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“Brachytherapy”, also called “Internal radiation therapy”, represents an advanced approach within the realm of radiation therapy, a cornerstone of cancer treatment. Unlike conventional external beam radiation therapy, which emanates radiation from a machine outside the body, brachytherapy involves placing radioactive particles or sources directly inside or adjacent to the tumor site.
By doing so, brachytherapy delivers a targeted, high dose of radiation precisely to the tumor, while minimizing exposure to surrounding healthy tissues. This focused delivery allows for the administration of high radiation doses to specific areas of the body, enhancing treatment efficacy.
This therapy finds application in the treatment of various cancers, including cervical, prostate, breast, skin, lung, head and neck, and gum cancer, among others. Particularly, it is a widely utilized procedure for prostate cancer treatment, offering an alternative to surgery for gum cancer patients who may be unfit or do not require surgical intervention. One of the notable advantages of brachytherapy lies in its efficiency, as treatment completion often requires fewer sessions compared to conventional radiotherapy techniques. Moreover, many patients undergo brachytherapy on an outpatient basis, further enhancing its accessibility and convenience. Overall, brachytherapy is well-tolerated by patients, with fewer side effects reported, making it a valuable therapeutic option in the fight against cancer.
Types of Brachytherapy
There are two types of brachytherapy treatment:
Temporary brachytherapy: In this method, highly radioactive particles are placed in a catheter or slender tube for a specific amount of time and then withdrawn. Temporary brachytherapy can be administered at either a low-dose rate (LDR) or a high-dose rate (HDR).
Permanent brachytherapy: In this method, a radioactive seed or pellet is implanted in or near the tumor and left there permanently. After several months, the radioactivity level of the implanted seed eventually diminishes to nothing.
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IRCCS Ospedale San Raffaele
milan, Italy
- Premier multi-speciality research hospital specialising in molecular medicine, gene therapy, and cardiovascular care.
- Part of Gruppo San Donato (GSD) and affiliated with Università Vita-Salute San Raffaele.
- Treats around 1.5 million patients annually, including many international visitors.
- Designated as a European Reference Centre (ERN GUARD-Heart) for complex heart conditions.
- Offers advanced services in cardiac surgery, electrophysiology, oncology, urology, gene therapy, plastic surgery, and diagnostic imaging.
- Equipped with state-of-the-art operating theatres, diagnostic labs, and 1,640 patient beds.
- Provides multilingual support, patient-focused care, and on-site pharmacies, labs, and cafeterias.
- Ranked among the World’s Best Specialised Hospitals (2025) for cardiology and cardiac surgery.
Casa di Cura La Madonnina
milan, Italy
- Casa di Cura La Madonnina is a renowned multidisciplinary private clinic in Milan, Italy. It provides premium healthcare services with a focus on advanced diagnostics, personalised care, and surgical excellence. The clinic offers state-of-the-art operating rooms, luxury patient rooms, and an exclusive patient experience for both Italian and international patients. It is recognised for its expertise in fields such as fertility and IVF, cardiology, plastic surgery, and digestive endoscopy.
- It integrates clinical excellence with a high standard of comfort and privacy, making it one of the most prestigious private healthcare institutions in Italy.
IRCCS Ospedale Galeazzi- Sant’Ambrogio
milan, Italy
- IRCCS Galeazzi Hospital – Sant’Ambrogio is a leading multidisciplinary hospital located in Milan, Italy. It is internationally renowned for its excellence in orthopaedics, cardiovascular care, and advanced minimally invasive surgery. The hospital features cutting-edge diagnostic technology and state-of-the-art surgical facilities. It is part of the San Donato Hospital Group, combining research, innovation, and high-quality patient care.
- Recognised since 2006 as an IRCCS for research in locomotor system diseases.
- It combines high‑quality clinical care with translational and basic research in orthopaedics, biomechanics, regenerative medicine, etc.
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