treatment in Spain depend are:

  • Number of IVF cycles required for a successful pregnancy
  • The extent of treatment required
  • Type of medication required
  • Underlying, serious health issues, if any, should be monitored and treated
  • Healthcare facilities where the treatment is being sought from
  • Experience and proficiency of the medical practitioners involved
  • Involvement of a donor

Following is the list of cities and the associated costs for IVF (In Vitro Fertilization) in Spain

CityMinimum CostMaximum Cost
BarcelonaUSD 6840USD 7690
MadridUSD 6840USD 7660
MarbellaUSD 7090USD 7430

Country wise cost comparison for IVF (In Vitro Fertilization):

CountryCostLocal_currency
GreeceUSD 4540Greece 4177
IndiaUSD 3200India 266080
IsraelUSD 8000Israel 30400
LithuaniaUSD 4200Lithuania 3864
MalaysiaUSD 5000Malaysia 23550
MoroccoUSD 3000Morocco 30120
SpainUSD 6840Spain 6293
ThailandUSD 8000Thailand 285200
TunisiaUSD 6000Tunisia 18660
TurkeyUSD 3510Turkey 105791
United Arab EmiratesUSD 7000United Arab Emirates 25690

Treatment and Cost

30

Total Days
In Country
  • 0 Day in Hospital
  • 2 No. Travelers
  • 30 Days Outside Hospital

Treatment cost starts from

USD6840

Top selling packages for IVF (In Vitro Fertilization)

In Vitro Fertilization

Delhi, India

USD 4500 USD 5000

Verfifed

Additional Benefits
Complimentary Stay for 2 in a Hotel for 15 Nights
Free Room Upgrade from Economy to Private
Complimentary Video Consultation with the Specialist
Airport Transfers
City Tour for 2
Priority Appointment
Cancel Anytime with Full Refund
24*7 Patient Care & Support Services

MediGence is offering immense facilities for your medical journey such as:

  1. Complimentary Stay for 2 in a Hotel for 15 Nights
  2. Free Room Upgrade from Economy to Private
  3. Complimentary Video Consultation with the Specialist
  4. Airport Transfers
  5. City Tour for 2
  6. Priority Appointment
  7. Cancel Anytime with Full Refund
  8. 24*7 Patient Care & Support Services

Costing Details

We offer packages at reasonable pricing that include a variety of additional advantages, making it a better deal than paying for individual perks at the hospital. In Vitro means Outside the Body. It is a process of egg fertilization with the sperm outside the body in an embryology laboratory. The process allowed many successful pregnancies in women who were previously deemed infertile. The procedure of IVF involves removal of eggs directly from the ovary, then the eggs are fertilized with sperm in the laboratory, followed by transfer of the embryos directly into the uterus, thereby bypassing the tubes., Grab this comprehensive & discounted package on IVF at Fortis Hospital, Shalimar Bagh, India.


In Vitro Fertilization

Ghaziabad, India

USD 4500 USD 5000

Verfifed

Additional Benefits
Complimentary Stay for 2 in a Hotel for 15 Nights
Free Room Upgrade from Economy to Private
Complimentary Video Consultation with the Specialist
Airport Transfers
City Tour for 2
Priority Appointment
Cancel Anytime with Full Refund
24*7 Patient Care & Support Services

We provide numerous services for your medical journey, including:

  1. Complimentary Stay for 2 in a Hotel for 15 Nights
  2. Free Room Upgrade from Economy to Private
  3. Complimentary Video Consultation with the Specialist
  4. Airport Transfers
  5. City Tour for 2
  6. Priority Appointment
  7. Cancel Anytime with Full Refund
  8. 24*7 Patient Care & Support Services

Costing Details

We provide packages at economical prices with a number of additional benefits which make it a better opportunity than spending actual hospital costs with singular benefits. In Vitro means Outside the Body. It is a process of egg fertilization with the sperm outside the body in an embryology laboratory. The process allowed many successful pregnancies in women who were previously deemed infertile. The procedure of IVF involves the removal of eggs directly from the ovary, then the eggs are fertilized with sperm in the laboratory, followed by the transfer of the embryos directly into the uterus, thereby bypassing the tubes., Grab this comprehensive & discounted package on IVF at Max Super Specialty Hospital, Vaishali, India.


8 Hospitals


The Hospital has a wide architectural structure that consists of-

  • 90+ consultation rooms
  • 108+ private rooms
  • 15 suites and 3 royal suites
  • 10+ operation theatres
  • Neuro-Rehabilitation unit
  • Popular Specialties- Epilepsy, Neuropsychology, Neuro-Ophthalmology, Neuro-Oncology, Clinical Neurology, Memory Disorders, Movement Disorders, Neuro-rehabilitation


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The cost for IVF (In Vitro Fertilization) ranges from USD 7060 - 7620 in Centro Medico Teknon


Apart from in-detail treatment procedures available, Centro Medico Teknon located in Barcelona, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • 60,000 square meters of area
  • 211 wards
  • International visitors program to manage the patient base
  • Cardiovascular Institute and Oncology Institute as specialised centres
  • Assisted Reproduction availaibility
  • Checkup program
  • Plastic & Reparative surgery capacities


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The cost for IVF (In Vitro Fertilization) ranges from USD 7110 - 7560 in Hospital Quirnsalud Barcelona


Apart from in-detail treatment procedures available, Hospital Quirnsalud Barcelona located in Barcelona, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • There are more than 50 healthcare specialties in the hospital.
  • It has different kinds of rooms such as over 130 private rooms, 56 suits, and more than 150 consultation rooms.
  • There are more than 14 operation theatres and 1 robotic surgery theatre is also present.
  • Technologically advanced devices are present in the hospital such as 1 linear accelerator, 2 CAT and 3 MRI scanners.
  • Accommodation, flight booking, transfers and interpreters are available.

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The cost for IVF (In Vitro Fertilization) ranges from USD 6840 - 7660 in Jimenez Diaz Foundation University Hospital


With about 80,000 m 2 , it is equipped with the highest sanitary technology and offers a wide portfolio of services-

  • Day hospital
  • 11 central operating rooms
  • 3 operating rooms for CMA
  • 6 Delivery rooms
  • 686 beds
  • Ambulatory major surgery
  • Emergencies
  • Pediatric emergency
  • ICU
  • Neonatal ICU
  • External Consultations

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The cost for IVF (In Vitro Fertilization) ranges from USD 7090 - 7430 in Quironsalud Marbella Hospital


Apart from in-detail treatment procedures available, Quironsalud Marbella Hospital located in Marbella, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • The hospital is present in an area of 10.500 square meters.
  • A 24- hour emergency service for all kinds of emergency scenarios, even pediatric.
  • There is a specialised radiology department as well as a hemodialysis unit.
  • The hospital also consists of an Intensive Care Unit with a laboratory.
  • Also present are a functional test area with physiotherapy services in addition to functional recovery.
  • Wide network of Insurance partners both national and international.
  • A professionally managed international patient care center.
  • There are more than 25 medical specialties
  • The number of rooms are: 65 plus private rooms, over 14 consultation rooms.
  • There are also more than 5 operation theatres with 2 endoscopy rooms
  • Ultrasound, MRI, CAT scan are also present as per needs and requirements.

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The cost for IVF (In Vitro Fertilization) ranges from USD 7470 - 7640 in University Hospital Quironsalud Madrid


Apart from in-detail treatment procedures available, University Hospital Quironsalud Madrid located in Madrid, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • 54,000 square meters is the area of the hospital.
  • It has huge healthcare capacities with an annual number of 300,000 plus consultations and surgical procedures.
  • The hospital has 39 medical as well as surgical disciplines.
  • There are a variety of rooms available in the hospital which includes 235 individual rooms, as many as 57 suites with 4 royal rooms, 14 Intensive Care unit beds, 8 pediatric ICU beds and 18 Neonatal ICU beds.
  • There are over 70 out-patient clinics present in the hospital.
  • Quironsalud Madrid University Hospital, Madrid has 21 advanced operation rooms.
  • It also possesses one da Vinci surgical robot.
  • The international patient care of the hospital is top notch.

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The cost for IVF (In Vitro Fertilization) ranges from USD 7090 - 7240 in Dexeus University Hospital


Apart from in-detail treatment procedures available, Dexeus University Hospital located in Barcelona, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • There are more than 450 medical professionals working in Dexeus University Hospital, Barcelona, Spain.
  • Facilities include 4 royal suites, 166 single rooms, 13 operating theatres, 564 parking spaces, 5 delivery rooms, day hospital, 140 consultation rooms.
  • The very latest technological and functional equipment and treatment applications.
  • Technological equipment include 1 CAT scanner, 1 PET-CT scanner, 3 MRI scanners, 10 ultrasound machines, 2 neurosurgery surgical microscopes, and 14 operating tables.
  • Care services include Obstetrics area with 24-hour emergency care service, Neonatology Unit and Level III Neonatal ICU, Lung Cancer Early Diagnosis Programme, Rehabilitation and Physiotherapy, Epilepsy Advanced Diagnosis and Emergency Surgery Unit, Congenital Cardiopathy, Growth Disorders and Intensive Care Unit (ICU).
  • Personalised treatment of patients is available.
  • Focus on research based treatment processes and academics.
  • Main international insurance companies are available to provide the best options to the patients.
  • Multilingual personalised care available for patients per their needs and requirements.

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Quironsalud Torrevieja Hospital located in Torrevieja (Alicante), Spain is accredited by ISO. Also listed below are some of the most prominent infrastructural details:

  • The national and international partners of Quironsalud Torrevieja Hospitalmake it a healthcare centre of excellence.
  • The technological upgrades in the hospital have made it the choice of patients in specialties such as Nephrology, Neurology, Orthopedics, Cardiac surgery etc.
  • There are over 35 medical specialties in the hospital.
  • The number of private rooms in the hospital are more than 70 and 45 plus consultation rooms and more than 6 operation theatres.
  • The number of suites are 4 suites and there are 4 royal suites.
  • Ultrasound machines, linear accelerators and even PET-CT, MRI, CAT scan options are present.

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The cost for IVF (In Vitro Fertilization) ranges from USD 5350 - 6140 in Fortis Hospital, Shalimar Bagh


Fortis Hospital, Shalimar Bagh is a super-speciality hospital which occupies a unique place when it comes to providing world class patient care. The hospital is equipped with 262 beds and is expanded over a total area of 7.34 acres. It provides the highest quality of medical care via its team of doctors, technicians, nurses, and management professionals.

Infrastructure & facilities:

  • PET-CT
  • Radiation Oncology: VERSA HD - Elektra (Linac) for Intensity Modulated Radiation Therapy (IMRT), Volumetric Modulated Arc Therapy, Image
  • Guided Radiation Therapy, Stereotactic Radiotherapy, Brachytherapy
  • EUS, 3D Laparoscopic system, Capsule Endoscopy
  • Fibro Scan, Stereotactic Frame for Neurosurgery, ERCP
  • Cardiac Catheterization Lab with Hybrid Operating Room
  • Flat Panel Cath Lab
  • Endo Bronchial Ultrasound
  • 100-Watt Holmium Laser, lithotripsy
  • Flexible Ureteroscope
  • NABH Accredited Hospital
  • NABL Accredited Lab
  • High-tech labs
  • Advanced intensive care units
  • Modular operation theaters
  • Luxury rooms for patients
  • Consultation available on Call / Email / Skype
  • Visa and Travel assistance
  • Local transport available as per the requirements of patients
  • Provision of ambulance/car pickup at airports
  • Rehabilitation facilities wherein experts train you for the therapies and exercises
  • Patient dropped to airports in car / ambulance
  • Fully Air-conditioned Deluxe-Suite rooms
  • Hassle-free discharge as per your flight timings
  • One of Asia’s largest Bone Marrow Transplant Centre
  • Advanced Robotic Surgery Systems
  • Liver Transplant | Kidney Transplant | Heart Transplant
  • Cancer Centre | Centre for Chest and Respiratory Diseases
  • Centre for Child Health | Centre for Critical Care
  • Centre for Bone Marrow Transplant

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The cost for IVF (In Vitro Fertilization) ranges from USD 4580 - 4660 in Jaypee Hospital


Jaypee Hospital located in Noida, India is accredited by ISO, NABH, NABL. Also listed below are some of the most prominent infrastructural details:

  • 525 beds in the first phase
  • 150 Critical Care beds
  • 325 ward beds with Suite, Deluxe, Twin Sharing, and Economy options
  • 18 Modular OTs
  • 4 Cardiac Catheterization Lab with unqie Hybrid Operating Room
  • 24 bedded Advanced Neonatal ICUs20 bedded Dialysis Units
  • 2 Linear Accelerator (IMRT, VMAT, I
  • GRT), Wide Bore CT Simulator, one Brachytherapy Suite
  • True Beam STx Linear Accelerator
  • 2 MRI (3.0 Tesla) with High-Intensity Focused Ultrasound
  • 64 Slice PET CT, Gamma Camera, Dual Head 6 Slice SPECT CT
  • 256 Slice CT Scan, CT Simulation
  • Amongst the few GOLD LEED-certified hospital buildings in India
  • Appointment Scheduling
  • Flow motion 64 Slice PET CT technology
  • Pick and drop facility from/to the Airport
  • Foreign exchange facility
  • Treatment packages
  • Visa assistance
  • Admission in the hospital
  • Wi-Fi/internet service in the room
  • Travel arrangement for patient & attendant after discharge
  • Tele-consults after discharge
  • Dedicated Guest House for International Patients maintained by Jaypee Hospital
  • In-house translators for patient’s comfort
  • Assistance in getting doctor’s opinion
  • Registration with the Foreigners Regional Registration Office
  • Accommodation arrangements after discharge
  • Accommodation arrangement for the accompanying attendant
  • Customized diet for patient and attendant
  • Laundry services
  • Prayer room
  • Dialysis facility for 60 patients
  • Cadaver organs
  • Blood bank facilities
  • Advanced Laboratory facilities
  • Diagnostic and Radiology facilities
  • High-end Ultrasound facilities

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Mount Elizabeth Novena Hospital located in Novena, Singapore is accredited by JCI. Also listed below are some of the most prominent infrastructural details:

  • Capacity of 333 beds
  • Intensive Care Unit beds
  • Endoscopy beds
  • Day ward with 20 beds
  • 13 Operating Theatres, which includes 1 Neurological operating room, 2 Cardiac operating rooms, 4 Orthopaedic operating rooms, etc.
  • High Dependency Unit (HDU)
  • Neonatal Intensive Care Unit (NICU)
  • 24/7 Accident & Emergency Department
  • Maternity ward
  • 1 major operating unit with 13 operating rooms inclusive of 1 hybrid theatre
  • In-house Pharmacy
  • Rooms are categorized as Single Signature Rooms, Junior Suite and Regal Suite
  • All patient rooms are equipped with electric safe, LCD, sofa cum bed, wardrobe, radio channels, and much more

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Types of IVF (In Vitro Fertilization) in Aster Medcity and its associated cost

Treatment OptionApproximate Cost Range (USD)Approximate Cost Range (INR)
Overall IVF Cost2038 - 5057167014 - 417252
Conventional IVF2025 - 4079166014 - 334442
Intracytoplasmic Sperm Injection (ICSI) IVF3039 - 5071250841 - 414907
  • Address: Aster Medcity Hospital, South Chittoor, Kochi, Kerala, India
  • Facilities related to Aster Medcity: Choice of Meals, Interpreter, SIM, TV inside room, Accommodation

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Types of IVF (In Vitro Fertilization) in Medicana Camlica Hospital and its associated cost

Treatment OptionApproximate Cost Range (USD)Approximate Cost Range (INR)
Overall IVF Cost3301 - 5527279437 - 463587
Conventional IVF2297 - 4511188210 - 361682
Intracytoplasmic Sperm Injection (ICSI) IVF3356 - 5718275464 - 462724
  • Address: Kısıklı Mahallesi, MEDICANA ?amlıca Hospital, ?sküdar/Istanbul, Turkey
  • Facilities related to Medicana Camlica Hospital: Post operative followup, Mobility Accessible Rooms, Online Doctor Consultation, Air Ambulance, Religious Facilities

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Types of IVF (In Vitro Fertilization) in Memorial Sisli Hospital and its associated cost

Treatment OptionApproximate Cost Range (USD)Approximate Cost Range (INR)
Overall IVF Cost3407 - 5532270987 - 462353
Conventional IVF2216 - 4468187577 - 362613
Intracytoplasmic Sperm Injection (ICSI) IVF3404 - 5548279677 - 458864
  • Address: Kaptan Paa Mh, Memorial ili Hospital, Halit Ziya T
  • Facilities related to Memorial Sisli Hospital: Choice of Meals, Interpreter, SIM, TV inside room, Accommodation

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Types of IVF (In Vitro Fertilization) in Memorial Ankara Hospital and its associated cost

Treatment OptionApproximate Cost Range (USD)Approximate Cost Range (INR)
Overall IVF Cost3343 - 5589279668 - 455560
Conventional IVF2217 - 4572185111 - 376106
Intracytoplasmic Sperm Injection (ICSI) IVF3312 - 5683272471 - 463160
  • Address: Balgat Mah., Memorial Hospital Ankara, Mevlana Blv. & 1422. Sok., ?ankaya/Ankara, Turkey
  • Facilities related to Memorial Ankara Hospital: Choice of Meals, Interpreter, SIM, TV inside room, Accommodation

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About the IVF (In Vitro Fertilization)

The natural process of fertilization involves the conjugation of an egg and sperm inside the woman’s body. In-vitro-fertilization (IVF) is the procedure that involves the conception of an egg outside the body in a laboratory.  IVF comes under assisted reproductive technology (ART) that involves the use of advanced medical technology to help with pregnancy in the woman.

Which conditions may need IVF support?

  • Blocked Fallopian tubes
  • Endometriosis
  • Advanced age of a woman
  • Decreased sperm count
  • Failure of the treatment with fertility drugs

Types of IVF treatment

The different types of treatments available for IVF are:

  • Natural cycle IVF procedure: In this treatment, the fertility drugs are not administered. The egg released during the normal monthly cycle is collected and then fertilized.
  • Mild stimulation IVF procedure: The lower dose fertility drugs are administered and then the eggs are collected and fertilized.
  • In vitro maturation (IVM): The immature ovaries are collected and then allowed to mature in the laboratory.
  • Embryo transfer: The fertilized embryos are taken and transferred to the mother’s womb.
  • Blastocyst transfer: The embryos are cultured in the laboratory until blastocyst stage and then transferred to the mother’s womb.

IVF with Laser Assisted Hatching

Assisted hatching is a technique used in IVF where a gap or a hole is created on the outer shell of the embryo called zona pellucida before transferring the embryo into the mother’s womb. Before the implantation of the embryo, the developing embryo should “hatch” out of its outer shell (zona pellucida).

Sometimes the embryo is thick, which decreases its ability to hatch on its own. Making a hole or thinning the outer layer may help the embryos to hatch, which increases the chances of pregnancy. Pregnancy cannot occur unless the embryo hatches. Thus, assisted hatching IVF success rates are higher than simple IVF success rates.

Because of the use of additional technology, IVF with laser assisted hatching cost is higher than just IVF cost.

IVF with laser assisted hatching is recommended when:

  • The embryos do not have sufficient energy and nutrients to complete the hatching process
  • The woman is older than 37 years as they are more likely to have thick zona pellucida due to increased levels of follicle stimulating hormones
  • The candidate has had repeated IVF failure
  • The quality of the embryo is poor and demonstrated slow cell division and excessive fragmentation

It is performed by using infrared 1.48-μm diode laser. The technique does not cause any blastocyte damage. Laser assisted hatching has several advantages such as minimal handling of the embryo,  fast delivery, and exact control over the drilling of the hole.

It is performed before transferring the embryo into the mother’s womb on day 3, 5, or 6 after fertilization. An opening in the zona pellucida is created by drilling it with acidified tyrode’s solution.

The embryo is held firmly using holding pipette and a microneedle is applied on the area of zona pellucida. The microneedle is preloaded with Tyrode’s acid using mouth-controlled suction before each micromanipulation.

The acid is expelled over a small area of zona pellucida until it is breached. Suction is applied immediately after the breach of zona pellucida to prevent excess acid entering the embryo. The patients should be provided with antibiotics after implanting the embryo to reduce the risk of infections. 

IVF with Egg Donation

This procedure Is exactly the same as the usual IVF procedure with a difference that the egg used for fertilization comes from a different candidate than the one undergoing IVF. This procedure involves a process known as female egg donation in which a suitable candidate donates an egg for successful fertilization with the retrieved sperms.

The egg donation procedure is similar to how the eggs are retrieved from the womb of the future mother. The only difference is that during egg donation process, the ovaries of the donor are stimulated prior to the collection of suitable number of eggs from the ovaries. All the remaining stems in the donor egg IVF process are similar to the rest of the IVF procedure.

IVF with egg donation is mostly performed in the case of women who have insufficient number of eggs or whose eggs are compromised with respect to quality. The IVF specialist advices the woman to opt for donor eggs in case they believe that there are minimal chances of IVF success because of poor quality of her own eggs.

IVF with ICSI

Intracytoplasmatic sperm injection (ICSI) is an IVF variation in which the sperm is directly injected into the egg for fertilization. The resulting fertilized egg is placed in uterus of the woman. It is the most successful infertility treatment used to treat sperm-related conception problems in couples.

ICSI procedure does not require the sperm to penetrate the layers of the egg. It is highly useful to treat infertility problems in couples who suffer because the male partner’s sperms are either not able to get into the egg or are unable to fertilize the egg even when they are able to get through it.

During IVF with ICSI procedure, the eggs are extracted and held in one place with the help of a glass tool. A single sperm is injected into each egg using a small glass tube. The eggs are cultured and checked for fertilization overnight. The fully fertilized eggs are selected. A few fertilized eggs selected are placed in the uterus with the help of a catheter. The leftover embryos are preserved for future use.

While in simple IVF, the eggs and sperms are mixed together and allowed to fertilize naturally, in ICSI, a sperm is forced into the sperm for fertilization.

ICSI success rates largely depends on the quality of sperms used for fertilization. Overall, the success rate of ICSI is greater than any other technique used as a variation in the IVF procedure.

IVF with ICSI and Donor Sperms

IVF with ICSI is also performed when the sperms come from a suitable donor and not from the male partner of the female undergoing IVF procedure. ICSI IVF treatment is the same when conducted with donor sperms as it is with sperms that come from the male partner.

ICSI treatment involves the injection of a single sperm directly into the egg from the female partner or a donor. In the case of ICSI with donor sperms, a semen sample from a suitable donor is retrieved. The sperm sample is processed and viable and good quality sperms are extracted from for further procedure.

Next, the entire ICSI procedure is conducted in a similar manner. ICSI success rates are the same whether the sperm comes from a donor or the actual male partner. ICSI treatment cost is separate from the cost of IVF.

 

IVF with ICSI and Optical Spindle View

Optical spindle view is a specialized technique used at the time of IVF and ICSI. This technique helps the fertility specialists view the division of cells carefully to ensure that the entire process goes on smoothly.

The optical spindle view technique is used after the fusion of the eggs and the sperms is complete using ICSI as a part of the IVF procedure. The use of this technique helps ensure that the ICSI procedure is successful and that no DNA damage taken place around the site of injection of the sperm.

 

IVF with ICSI and Testicular Biopsy

Sometimes during IVF and ICSI, the fertility specialist may order a testicular biopsy to assess testicular function in the male partner before using his sperms. During testicular biopsy procedure, a small sample of tissue from just one or both the testicles is removed and examined under a microscope. The specialist confirms whether the male partner is fertile or not and accordingly donor sperms are arranged for IVF and ICSI.

 

How is IVF (In Vitro Fertilization) performed?

The steps through which IVF procedure occurs are:

Step 1: Over-stimulation of ovulation

Stimulation of the ovaries occurs with the administration of fertility drugs. The natural process involves the production of one egg per month, but the fertility drugs hyperstimulate the ovaries to produce more number of drugs.

Step 2: Retrieval of eggs

Removal of the eggs from the woman’s body is done through a minor surgery called follicular aspiration surgery. Pain medications are given to the woman and with the help of ultrasound, a thin needle attached to the suction pump is inserted into the vagina. The needle is directed towards the follicles containing eggs and suctions the fluid and the eggs.

Step 3: Insemination

The inactive cells from the semen are removed. The ovum and the sperms are incubated in the ratio of 1:75,000.

Step 4: Fertilization

The sperm enters the egg and fertilization takes place. If the sperm is found to be weak, then Intra-cytoplasmic sperm injection (ICSI) is performed which involves direct injection of sperm into the ovum.

Step 6: Culture of the embryo

After fertilization, the egg divides forming an embryo. The embryo rapidly divides within five days after fertilization.

Genetic diagnosis is performed after 3-4 days of fertilization to rule out the genetic disorders.

Step7: Transfer of the embryo

The embryos are transferred into the mother’s womb after 3-5 days of fertilization. This transfer is done with the help of a thin tube containing embryos. The tube is inserted through the vagina, cervix, and to the womb. Pregnancy is resulted if the embryo starts growing.

Recovery from IVF (In Vitro Fertilization)

Care to be taken after the procedure

  • You can perform your daily living activities from the next day.
  • Continue to take Progesterone pills for 8 to 12 weeks as decrease in progesterone levels may cause miscarriage.

If you have experience symptoms such as fever, pelvic pain, bleeding, and blood in urine, consult your physician immediately.

Patient Stories

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Frequently Asked Questions

What are the treatments related to Infertility offered in Spain

Following are the treatments related to Infertility offered in Spain:

  • IVF/ICSI/IMSI: Severe male infertility and failures with conventional IVF, leads to this approach

Intracytoplasmic morphologically selected sperm injection (IMSI) represent the modern form of ICSI

  • Egg donation (own donor egg bank): A woman donates eggs to enable another woman to conceive

  • Donor sperm: Sperm from the donor obtained by the sperm bank

  • Embryoscope: Uninterrupted viewing of embryos in real-time

  • PGD/PGS: Genetic screening technologies to reduce the risk of passing genetic diseases

  • MACS: Technique that enables sperm with the most superior characteristics to be selected

  • ROPA: Reception of Oocytes from the Partner, where one woman contributes with oocytes and the other with Uterus

  • TESA: Testicular Sperm Aspiration involves collecting sperm through a small needle injected directly in to the testicles

  • Assisted Hatching: Assisted reproductive technology, used in conjunction with conventional IVF treatment to improve the results of IVF

  • Embryo/sperm/egg freezing: Preserving the sperm [require special temperature conditions (-196 degree celcius)]

  • Embryoglue: Medium developed for the embryo transfer

  • Embryo monitoring: Allow embryologists to record the development of the embryos inside at timed intervals

  • ErMap (endometrial receptivity study): Personalised test to diagnose the receptivity status of the endometrium during the window of Implantation

  • ImMap (endometrial immunological study): Immunology tests identify the cause of the failed implantation or miscarriage

  • Advanced sperm test: Semen analysis to quantify active sperm cells and examine the motility

  • Preconception genetic test: Involves blood tests to check whether a woman is likely to conceive a child with a genetic disorder

  • NIPT (Non-Invasive Prenatal Test): a process of characterizing the threat that a fetus will be born with a definite hereditary deformity

  • KIR-HLA genotyping: Genetic test that allows assessing the risks of the embryo being rejected by the maternal immune system

What is the cost IVF and Infertility related treatments in Spain

In Spain, quite a significant variation can be observed in the treatment costs for IVF. For instance, the cost of egg donation starts around €6,500 but some clinics offer this procedure even at €15,000. Initial headline prices may not reveal the ultimate cost and hence the individual has to be scrupulously careful when looking at prices offered by some clinics.

The cost of initial consultation is around €200, and this is not part of the total treatment cost. If the patient is willing to store the sperm, the cost starts from €150 per year of storage. The Embryo vitrification cost is around €400. In this comprehensive package, up to 4 embryos can be vitrified. An additional €100/embryo represents the cost incurred by the individual to vitrify more than 4 embryos. €1800 is the cost of frozen embryo transfer.

€5000-€6000 is the cost for a single treatment of IVF using its own eggs. The several diagnostic tests recommended by the healthcare professional necessary for the treatment are not part of the comprehensive package. The patient has to settle this cost separately. The cost of these tests on the average ranges around €900-€1200. Quite often the medication cost is additionally unincluded in the overall treatment cost.

What are the factors affecting the cost of IVF and other infertility treatments in Spain

IVF is not a single treatment as it seems, but a series of procedures that involve many doctors, nurses, and technicians at each stage of the process. Most of the providers charge a single base fee per IVF cycle which is inclusive of the major costs as charging every particular step separately is quite tedious and confusing. Broadly these costs include Lab tests, ultrasounds, egg retrieval, sperm prep, embryo culture, and embryo transfer.

There are some common costs associated with IVF but are not included in the base per cycle fees are medication, anesthesia, and embryo storage. As each case is unique and the exact procedures necessary for an individual can vary. Apart from the basic IVF protocol, there are a number of supplementary services, procedures, and technologies employed to achieve pregnancy. Few factors that can change the net cost of the IVF cycle are egg/sperm donation, embryo donation, surrogate, assisted hatching, Intracytoplasmic sperm injection (ICSI), Preimplantation genetic screening and diagnosis (PGS and PGD), Testicular sperm extraction (TESE), a success rate of every individual clinic and the non-medical expenses.

What is the success rate of IVF and infertility related treatments in Spain

According to 2018 data published by SEF, the IVF clinical pregnancy rate for IVF for patients with own eggs: under 38 years of age was 55% those with fresh embryos and those with frozen embryos the success rate was 48%

For patients above 38 years of age – 13% (fresh embryos) and 53% (frozen embryos). The success rate data is submitted to the SEF (Spanish Fertility Society).

The egg donation pregnancy success rate for the fresh embryo per embryo transfer is 67% and 54% for frozen embryo transfer. The egg donation clinical pregnancy rate for fresh embryo per embryo transfer is 62% and 46% for the frozen embryo transfer.

What is maximum age for women who can undergo IVF Treatment

Age remains the most crucial factor influencing the outcome of an IVF cycle. The maximum legal age limit to carry out the IVF procedure is 50. However, age restrictions for IVF treatment vary from clinic to clinic, considering the expertise and treatment options available with them. Generally, women above 40 years of age have markedly lower chances of live birth compared to women less than age 40. Most of the clinics hesitate from treating the patients above 42.

Measurement of a woman’s FSH and Oestradiol levels on cycle day 3 can predict the chances for successful IVF treatment. Elevation in either hormone can lead to failure and hence more elderly women with elevated hormone levels on day 3 are suggested for donor eggs or adoption.

How does the IVF Procedure take place in Spain

Initially, the IVF doctor or the fertility specialist will evaluate the hormone levels and menstrual cycle. An individual may be sought to undergo a transvaginal ultrasound to ensure the healthiness of the ovaries and the general reproductive system. The doctor may recommend medication or a plan of action if needed.

Once the body reaction to specific medications mapping is done, the doctor may switch on to fertility medications. Fertility medications help the follicles in the ovaries to produce eggs.

Post this, the doctor may proceed with the retrieval of eggs from the follicles of the ovaries. If the individual has decided to advance with the donor eggs the process is carried out with the donor or the frozen eggs are collected. The donor’s/partner’s sperm is also collected.

Post egg retrieval the fertility lab is all set for insemination of egg and sperm. Fertilized eggs become the embryo, and those embryos which are unplanned to be transferred will be frozen. Embryos developed from fertilization, are placed in the uterus normally after 3 to 5 days after retrieval.

If the process is successful, pregnancy will occur and the IVF process will be considered as a success. If this cycle fails, the doctor may use another frozen embryo.

The amount of time consumed at the individual stage is completely dependent on how the body responds to the treatment. Age plays a crucial role in IVF treatments. Supplementary and advanced procedures may be employed at various stages as suggested by the specialists.

What are best cities in Spain for IVF Treatment

The most prominent cities for IVF treatments in Spain are Madrid, Barcelona, Alicante, and Valencia.

Which are the best rated clinics in Spain for In Vitro Fertilization (IVF)

Top clinics in Spain

  • Juaneda Fertility Center:

A part of the large healthcare provider network, Juaneda fertility center adopts the most advanced techniques. Healthcare professionals are highly experienced and provide comprehensive service to patients.

  • Manzanera Medical Center:

40+ years of experience in assisted reproductive treatments and Gynaecology, the clinic is ISO 9001 certified.

  • CERAM Clinic:

The clinic reports a higher success rate for pregnancy than the national average. 25+ years of experience in assisted reproductive treatments and gynecology, the clinic has the modern-day infrastructure and exploits the most recent trends and technologies

  • Barcelona IVF:

One of the most premier clinics in Spain, the facility has the most advanced instruments. Modern infrastructure is comprehensively suitable to host international medical tourists.

  • HC Marabella International Hospital:

Equipped with pioneering laboratory techniques, the clinic is at the forefront of disposing of most advanced care. The clinic employs individual treatment plans that provide comprehensive care to the patients.

  • IREMA, Alicante

Preserving the excellence in the IVF treatments, the clinic has its own laboratories.

  • MAR&Gen Clinic:

30+ years’ experience in the assisted reproductive treatment domain, the clinic exploits cutting-edge technology and equipment.

Which are the top IVF Specialists in Spain

The top IVF Specialists:

  • Dr. Hugo Benito:

Founder medical director of CERAM hospital, Dr. Hugo Benito has 35+ years of experience in obstetrics and Gynaecology.

  • Dr. Raúl Olivares:

23+ years’ experience of working in assisted reproductive treatments, Dr. Raul Olivares is currently associated with Barcelona IVF.

  • Dr. Juan Manuel Marín:

Specialist in andrology and assisted reproductive treatments, Dr. Juan Manuel Marin is currently associated with HC Marabella International Hospital.

  • Dr. Natalia Szlarb

The medical director of the IVF Spain clinic, Dr. Natalia Szlarb has worked across several parts of the globe. False