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Lesionectomy is a specialised brain surgery designed to remove abnormal tissue causing seizures or other neurological issues, especially in patients who do not respond well to medications. It targets specific brain lesions identified through detailed imaging and diagnostic evaluations.

The procedure involves opening a small part of the skull (craniotomy) to access and carefully remove the lesion, with the help of advanced tools like brain mapping and surgical navigation to avoid damage to healthy brain areas.

Lesionectomy can significantly reduce or stop seizures and may also improve cognitive and functional abilities. Recovery depends on the lesion’s location and complexity, and patients are often supported with short-term rehabilitation and ongoing medical follow-up.

A lesionectomy is a type of brain surgery performed to remove abnormal brain tissue (lesions) that are causing seizures or other neurological problems. These lesions may include tumours, vascular malformations, cortical dysplasia, scarring, or other abnormal brain structures. Lesionectomy is often used to treat drug-resistant epilepsy when seizures originate from a well-defined lesion identifiable on brain imaging. By removing the lesion, the surgery aims to reduce or eliminate seizures and preserve surrounding healthy brain tissue.

You should see a neurologist or neurosurgeon if you experience:
  • Frequent or uncontrolled seizures, especially if medications are ineffective
  • Neurological symptoms such as weakness, vision changes, speech difficulties, or memory problems
  • Changes in personality or cognition
  • Brain imaging (MRI, CT) that shows a lesion with unclear or suspicious features
Persistent neurological issues or structural brain abnormalities may indicate the need for further evaluation, possibly leading to surgical treatment like lesionectomy.

Preparation involves a comprehensive evaluation by a multidisciplinary epilepsy or neurology team:
  • Neuroimaging: MRI, PET, or CT scans to locate the lesion
  • EEG monitoring: To map seizure activity and confirm the lesion as the source
  • Neuropsychological testing: To assess memory, language, and cognitive functions
  • Functional MRI or brain mapping: To identify areas responsible for vital functions like speech or movement
  • Medication review: Some drugs may be paused or adjusted before surgery
  • Fasting: Usually required 6–8 hours before the procedure
Patients will meet with an anesthesiologist and surgeon to review risks, benefits, and expected outcomes.

  • Anaesthesia: The patient is placed under general anaesthesia.
  • Craniotomy: A portion of the skull is carefully opened to access the brain.
  • Navigation and Mapping: Advanced imaging and intraoperative brain mapping guide the surgeon to locate the lesion precisely.
  • Lesion Removal: The abnormal tissue is removed, taking care to avoid surrounding healthy or functional areas.
  • Closure: The bone flap is replaced, and the scalp is sutured.
Depending on the lesion's location and the patient's condition, surgery may last 2 to 6 hours.

A lesionectomy usually takes 2 to 6 hours, depending on lesion size, location, and complexity. Patients typically stay in the hospital for 3 to 7 days for observation and early recovery.

Although lesionectomy is generally safe, potential risks include:
  • Infection
  • Bleeding
  • Brain swelling
  • Neurological deficits (speech, memory, or motor issues, depending on location)
  • Seizures after surgery
  • Cerebrospinal fluid leakage
  • Anesthesia-related complications
These risks vary depending on the type, size, and location of the lesion in the brain.

  • Seizure reduction or elimination, especially in drug-resistant epilepsy
  • Improved quality of life, cognitive function, and independence
  • Minimal disruption to the surrounding brain tissue when precisely targeted
  • Increased effectiveness of medications post-surgery, if still required
  • It can sometimes eliminate the need for lifelong anti-seizure medication
Lesionectomy is a valuable option when the abnormal area can be safely removed.

After surgery:
  • Patients are initially monitored in the ICU and then transferred to a regular neurology unit.
  • Headaches, fatigue, or confusion are common during early recovery.
  • Physical, occupational, or speech therapy may be needed depending on outcomes.
  • Most patients resume light activities in 2 to 4 weeks and return to work or school within 6 to 8 weeks.
  • Follow-up includes neuroimaging, EEGs, and ongoing neurology consultations.
Patients must attend all post-operative visits and continue taking prescribed medications as advised.

Lesionectomy has a high success rate, especially in patients with focal epilepsy and identifiable lesions. Studies show that 60–80% of patients become seizure-free after surgery, and many experience improved cognitive and psychological function.

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Explore Hospitals ( 219 )
Lesionectomy in Meliva Kardiolita Hospital, Kaunas: Costs, Top Doctors, and Reviews

Kaunas, Lithuania

  • Joint Commission International, or JCI

Apart from in-detail treatment procedures available, Kardiolita Hospital, Kaunas located in Kaunas, Lithuania has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals. Also listed below are some of the most prominent infrastructural details:

  • An outpatient department, 56-beds for inpatients
  • 13 advanced operation theatres
  • 24-hour intensive care unit
  • Emergency Department
  • Gynecology Center
  • Vascular Center
  • ENT Center
  • Neurology Center
  • General and Abdominal Surgery Center
  • The staff also takes care of your air travel and pick & drop facility
  • Gynecology Center
  • Vascular Center
  • ENT Center
  • Neurology Center
  • General and Abdominal Surgery Center
  • The staff also takes care of your air travel and pick & drop facility
Lesionectomy in Sagrat Cor University Hospital: Costs, Top Doctors, and Reviews

Barcelona, Spain

The Hospital is an amalgamation of a group of buildings located in the Eixample Left of Barcelona, ??between Paris, Viladomat, and London streets. It has a capacity of 350 adjustable beds and first-class hotel-like services inpatient rooms. Currently, it has a workforce of about 1100 Healthcare Professionals. 

In order to treat patients with intensive care, the Hospital has 10 beds in its ICU for critically ill patients. 

The Hospital has launched a few more things to improve customers’ services- 4 new Operating Rooms and a New Diagnostic Imaging Service.

Other Services

  • Surgical Block with 13 major surgery operating rooms, 5 operating rooms for Minor Surgeries, 1 for Dermatology Service
  • The Non-Admitted Surgery Unit (UCSI) Major Outpatient Surgery (CMA) has a total of 14 units to care for major surgery patients who do not require admission to hospitalization
  • Rehabilitation Center with treatment boxes and group therapy room, Gym, Medical visit offices, priests rooms, waiting rooms, and others 
  • 7 Examination Cabinets 
  • The pediatric patients waiting room 
  • Emergency Center-12 emergency boxes, 1 double resuscitation box, and 7 rapid visit offices

Types of Room

Double Rooms, Double Rooms for Individual Use, and Single Rooms; equipped with an easy-to-use electrical movement control system and a nursing call/warning system, located at the head of the bed, a sofa-bed for the companion, and a bathroom with a shower. They are also equipped with television and telephone.

A cafeteria/Restaurant is also available for the patients or visitors.

Lesionectomy in Bishops Wood Hospital: Costs, Top Doctors, and Reviews

Northwood, United Kingdom

Bishops Wood Hospital is a 42 bedded acute care unit located in Middlesex, UK. Offering treatment and diagnostic services for more than 25 specialties, the hospital was established to offer the highest standard of care and services to patients from across the world. The hospital is a part of the private Circle Healthcare Group, which is a leading provider of state-of-the-art healthcare services and has multiple hospitals and clinics across the world. 

The hospital has over 120 specialists and surgeons working with them to provide a variety of surgical and non-surgical treatments to people. The hospital is particularly known for a variety of orthopedic procedures that are carried out, including knee and hip surgery, hand and wrist surgery, foot and ankle surgery, and shoulder and elbow surgery. The hospital has been instrumental in slowly expanding its medical service and now offers treatments to patients requiring primary, secondary as well as tertiary care. 

The hospital boasts of its team of medical and nursing staff, which is available 24 hours a day. Every medical specialist is a part of a multidisciplinary team, which includes specialists from the in-house radiology and physiotherapy department.

  • More than 20 specialties
  • Especially known for orthopedic surgeries and radiology
  • Patient-friendly and comfortable environment
  • Offers full privacy to patients

Facilities Provided:

  • Personalized Meals and Diet Support
  • Full en-suite facilities with bath or shower
  • Immediate access to nursing support
  • Car parking
  • Satellite television, radio, and direct dial telephone inside the room
Lesionectomy in The Alexandra Hospital: Costs, Top Doctors, and Reviews

Cheadle, United Kingdom

  • National Accreditation Board for Hospitals & Healthcare Providers (NABH)

The Alexandra Hospital has access to modern equipment and private facilities for patients in Manchester, Stockport, and Cheshire. The hospital offers Outpatient Services to children from 0-18 years and day-case inpatient procedures for 3-18 years.

Established in 1981, the hospital is a 128-bedded facility offering treatments in more than 20+ specialties. The hospital has a friendly and caring staff. Equipped with world-class technology, the hospital is known for safe and effective outcomes across a wide range of treatments-from complex cases to minor surgery.

The Alexandra Hospital has dedicated radio imaging and biochemistry departments offering a wide range of tests being performed like X-ray, Ultrasound, CT Scan, MRI, DEXA Scan, etc.

The hospital ensures patient safety and provides an ideal environment with trained and experienced staff and a resident team available for 24 hours.

The hospital has efficient patient care that works hard to make each patient's time as pleasant as possible.

Lesionectomy in Max Super Specialty Hospital, Shalimar Bagh: Costs, Top Doctors, and Reviews

Delhi, India

  • National Accreditation Board for Hospitals & Healthcare Providers (NABH)
  • National Accreditation Board for Testing and Calibration Laboratories (NABL)
  • Max Super Speciality Hospital, Shalimar Bagh, is a 402-bed quaternary-care hospital in New Delhi, offering advanced treatment across 37+ specialities, including Cancer, Cardiac, Neurosciences, Gastroenterology, Orthopaedics, and Renal Transplant.
  • Equipped with state-of-the-art technology and a team of highly skilled doctors and nurses, the hospital provides complex procedures, minimally invasive surgeries, and targeted cancer treatments, making it one of India’s leading healthcare destinations.
Lesionectomy in Amrita Hospital: Costs, Top Doctors, and Reviews

Faridabad, India

  • National Accreditation Board for Hospitals & Healthcare Providers (NABH)

Founded in 1998 by Mata Amritanandamayi (Amma), the Amrita Institute of Medical Sciences and Research Centre is one of India’s leading healthcare institutions, accredited by ISO, NABH, and NABL. With 2 branches, 7 medical colleges, and a network of 800+ doctors and 2,600+ beds, it offers comprehensive care across 81 specialties and 12 super-specialty departments, supported by 60+ modern operating theatres and 534 critical care beds. The Faridabad campus, a world-class multispeciality facility, houses advanced centers for oncology, neurosciences, cardiac sciences, gastro-sciences, mother and child care, and trauma care, along with India’s most comprehensive infectious disease unit. Guided by a mission of compassion and innovation, Amrita Hospitals combine cutting-edge medicine with humanitarian service to empower communities and promote holistic well-being.

Lesionectomy in Rajagiri Hospital: Costs, Top Doctors, and Reviews

Kochi, India

  • Joint Commission International, or JCI
  • Rajagiri Hospital, Kochi, Kerala, is a leading multi-speciality tertiary care hospital known for providing world-class medical services with advanced technology and compassionate care.
  • Accredited by JCI, NABH, and NABL, the hospital offers comprehensive treatment across specialities like Cardiology, Oncology, Neurology, Gastroenterology, Orthopaedics, Nephrology, Urology, and Paediatrics, making it a trusted healthcare destination in South India.
Lesionectomy in Bukit Tinggi Medical Centre: Costs, Top Doctors, and Reviews

Kuala Lumpur, Malaysia

As a tertiary care hospital, Bukit Tinggi Medical Centre (BTMC) is committed to providing high-quality, reasonably priced healthcare.

With a focus on patient care and a team of committed medical professionals and personnel, we want to realize our ambition of becoming Klang's go-to healthcare provider. Orthopedics, neurosurgery, cardiac surgery, obstetrics and gynecology, pediatrics and rehabilitation, aesthetic surgery, and other specialties are all part of our multidisciplinary team approach. Additionally, BTMC has a Health Screening Center that provides a range of health packages to meet the requirements of diverse patient types.

Lesionectomy in Catalunya General University Hospital: Costs, Top Doctors, and Reviews

Barcelona, Spain

  • ISO 9001
  • A 328-bed capacity, offering comfortable rooms with modern facilities for patient recovery.
  • Twenty-two intensive care beds are available for adults, children, and newborns needing close monitoring.
  • Seventeen advanced surgical theatres are used for different operations, from general to highly specialised surgeries.
  • Over 120 medical consultation rooms where patients receive personalised outpatient care.
  • A full suite of diagnostic imaging tools, including MRI, CT, and ultrasound, for accurate medical evaluations.
  • A round-the-clock emergency department equipped to handle urgent and critical health issues.
  • Dedicated units for neurology and neurosurgery, treating conditions such as stroke, epilepsy, and nerve disorders.
  • Neurological testing facilities, including EEG and EMG, are available for detailed assessments of the brain and nerves.
  • A strong focus on rehabilitation, helping patients recover from surgeries, injuries, or neurological events.
  • A maternity area designed for safe deliveries, with neonatal support for newborn care.
  • A day hospital section allows patients to get procedures or therapies without an overnight stay.
  • On-site services, including a pharmacy and laboratory, are available to streamline patient care and testing.
  • Support for international patients, including multilingual staff and travel and care planning assistance.
  • Additional conveniences include a cafeteria, family waiting areas, and ample parking spaces.

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Process Involved for Lesionectomy

  • Preoperative Evaluation: This includes a neurological exam, EEG, MRI, and sometimes intracranial monitoring to localise the lesion.
  • Surgical Planning: Advanced imaging and brain mapping are used to plan a safe and precise lesion removal.
  • Surgery (Lesionectomy): The identified brain lesion is surgically removed through a craniotomy.
  • Intraoperative Monitoring: Brain function is continuously monitored to protect vital areas of the brain.
  • Postoperative Care: Includes observation in the ICU, pain management, and neurological assessments.
  • Rehabilitation: This may involve physical, occupational, or speech therapy, depending on the specific brain area affected.
  • Follow-up and Monitoring: Conduct long-term follow-up, including imaging and seizure monitoring, to assess outcomes and evaluate the effectiveness of treatment.
  • Drug-resistant epilepsy: Lesionectomy is performed when seizures persist despite optimal medication.
  • Low-grade gliomas: The surgery removes slow-growing brain tumours that contribute to seizure activity.
  • Cortical dysplasia: Abnormal brain tissue responsible for seizures is surgically eliminated.
  • Cavernous malformations: These vascular lesions, which cause recurrent seizures, are safely excised.
  • Gangliogliomas: Rare tumours made up of nerve and glial cells are removed to help manage epilepsy.
  • Dysembryoplastic neuroepithelial tumours (DNETs): Benign brain growths that trigger seizures are taken out.
  • Arteriovenous malformations (selected cases): Certain vascular abnormalities linked with seizures are treated surgically.
  • Benign brain lesions causing seizures: Non-cancerous brain abnormalities that generate seizures are targeted and removed.
  • Hamartomas: These non-cancerous tissue overgrowths are excised when they cause epilepsy.
  • Epileptogenic brain tumours: Tumours acting as a source of seizures are surgically treated.
  • Neurological evaluation to confirm seizure origin or lesion-related symptoms.
  • Imaging tests, such as MRI, CT scans, and PET scans, are used to locate the lesion accurately.
  • EEG or intracranial monitoring to identify abnormal electrical activity.
  • Surgical planning using neuronavigation and functional mapping.
  • Craniotomy to access the lesion in the brain.
  • Precise removal of the abnormal tissue causing seizures or symptoms.
  • Intraoperative monitoring is used to ensure the safety of the surrounding brain areas.
  • Closure of the surgical site and transfer to recovery or ICU for observation.
  • Postoperative imaging to confirm complete lesion removal.
  • Ongoing follow-up for seizure control and neurological function evaluation.
  • Craniotomy
  • Electrocorticography (ECoG)
  • Stereoelectroencephalography (SEEG)
  • Neuronavigation
  • Intraoperative MRI
  • Cortical mapping
  • Functional MRI (fMRI)
  • Brain biopsy
  • Intracranial EEG monitoring
  • Awake craniotomy
  • Seizure control in patients with drug-resistant epilepsy
  • Improved quality of life due to reduced or complete seizure freedom
  • Preservation of brain function by targeting only the lesion
  • Minimally invasive options are available in selected cases
  • Faster recovery time compared to extensive brain surgeries
  • Reduced medication dependence, often leading to dose reduction or discontinuation
  • Accurate diagnosis and treatment, when combined with advanced imaging and monitoring techniques
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Fauzia Zeb Fatima
Fauzia Zeb Fatima

M.Pharm

4 Years of Experience

Fauzia Zeb is a distinguished medical and scientific content writer with a robust academic foundation in pharmaceutical sciences, holding a B.Pharm and M.Pharm degree from prestigious institutions, including MIT and Jamia Hamdard University. Her comprehensive expertise in pharmacology, clinical sciences, and biomedical research enables her to translate complex medical and scientific concepts into precise, evidence-based content tailored for diverse audiences. Specializing in peer-reviewed articles, clinical blog posts, and research-driven publications, she demonstrates a consistent ability to bridge the gap between advanced medical science and accessible, audience-specific communication.. View More

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⁠Dr Rakesh Kumar Dua
⁠Dr Rakesh Kumar Dua

Spine & Neurosurgeon

25 Years of Experience

Dr. Rakesh Dua has more than 25+ years of clinical experience in spine surgeries. He is currently providing his services as Director, Neuro & Spine Surgery at Fortis Hospital, Shalimar Bagh. Before joining Fortis Hospital, he was associated with Max super-specialist Hospital, Shalimar Bagh as Director Neurosurgery & Head Neuro Spine, and with UCMS & GTB hospital as head of the neurosurgery department. View More

Last Reviewed - January 2026