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CAR-T Cost in Turkey

Costs starts from USD25000 to USD55000
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How Much Does CART Cost in Turkey?

The cost of a CART in Turkey typically ranges between USD 25000 - USD 55000. However, this cost can vary depending on several factors, including the type and severity of the condition, treatment techniques chosen, the healthcare facility's location and reputation, the treating professionals' experience and specialization, and the patient's overall health status.

Additionally, factors like the duration of treatment, the need for follow-up care, and the use of advanced technologies or specialized treatments can further influence the overall cost.

Factors Influencing the Cost of CART:

CART is an acronym for a promising experimental type of cancer treatment called Chimeric Antigen Receptor T-cell therapy and mainly targets blood malignancies such as leukemia and lymphoma. This therapy is done by modifying the patient’s T-cells (one form of white blood cells) in the laboratory and making them have a receptor that homes in on cancerous cells. These engineered T-cells are then transduced back into the patient, they go on to hunt for cancer cells to kill.

CART therapy is rather effective, particularly in the cases of the treatment efficacy of which has not been rather impressive. It is individual treatment, which means that is independent of the cancer type in the patient. There are risks for cytokine release syndrome (CRS), as well as neurotoxicity that should be closely watched out for, but this option is hopeful for cancer patients who normally cannot be treated with conventional treatments.

Cost of CAR-T in Major Cities of Turkey

CityMinimum Cost (USD)Minimum Cost (TRY)Maximum Cost (USD)Maximum Cost (TRY)
AnkaraUSD 25000976500USD 550002148300
IstanbulUSD 25000976500USD 550002148300
IzmirUSD 25000976500USD 550002148300
SamsunUSD 25000976500USD 550002148300
TokatUSD 22500878850USD 495001933470

CAR-T Cost : A Global Comparison

CountryMinimum CostMinimum Local CurrencyMaximum CostMaximum Local Currency
Czechiaget request
IndiaUSD 80000INR 6851200USD 120000INR 10276800
LithuaniaUSD 300000LTL 1026210USD 500000LTL 1710350
MalaysiaUSD 75000MYR 318000USD 125000MYR 530000
Saudi ArabiaUSD 373000SAR 1398750USD 500000SAR 1875000
Singapore - - USD 475000SGD 612750
SpainUSD 30000ESP 4411197USD 56000ESP 8234234
SwitzerlandUSD 373000CHF 309590USD 500000CHF 415000
ThailandUSD 150000THB 4906500USD 470000THB 15373700
TunisiaUSD 100000TND 298000USD 200000TND 596000
TurkeyUSD 25000TRY 976500USD 55000TRY 2148300
United Arab EmiratesUSD 200000AED 734000USD 300000AED 1101000
United KingdomUSD 373000GBP 276020USD 475000GBP 351500

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CAR T-cell therapy represents a groundbreaking approach to harnessing the power of the body's immune system to combat cancer. By modifying T cells, a subset of white blood cells, in a laboratory setting, these cells are empowered to recognize and eliminate cancer cells with precision. Often categorized as a form of cell-based gene therapy, CAR T-cell therapy involves altering the genetic makeup of T cells, equipping them with the ability to target specific cancer antigens.

This innovative treatment has demonstrated remarkable efficacy, particularly in cases where conventional therapies have proven ineffective. Its ability to reprogram the immune system to target and destroy cancer cells marks a significant advancement in cancer treatment strategies.

Classification:

CAR T cell therapy is classified as follows:

  • Structure-based classification:
  • First-generation CAR T-cells: These CAR T-cells typically consist of an antigen-binding domain (single-chain variable fragment, scFv) linked to a T-cell activation domain, such as the CD3ζ chain. They lack additional co-stimulatory domains.
  • Second-generation CAR T-cells: These CAR T-cells include an additional co-stimulatory domain, such as CD28 or 4-1BB (CD137), along with the CD3ζ chain. The presence of co-stimulatory domains enhances T-cell activation and persistence.
  • Third-generation CAR T-cells: These CAR T-cells incorporate two co-stimulatory domains along with the CD3ζ chain, aiming to further enhance T-cell function and anti-tumor activity.

Antigen-based classification: It includes

  • CD19-targeted CAR T-cells: CD19 is a common target for CAR T-cell therapy and is used in the treatment of B-cell malignancies such as acute lymphoblastic leukemia (ALL) and certain types of lymphoma.
  • Other antigen-targeted CAR T-cells: CAR T-cells can be engineered to target a variety of antigens expressed on cancer cells, including but not limited to BCMA (B-cell maturation antigen), CD22, CD30, and EGFRvIII.

CAR T-cell therapy is primarily used to treat blood cancers, such as multiple myeloma, large B-cell lymphoma, and B-cell acute lymphoblastic leukaemia. The patient's own T cells are reprogrammed to identify and destroy cancer cells, cause remission, enhance survival, and have a plan B in case other treatments fail.

Patients with blood cancers who relapsed or are refractory must consult an oncologist to determine candidacy for CAR T therapy, especially if they have failed to respond to traditional treatments (i.e., chemotherapy, radiation, or stem cell transplant). Evaluation is warranted for symptoms such as loss of weight, swelling of lymph nodes, recurrent infection, chronic fatigue, or spontaneous bruising.

Screening tests consist of imaging, bone marrow biopsy, and blood work.Leukapheresis is utilised to harvest T cells from the patient's blood for T-cell collection.Bridging therapy: Certain patients receive chemotherapy while waiting for CAR T cells to be produced.Lymphodepleting chemotherapy is administered before the injection to make room for CAR T cells. The patients should plan for potential hospitalisation, designate caretakers, and discuss long-term follow-up and expected adverse effects with the medical team.

  • T-cell harvesting: T cells are removed from the patient's blood by processing.
  • Genetic alteration: T cells are designed in the laboratory to express CAR proteins targeting cancer cells.
  • Expansion: Modified T cells are expanded to therapeutic levels.
  • Infusion: Patient receives an intravenous infusion of CAR T cells.
  • Monitoring: Intensive monitoring, often in the hospital, for side effects and reactions.

The whole process, from cell harvesting to infusion, can take three to six weeks. The infusion itself takes a few hours to a few minutes, but for at least one week following the infusion, close monitoring is required, and there will be frequent follow-ups for several months.

  • Cytokine Release Syndrome (CRS)
  • Neurotoxicity
  • Infections
  • Low blood counts
  • Relapse or non-response

One of the newer treatment options for some blood cancers is CAR T-cell therapy. It is utilised when other treatments are not working or the cancer recurs. CAR T-cell therapy has the potential to cure many blood cancers and extend life in most cases.

Recovery involves managing side effects like CRS and neurotoxicity, monitoring blood levels, and avoiding infections. Laboratory testing, imaging, and monitoring for late issues like hypogammaglobulinemia or relapse are all included in long-term follow-up.

The nature of the cancer, the burden of the disease, and an individual's response all impact success. For example, in pediatric acute lymphoblastic leukaemia, complete remission rates are more than 80%. However, relapse is always a risk, and long-term success is variable.

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Explore Hospitals ( 6 )
CAR-T in Medipol Bahçelievler Hospital: Costs, Top Doctors, and Reviews

Istanbul, Turkey

  • Joint Commission International, or JCI

Medipol Bahcelievler Hospital is a medical institution providing a full range of medical and individualized approaches to its patients. Medipol has the ambition to bring high quality and maximum security to people in need by employing state-of-the-art technologies in medicine. They ensure that the health of the patients is improved by fashioning unique physician specialty treatment programs.

Medipol Bahcelievler Hospital provides an exceptional position in the healthcare industry with a policy of clear communication, professionalism, and reliability to patient expectations. Medipol Bahçelievler Hospital is situated in the European Side of Istanbul, dedicated to 24-hour health care for you and your loved ones, equipped with a fully functional operation theatre and ICUs with state-of-the-art equipment, laboratory, emergency, and advanced treatment rooms

CAR-T in VM Medical Park Ankara: Costs, Top Doctors, and Reviews

Ankara, Turkey

  • Joint Commission International, or JCI

Types of CAR-T in VM Medical Park Ankara and its associated cost

Treatment OptionApproximate Cost Range (USD)Approximate Cost Range (TRY)
CAR-T73817 - 1032642238558 - 3003734
  • Address: Kent Koop Mah., Medical Park Ankara Hastanesi, 1868. Sok., Batkent/Yenimahalle/Yenimahalle/Ankara, Turkey
  • Facilities related to VM Medical Park Ankara: Online Doctor Consultation, Post operative followup, Mobility Accessible Rooms, Rehabilitation, Air Ambulance
CAR-T in Medical Park Tokat Hospital: Costs, Top Doctors, and Reviews

Tokat, Turkey

  • Joint Commission International, or JCI

Types of CAR-T in Medical Park Tokat Hospital and its associated cost

Treatment OptionApproximate Cost Range (USD)Approximate Cost Range (TRY)
CAR-T74303 - 1015072162322 - 3029444
  • Address: Yeilrmak, Medical Park Tokat Hastanesi, Vali Zekai G
  • Facilities related to Medical Park Tokat Hospital: Health Insurance Coordination, Mobility Accessible Rooms, Private Rooms, Religious Facilities, Nursery / Nanny Services
CAR-T in VM Medical Park Samsun Hospital: Costs, Top Doctors, and Reviews

Samsun, Turkey

  • Joint Commission International, or JCI

Types of CAR-T in VM Medical Park Samsun Hospital and its associated cost

Treatment OptionApproximate Cost Range (USD)Approximate Cost Range (TRY)
CAR-T73812 - 1033542161333 - 3076349
  • Address: Cumhuriyet, Medical Park, 39. Sokak, Atakum/Samsun, Turkey
  • Facilities related to VM Medical Park Samsun Hospital: Online Doctor Consultation, Post operative followup, Mobility Accessible Rooms, Rehabilitation, Air Ambulance
CAR-T in Ekol: Costs, Top Doctors, and Reviews

Izmir, Turkey

  • ISO 9001

Ekol Hospitals, located in Izmir, Turkey, offers a revolutionary approach to healthcare with its unique integrated model. The hospital is made up of two general hospitals and three specialized medical centers, boasting a total of 250 beds. With a team of 130 highly qualified surgeons and over 500 healthcare professionals, Ekol Hospitals is equipped with state-of-the-art technology to provide exceptional care. The hospital’s Health and Rehabilitation Centre, which was acquired from a hotel space, ensures a comfortable and convenient environment for patients, offering both excellent medical services and access to local attractions. Ekol Hospitals proudly serves a diverse international clientele, with medical staff fluent in English, German, French, and Turkish, and offers competitively priced treatment options. Accredited by respected global agencies, Ekol Hospitals is committed to delivering top-tier healthcare to patients from around the world.

CAR-T in Medstar Antalya Hospital: Costs, Top Doctors, and Reviews

Ankara, Turkey

  • Joint Commission International, or JCI
  • Medstar Antalya Hospital has been providing patients with modern medical services since 2009.
  • It is part of the trusted Memorial Health Group, which is known for expert healthcare in Turkey.
  • The hospital is situated on a large campus and features advanced medical equipment and facilities.
  • It has 124 comfortable beds for patients and five fully prepared operating rooms for surgeries.
  • There are 33 intensive care beds, including specialised units for newborns who require additional support.
  • The hospital treats many health issues like cancer, heart problems, brain conditions, and more.
  • Modern machines, such as MRI, CT, and PET-CT, help doctors identify and treat problems quickly and safely.
  • Medstar meets international safety and care standards and is trusted by both local and global patients.
  • Care plans are made specially for each person, and emotional well-being is also supported.
  • Its location in Antalya makes it easy to reach and ideal for people coming from other countries for treatment.

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Process Involved for CAR-T in Turkey

  • Preoperative Stage: An assessment of the patient's medical history, including testing to determine eligibility for CAR-T therapy and identify the target antigen on cancer cells.
  • Treatment Plan Discussion: An oncologist discusses the procedure of CAR-T therapy, including potential dangers, advantages, and side effects.
  • Therapeutic Stage: T-cells are extracted from the patient, modified in the lab to express a chimeric antigen receptor (CAR), and reintroduced into the patient to target and destroy cancer cells.
  • Postoperative Phase: Closely monitor for side effects. Follow-ups are scheduled regularly to check the response and treat any complications.
  • Cancer patients, especially those suffering from blood cancers like leukemia, lymphoma, and multiple myeloma.
  • Patients who have not responded to previous therapies, such as chemotherapy or radiation.
  • Patients in good overall health with a functioning immune system.
  • Individuals who have specific genetic markers that qualify them for CAR-T treatment.
  • Targeted Action: CAR-T treatment specifically targets cancer cells, increasing efficacy while minimising damage to healthy cells.
  • Potential for Remission: Can result in long-term remission, even in people with difficult-to-treat cancer.
  • Minimally Invasive: The treatment consists mainly of an outpatient procedure for T-cell collection, with the therapy provided via infusion.
  • Medical Oncologist
  • Fill out the inquiry form: Fill out the form to provide us with the relevant information about your condition.
  • Consult with Our Healthcare Expert: One of our qualified specialists will contact you for a consultation.
  • Receive a Detailed Treatment Plan: After examining your situation, we will provide you with a detailed treatment plan that includes expert views and cost breakdowns for various choices.
  • Choose your preferred option: Choose the treatment option that suits you the best.

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Frequently Asked Questions

A. There are several best hospitals for CAR-T in Turkey. Some of the most renowned hospitals for CAR-T in Turkey include the following:

  1. Medical Park Gebze Hospital
  2. Medical Park Samsun Hospital
  3. Medical Park Gaziosmanpasa Hospital
  4. Medical Park Tokat Hospital
  5. Medical Park Ankara Hospital
  6. Medical Park Samsun Tip Merkezi

A. The recovery of the patient may vary, depending on several factors. However, on average, a patient is supposed to stay for about 30 days in the country after discharge. This duration of stay is recommended to complete all the necessary follow-ups and control tests to ensure that the surgery was successful.

How much are the other expenses in Turkey apart from the cost of CAR-T?

Apart from the cost of CAR-T, the patient is also required to pay additionally for daily meals and guest house accommodation. These charges start from USD 50 per person.

Which are the best cities in Turkey for CAR-T Procedure?

CAR-T in Turkey is offered in almost all metropolitan cities, including the following:

  • Fethiye
  • Ankara
  • Antalya
  • Istanbul

Q. Which are the best doctors offering Telemedicine for CAR-T in Turkey?

A. It is possible for patients to opt for video telemedicine consultation before they come for CAR-T in Turkey. Some of the surgeons offering this service include the following

A. After the CAR-T takes place, the average duration of stay at the hospital is about 2 days. During the recovery, the patient is carefully monitored and control tests are performed to see that everything is okay. If required, physiotherapy sessions are also planned during recovery in the hospital.

A. The average rating for CAR-T hospitals in Turkey is 3.6. This rating is automatically calculated based on several parameters such as the infrastructure of the hospital, quality of services, nursing support, and other services.

A. There are more than 6 hospitals that offer CAR-T in Turkey. The above-listed clinics are approved to perform the surgery and have the proper infrastructure to handle CAR-T patients. Additionally, these hospitals are known to comply with international standards as well as local legal requirements for the treatment of patients.

A. Some of the top doctors for CAR-T in Turkey are:

  1. Dr. Nadire Kucukoztas
  2. Dr. Feza Yabug Karakayali

A. In Turkey, the price of CAR-T therapy usually varies between USD 25,000 and USD 55,000, which is indicative of the differences in available treatment alternatives and healthcare facilities.

A. The following are the FDA-approved cancer conditions for CAR-T cell therapy:

  • Acute lymphoblastic leukemia (ALL) from B-cell precursor in individuals under 25 years of age
  • Diffused Large-cell B-cell lymphoma (DLBCL)
  • Large B-cell lymphoma of the primary mediastinal
  • Follicle lymphoma developed into large B-cell lymphoma
  • High-grade lymphoma of B cells
  • Activating B-cell lymphoma not otherwise specified (NOS)
  • Lymphoma with mantle cells
  • The tumor of follicular lymphoma
  • Multiple myeloma

A. Usually, you have to have already had a level of care chemotherapy to be qualified for CAR-T cell therapy. CAR-T cell therapy may be appropriate for patients whose disease has relapsed or is resistant to treatment. Patients have to be sufficiently healthy to receive care.

A. No, not all blood cancers can be treated with CAR T-cell therapy:

Blood cancers treated by CAR T-cell therapy include diffuse large B-cell lymphoma, follicular lymphoma, high-grade B-cell lymphoma, mantle cell lymphoma, multiple myeloma, B-cell acute lymphoblastic leukemia (ALL), and primary mediastinal large B-cell lymphoma.

Since every cancer has a unique set of antigens, every CAR T-cell therapy is designed to target a particular kind of cancer antigen. For instance, CAR T-cell treatments for specific forms of lymphoma or leukemia bind to the CD19 antigen; hence, they are ineffective against malignancies that lack the CD19 antigen.

A.

  • Many renowned Turkish hospitals, especially in larger cities like Ankara, Kocaeli, Samsun, and Tokat have set up specialized programs for CAR-T therapy. These hospitals generally have hematology and oncology divisions dedicated to providing modern facilities for cancer treatments.
  • Working with recognized foreign medical institutions, Turkish hospitals often share expertise and offer training. This increases the standard for treatment and yields better outcomes for patients receiving CAR-T therapy.
  • Certain medical facilities offer extensive support services, which are necessary for patients undergoing CAR-T therapy. Long-term follow-up and counseling are two of these services.

A. To make sure you're prepared for the treatment procedure, there are a few crucial actions to take before receiving CAR-T therapy:

  • Discuss the issues that follow with your medical team: Make an appointment for an assessment with your CAR-T medical professional and oncologist. Current medical care and particulars of CAR-T therapy
  • Observe the proper protocols for scans and blood testing: To determine whether you qualify for CAR-T treatment
  • Recognize the Procedure: Find Out How CAR-T Therapy Operates and What to Expect During Treatment
  • Pretreatment: Make sure the most recent version of the patient's medical records is available to the treatment team.
  • Physical Preparation: Addressing Health Issues That Already Exist As advised by your physician, maintain a well-balanced diet and drink enough water.
  • Plan for after treatment: Make follow-up appointments to assess the effectiveness of the medication and address any side effects.

A. Regarding the success rate of CAR-T cell therapy, multiple studies demonstrate the effectiveness of this novel approach is working. The available evidence indicates that the success rate of CAR-T cell therapy for a long-lasting recovery, without further treatment, is between 30% and 40%.

Author

Dr. Vishwas Kaushik

MBBS, MD

5 Years of Experience

Dr. Vishwas Kaushik is a qualified medical professional holding an MBBS from the prestigious Belgorod State University, Russia, with a strong foundation in clinical medicine and healthcare practice. His comprehensive medical training has equipped him with a profound understanding of evidence-based clinical practices, patient-centered care, and the evolving landscape of modern medicine. With a keen interest in medical research and scientific communication, he consistently translates complex clinical concepts into clear, accurate, and accessible content for diverse audiences. His work reflects a deep commitment to advancing medical knowledge, delivering impactful healthcare insights, and bridging the gap between clinical expertise and accessible medical communication.. View More

Reviewer

Dr Prateek Varshney

Surgical Oncologist

15 Years of Experience

Dr. Prateek Varshney is a renowned Surgical Oncologist. He has experience of more than 15+ years in surgical Oncology. He is currently practicing as a consultant at Metro Mass Hospital and Cancer Institute. He was also previously associated as a consultant with Sir Ganga Ram Hospital and as a professor at Gujarat Cancer Research Institute. View More