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Lesionectomy is a specialised brain surgery designed to remove abnormal tissue causing seizures or other neurological issues, especially in patients who do not respond well to medications. It targets specific brain lesions identified through detailed imaging and diagnostic evaluations.
The procedure involves opening a small part of the skull (craniotomy) to access and carefully remove the lesion, with the help of advanced tools like brain mapping and surgical navigation to avoid damage to healthy brain areas.
Lesionectomy can significantly reduce or stop seizures and may also improve cognitive and functional abilities. Recovery depends on the lesion’s location and complexity, and patients are often supported with short-term rehabilitation and ongoing medical follow-up.
A lesionectomy is a type of brain surgery performed to remove abnormal brain tissue (lesions) that are causing seizures or other neurological problems. These lesions may include tumours, vascular malformations, cortical dysplasia, scarring, or other abnormal brain structures. Lesionectomy is often used to treat drug-resistant epilepsy when seizures originate from a well-defined lesion identifiable on brain imaging. By removing the lesion, the surgery aims to reduce or eliminate seizures and preserve surrounding healthy brain tissue.
You should see a neurologist or neurosurgeon if you experience:
- Frequent or uncontrolled seizures, especially if medications are ineffective
- Neurological symptoms such as weakness, vision changes, speech difficulties, or memory problems
- Changes in personality or cognition
- Brain imaging (MRI, CT) that shows a lesion with unclear or suspicious features
Preparation involves a comprehensive evaluation by a multidisciplinary epilepsy or neurology team:
- Neuroimaging: MRI, PET, or CT scans to locate the lesion
- EEG monitoring: To map seizure activity and confirm the lesion as the source
- Neuropsychological testing: To assess memory, language, and cognitive functions
- Functional MRI or brain mapping: To identify areas responsible for vital functions like speech or movement
- Medication review: Some drugs may be paused or adjusted before surgery
- Fasting: Usually required 6–8 hours before the procedure
- Anaesthesia: The patient is placed under general anaesthesia.
- Craniotomy: A portion of the skull is carefully opened to access the brain.
- Navigation and Mapping: Advanced imaging and intraoperative brain mapping guide the surgeon to locate the lesion precisely.
- Lesion Removal: The abnormal tissue is removed, taking care to avoid surrounding healthy or functional areas.
- Closure: The bone flap is replaced, and the scalp is sutured.
A lesionectomy usually takes 2 to 6 hours, depending on lesion size, location, and complexity. Patients typically stay in the hospital for 3 to 7 days for observation and early recovery.
Although lesionectomy is generally safe, potential risks include:
- Infection
- Bleeding
- Brain swelling
- Neurological deficits (speech, memory, or motor issues, depending on location)
- Seizures after surgery
- Cerebrospinal fluid leakage
- Anesthesia-related complications
- Seizure reduction or elimination, especially in drug-resistant epilepsy
- Improved quality of life, cognitive function, and independence
- Minimal disruption to the surrounding brain tissue when precisely targeted
- Increased effectiveness of medications post-surgery, if still required
- It can sometimes eliminate the need for lifelong anti-seizure medication
After surgery:
- Patients are initially monitored in the ICU and then transferred to a regular neurology unit.
- Headaches, fatigue, or confusion are common during early recovery.
- Physical, occupational, or speech therapy may be needed depending on outcomes.
- Most patients resume light activities in 2 to 4 weeks and return to work or school within 6 to 8 weeks.
- Follow-up includes neuroimaging, EEGs, and ongoing neurology consultations.
Lesionectomy has a high success rate, especially in patients with focal epilepsy and identifiable lesions. Studies show that 60–80% of patients become seizure-free after surgery, and many experience improved cognitive and psychological function.
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Hisar Intercontinental Hospital
Istanbul, Turkey
Architecture of the Hospital designed as per the comfort of patients-
- Consisting of 8 floors, 212 bed capacity
- 75m2 suite rooms
- 35 thousand m2 closed area
- 7 operating rooms
- 53 polyclinics
- 54 Departments
- Hotel-like patient rooms
- Intensive care units consisting of 33 beds
- Hyperbaric Oxygen Center inside the hospital
- PYXIS computerized medicine system working with fingerprint
- Social waiting areas
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NMC Specialty Hospital
Abu Dhabi, United Arab Emirates
NMC Specialty Hospital located in Abu Dhabi, United Arab Emirates is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- 104 Patient Rooms/Wards
- 7 Operating Rooms
- Laboratory endowed with centrally computerized System
- 24-hour Emergency Department
- 24-hour Pharmacy
- 24-hour Ambulance Services
- Radiology Department offering state-of-the-art equipment, including MRI (1.5 Tesla), 64-slice spiral CT Scanner, 4-D Ultrasound with color Doppler, Bone Densitometry, Digital Mammogram with CAD System, and Digital X-Ray Systems with fully integrated PACS
NMC Specialty Hospital, Al Nahda
Dubai, United Arab Emirates
4.7 ( 2 Reviews )
NMC Specialty Hospital, Al Nahda located in Dubai, United Arab Emirates is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- 72 Patient Rooms
- 10 ICU Beds
- 10 NICU Beds
- 4 Operation Theatres
- Well-equipped Laboratory
- Radiology Department
- Smaller Medical Centers and Clinics in Dubai
- Advanced Technology used by the Hospital- a patient friendly closed MRI (1.5 tesla), 64 Slice - Dual Source Siemens Definition MDCT CT scanner, 4-D Ultrasound with Color Doppler, Digital Fluoroscopy, Mammogram, and Digital X - Ray systems backed by a fully integrated PACS system
- 24-hour In-house Pharmacy
- 24-hour Ambulance services
Tel Aviv Sourasky Medical Center -Ichilov Hospital
Tel Aviv, Israel
Tel Aviv Sourasky Medical Center -Ichilov Hospital located in Tel-Aviv, Israel is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- The center possesses high end infratsructure with latest technologies which are upbgraded on a regular basis.
- There are 60 departments in Tel Aviv Sourasky Medical Center
- The center has as many as 6 institutions:
- Ichilov General Hospital
- Ted Arison Medical Tower
- Dana-Dwek Children's Hospital
- Sammy Ofer Heart & Brain Building
- Adams Health Science & Rehabilitation Building (in the planning stage)
- Lis Maternity and Women's Hospital
- Patient Care Numbers (annual) are as follows:
- 400,000 patients
- 36,000 surgeries
- 220,000 ER visits
- 12,000 births
- The bed capacity of the center is 1300.
- Good success rates during treatment for the majority of conditions.
Max Smart Super Speciality Hospital
Delhi, India
3.9 ( 2 Reviews )
- Max Smart Super Speciality Hospital, Saket, New Delhi, is a 250-bed tertiary care hospital known for advanced medical technology and patient-centred care.
- The hospital offers services across 22+ specialities, including Cardiac Sciences, Orthopaedics, Urology, Neurology, Neurosurgery, Paediatrics, Obstetrics, and Gynaecology.
- It is a regional hub for complex procedures such as neurovascular interventions, targeted cancer treatments, heart surgeries, kidney and liver transplants, and bariatric care.
- Equipped with a 3.0 Tesla MRI, 256 Slice CT Angio, Cath Labs, Digital Orthopaedic Suite, and advanced diagnostic tools, and supported by 275+ doctors and 606+ trained staff, Max Smart Saket provides high-quality, multidisciplinary care for domestic and international patients.
Lifecare Hospital, Musaffah
Abu Dhabi, United Arab Emirates
Lifecare Hospital, Musaffah located in Abu Dhabi, United Arab Emirates is accredited by ISO, JCI. Also listed below are some of the most prominent infrastructural details:
- Inpatient Pharmacy
- Outpatient Pharmacy
- Nursing Department
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- Rehabilitation Center
Acibadem Kadikoy Hospital
Istanbul, Turkey
Acibadem Kadikoy Hospital located in Istanbul, Turkey is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- The number of beds in the hospital are 138 and Intensive Care beds are 23.
- There are as many as 6.500 access points for a building control system.
- There are 10 Operating theatres and more than 500 employees.
- There are specific healthcare facilities in Acibadem Kadikoy Hospital, Istanbul, Turkey which have been established per integrated healthcare outreach such as Breast Health Center, Check-up Center, and Diabetes Clinic etc.
- The hospital has the very best of Medical Technologies such as Flast CT, da Vinci robot, Magnetom Area MRI, Greenlight, Ortophos XG 3D and Full Body MRI, 4-Dimensional Breast Ultrasound, 3-Dimensional Tomosynthesis Digital Mammography.
Thumbay University Hospital, Ajman
Ajman, United Arab Emirates
4.1 ( 1 Reviews )
Thumbay University Hospital, Ajman located in Ajman, United Arab Emirates is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- The hospital has a 250 bed capacity.
- Excellent quality of healthcare facilities and services at par with developed countries.
- Multilingual and multinational healthcare professionals working in the Thumbay Hospital Ajman (belonging to 20 nations and fluent in 50 plus languages).
- Equipped with the newest facilities to ensure highest standards of healthcare delivery to patients at economical costs.
- Dedicated, compassionate and highly educated healthcare professionals work in Thumbay Hospital Ajman.
- Well developed diagnostic facilities are also available.
- A 24/7 functioning emergency care department and advanced facilities in Radiology.
- There is presence of an ultramodern Catheterization Lab (Cath Lab) and Electrosurgery Cryotherapy in dermatology, Interlocking intramedullary nailing.
- Also available under dental departments Panoramic, digital intra-oral X-rays, Cephalogram are present.
- Some of the important specialties in Thumbay Hospital Ajman are:
- Ear, nose, and throat
- Cardiovascular
- Bariatric surgery
- General surgery
- Urology
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Lokman Hekim Esnaf Hospital
Fethiye, Turkey
Lokman Hekim Esnaf Hospital located in Fethiye, Turkey is accredited by ISO. Also listed below are some of the most prominent infrastructural details:
- The patients rooms have been designed to simulate hotel comfort; homely private rooms equipped with spacious en suite bathrooms, television and Wi-fi
- Rehabilitation Center
- Emergency Department
- ICU
- International Patient Department comprises of a Medical Doctor, a tourism doctor, a manager, an assistant manager and 7 officers
Medical Park Karadeniz Hospital
Trabzon, Turkey
Apart from in-detail treatment procedures available, Medical Park Karadeniz Hospital located in Trabzon, Turkey has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, TV inside room. Also listed below are some of the most prominent infrastructural details:
- Situated in an area of 12.000 square meter
- Capacity of 107 beds
- Intensive Care Unit (17 beds)
- Neonatal ICU (NICU- 12 beds)
- 6 Operating Rooms
- Cafeteria
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+99Process Involved for Lesionectomy
- Preoperative Evaluation: This includes a neurological exam, EEG, MRI, and sometimes intracranial monitoring to localise the lesion.
- Surgical Planning: Advanced imaging and brain mapping are used to plan a safe and precise lesion removal.
- Surgery (Lesionectomy): The identified brain lesion is surgically removed through a craniotomy.
- Intraoperative Monitoring: Brain function is continuously monitored to protect vital areas of the brain.
- Postoperative Care: Includes observation in the ICU, pain management, and neurological assessments.
- Rehabilitation: This may involve physical, occupational, or speech therapy, depending on the specific brain area affected.
- Follow-up and Monitoring: Conduct long-term follow-up, including imaging and seizure monitoring, to assess outcomes and evaluate the effectiveness of treatment.
- Drug-resistant epilepsy: Lesionectomy is performed when seizures persist despite optimal medication.
- Low-grade gliomas: The surgery removes slow-growing brain tumours that contribute to seizure activity.
- Cortical dysplasia: Abnormal brain tissue responsible for seizures is surgically eliminated.
- Cavernous malformations: These vascular lesions, which cause recurrent seizures, are safely excised.
- Gangliogliomas: Rare tumours made up of nerve and glial cells are removed to help manage epilepsy.
- Dysembryoplastic neuroepithelial tumours (DNETs): Benign brain growths that trigger seizures are taken out.
- Arteriovenous malformations (selected cases): Certain vascular abnormalities linked with seizures are treated surgically.
- Benign brain lesions causing seizures: Non-cancerous brain abnormalities that generate seizures are targeted and removed.
- Hamartomas: These non-cancerous tissue overgrowths are excised when they cause epilepsy.
- Epileptogenic brain tumours: Tumours acting as a source of seizures are surgically treated.
- Neurological evaluation to confirm seizure origin or lesion-related symptoms.
- Imaging tests, such as MRI, CT scans, and PET scans, are used to locate the lesion accurately.
- EEG or intracranial monitoring to identify abnormal electrical activity.
- Surgical planning using neuronavigation and functional mapping.
- Craniotomy to access the lesion in the brain.
- Precise removal of the abnormal tissue causing seizures or symptoms.
- Intraoperative monitoring is used to ensure the safety of the surrounding brain areas.
- Closure of the surgical site and transfer to recovery or ICU for observation.
- Postoperative imaging to confirm complete lesion removal.
- Ongoing follow-up for seizure control and neurological function evaluation.
- Craniotomy
- Electrocorticography (ECoG)
- Stereoelectroencephalography (SEEG)
- Neuronavigation
- Intraoperative MRI
- Cortical mapping
- Functional MRI (fMRI)
- Brain biopsy
- Intracranial EEG monitoring
- Awake craniotomy
- Seizure control in patients with drug-resistant epilepsy
- Improved quality of life due to reduced or complete seizure freedom
- Preservation of brain function by targeting only the lesion
- Minimally invasive options are available in selected cases
- Faster recovery time compared to extensive brain surgeries
- Reduced medication dependence, often leading to dose reduction or discontinuation
- Accurate diagnosis and treatment, when combined with advanced imaging and monitoring techniques
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