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CAR-T Cost in Spain

Costs starts from USD30000 to USD56000
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How Much Does CAR-T Cost in Spain?

The cost of CAR-T in Spain is USD 30000 - USD 56000

Additionally, factors like the duration of treatment, the need for follow-up care, and the use of advanced technologies or specialized treatments can further influence the overall cost.

Factors Influencing the Cost of CART:

CART is an acronym for a promising experimental type of cancer treatment called Chimeric Antigen Receptor T-cell therapy and mainly targets blood malignancies such as leukemia and lymphoma. This therapy is done by modifying the patient’s T-cells (one form of white blood cells) in the laboratory and making them have a receptor that homes in on cancerous cells. These engineered T-cells are then transduced back into the patient, they go on to hunt for cancer cells to kill.

CART therapy is rather effective, particularly in the cases of the treatment efficacy of which has not been rather impressive. It is individual treatment, which means that is independent of the cancer type in the patient. There are risks for cytokine release syndrome (CRS), as well as neurotoxicity that should be closely watched out for, but this option is hopeful for cancer patients who normally cannot be treated with conventional treatments.

Cost of CAR-T in Major Cities of Spain

CityMinimum Cost (USD)Minimum Cost (ESP)Maximum Cost (USD)Maximum Cost (ESP)
BarcelonaUSD 300004411197USD 560008234234
MadridUSD 300004411197USD 560008234234
MarbellaUSD 270003970077USD 504007410811
TorreviejaUSD 270003970077USD 504007410811

CAR-T Cost : A Global Comparison

CountryMinimum CostMinimum Local CurrencyMaximum CostMaximum Local Currency
Czechiaget request
IndiaUSD 80000INR 6851200USD 120000INR 10276800
LithuaniaUSD 300000LTL 1026210USD 500000LTL 1710350
MalaysiaUSD 75000MYR 318000USD 125000MYR 530000
Saudi ArabiaUSD 373000SAR 1398750USD 500000SAR 1875000
Singapore - - USD 475000SGD 612750
SpainUSD 30000ESP 4411197USD 56000ESP 8234234
SwitzerlandUSD 373000CHF 309590USD 500000CHF 415000
ThailandUSD 150000THB 4906500USD 470000THB 15373700
TunisiaUSD 100000TND 298000USD 200000TND 596000
TurkeyUSD 25000TRY 976500USD 55000TRY 2148300
United Arab EmiratesUSD 200000AED 734000USD 300000AED 1101000
United KingdomUSD 373000GBP 276020USD 475000GBP 351500

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CAR T-cell therapy represents a groundbreaking approach to harnessing the power of the body's immune system to combat cancer. By modifying T cells, a subset of white blood cells, in a laboratory setting, these cells are empowered to recognize and eliminate cancer cells with precision. Often categorized as a form of cell-based gene therapy, CAR T-cell therapy involves altering the genetic makeup of T cells, equipping them with the ability to target specific cancer antigens.

This innovative treatment has demonstrated remarkable efficacy, particularly in cases where conventional therapies have proven ineffective. Its ability to reprogram the immune system to target and destroy cancer cells marks a significant advancement in cancer treatment strategies.

Classification:

CAR T cell therapy is classified as follows:

  • Structure-based classification:
  • First-generation CAR T-cells: These CAR T-cells typically consist of an antigen-binding domain (single-chain variable fragment, scFv) linked to a T-cell activation domain, such as the CD3ζ chain. They lack additional co-stimulatory domains.
  • Second-generation CAR T-cells: These CAR T-cells include an additional co-stimulatory domain, such as CD28 or 4-1BB (CD137), along with the CD3ζ chain. The presence of co-stimulatory domains enhances T-cell activation and persistence.
  • Third-generation CAR T-cells: These CAR T-cells incorporate two co-stimulatory domains along with the CD3ζ chain, aiming to further enhance T-cell function and anti-tumor activity.

Antigen-based classification: It includes

  • CD19-targeted CAR T-cells: CD19 is a common target for CAR T-cell therapy and is used in the treatment of B-cell malignancies such as acute lymphoblastic leukemia (ALL) and certain types of lymphoma.
  • Other antigen-targeted CAR T-cells: CAR T-cells can be engineered to target a variety of antigens expressed on cancer cells, including but not limited to BCMA (B-cell maturation antigen), CD22, CD30, and EGFRvIII.

CAR T-cell therapy is primarily used to treat blood cancers, such as multiple myeloma, large B-cell lymphoma, and B-cell acute lymphoblastic leukaemia. The patient's own T cells are reprogrammed to identify and destroy cancer cells, cause remission, enhance survival, and have a plan B in case other treatments fail.

Patients with blood cancers who relapsed or are refractory must consult an oncologist to determine candidacy for CAR T therapy, especially if they have failed to respond to traditional treatments (i.e., chemotherapy, radiation, or stem cell transplant). Evaluation is warranted for symptoms such as loss of weight, swelling of lymph nodes, recurrent infection, chronic fatigue, or spontaneous bruising.

Screening tests consist of imaging, bone marrow biopsy, and blood work.Leukapheresis is utilised to harvest T cells from the patient's blood for T-cell collection.Bridging therapy: Certain patients receive chemotherapy while waiting for CAR T cells to be produced.Lymphodepleting chemotherapy is administered before the injection to make room for CAR T cells. The patients should plan for potential hospitalisation, designate caretakers, and discuss long-term follow-up and expected adverse effects with the medical team.

  • T-cell harvesting: T cells are removed from the patient's blood by processing.
  • Genetic alteration: T cells are designed in the laboratory to express CAR proteins targeting cancer cells.
  • Expansion: Modified T cells are expanded to therapeutic levels.
  • Infusion: Patient receives an intravenous infusion of CAR T cells.
  • Monitoring: Intensive monitoring, often in the hospital, for side effects and reactions.

The whole process, from cell harvesting to infusion, can take three to six weeks. The infusion itself takes a few hours to a few minutes, but for at least one week following the infusion, close monitoring is required, and there will be frequent follow-ups for several months.

  • Cytokine Release Syndrome (CRS)
  • Neurotoxicity
  • Infections
  • Low blood counts
  • Relapse or non-response

One of the newer treatment options for some blood cancers is CAR T-cell therapy. It is utilised when other treatments are not working or the cancer recurs. CAR T-cell therapy has the potential to cure many blood cancers and extend life in most cases.

Recovery involves managing side effects like CRS and neurotoxicity, monitoring blood levels, and avoiding infections. Laboratory testing, imaging, and monitoring for late issues like hypogammaglobulinemia or relapse are all included in long-term follow-up.

The nature of the cancer, the burden of the disease, and an individual's response all impact success. For example, in pediatric acute lymphoblastic leukaemia, complete remission rates are more than 80%. However, relapse is always a risk, and long-term success is variable.

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Explore Hospitals ( 8 )
CAR-T in Centro Medico Teknon: Costs, Top Doctors, and Reviews

Barcelona, Spain

  • Joint Commission International, or JCI

Apart from in-detail treatment procedures available, Centro Medico Teknon located in Barcelona, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • 60,000 square meters of area
  • 211 wards
  • International visitors program to manage the patient base
  • Cardiovascular Institute and Oncology Institute as specialised centres
  • Assisted Reproduction availaibility
  • Checkup program
  • Plastic & Reparative surgery capacities

CAR-T in Hospital Quironsalud Barcelona: Costs, Top Doctors, and Reviews

Barcelona, Spain

  • Joint Commission International, or JCI
  • ISO 9001

Apart from in-detail treatment procedures available, Hospital Quironsalud Barcelona located in Barcelona, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • There are more than 50 healthcare specialties in the hospital.
  • It has different kinds of rooms such as over 130 private rooms, 56 suits, and more than 150 consultation rooms.
  • There are more than 14 operation theatres and 1 robotic surgery theatre is also present.
  • Technologically advanced devices are present in the hospital such as 1 linear accelerator, 2 CAT and 3 MRI scanners.
  • Accommodation, flight booking, transfers and interpreters are available.
CAR-T in Hospital Ruber International: Costs, Top Doctors, and Reviews

Madrid, Spain

  • ISO 9001

The Hospital has a wide architectural structure that consists of-

  • 90+ consultation rooms
  • 108+ private rooms
  • 15 suites and 3 royal suites
  • 10+ operation theatres
  • Neuro-Rehabilitation unit
  • Popular Specialties- Epilepsy, Neuropsychology, Neuro-Ophthalmology, Neuro-Oncology, Clinical Neurology, Memory Disorders, Movement Disorders, Neuro-rehabilitation

CAR-T in Jimenez Diaz Foundation University Hospital: Costs, Top Doctors, and Reviews

Madrid, Spain

  • ISO 9001
  • Joint Commission International, or JCI

With about 80,000 m 2 , it is equipped with the highest sanitary technology and offers a wide portfolio of services-

  • Day hospital
  • 11 central operating rooms
  • 3 operating rooms for CMA
  • 6 Delivery rooms
  • 686 beds
  • Ambulatory major surgery
  • Emergencies
  • Pediatric emergency
  • ICU
  • Neonatal ICU
  • External Consultations
CAR-T in Quironsalud Marbella Hospital: Costs, Top Doctors, and Reviews

Marbella, Spain

  • ISO 9001

Apart from in-detail treatment procedures available, Quironsalud Marbella Hospital located in Marbella, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • The hospital is present in an area of 10.500 square meters.
  • A 24- hour emergency service for all kinds of emergency scenarios, even pediatric.
  • There is a specialised radiology department as well as a hemodialysis unit.
  • The hospital also consists of an Intensive Care Unit with a laboratory.
  • Also present are a functional test area with physiotherapy services in addition to functional recovery.
  • Wide network of Insurance partners both national and international.
  • A professionally managed international patient care center.
  • There are more than 25 medical specialties
  • The number of rooms are: 65 plus private rooms, over 14 consultation rooms.
  • There are also more than 5 operation theatres with 2 endoscopy rooms
  • Ultrasound, MRI, CAT scan are also present as per needs and requirements.
CAR-T in University Hospital Quironsalud Madrid: Costs, Top Doctors, and Reviews

Madrid, Spain

  • Joint Commission International, or JCI
  • ISO 9001

Apart from in-detail treatment procedures available, University Hospital Quironsalud Madrid located in Madrid, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • 54,000 square meters is the area of the hospital.
  • It has huge healthcare capacities with an annual number of 300,000 plus consultations and surgical procedures.
  • The hospital has 39 medical as well as surgical disciplines.
  • There are a variety of rooms available in the hospital which includes 235 individual rooms, as many as 57 suites with 4 royal rooms, 14 Intensive Care unit beds, 8 pediatric ICU beds and 18 Neonatal ICU beds.
  • There are over 70 out-patient clinics present in the hospital.
  • Quironsalud Madrid University Hospital, Madrid has 21 advanced operation rooms.
  • It also possesses one da Vinci surgical robot.
  • The international patient care of the hospital is top notch.
CAR-T in Dexeus University Hospital: Costs, Top Doctors, and Reviews

Barcelona, Spain

  • Joint Commission International, or JCI

Apart from in-detail treatment procedures available, Dexeus University Hospital located in Barcelona, Spain has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:

  • There are more than 450 medical professionals working in Dexeus University Hospital, Barcelona, Spain.
  • Facilities include 4 royal suites, 166 single rooms, 13 operating theatres, 564 parking spaces, 5 delivery rooms, day hospital, 140 consultation rooms.
  • The very latest technological and functional equipment and treatment applications.
  • Technological equipment include 1 CAT scanner, 1 PET-CT scanner, 3 MRI scanners, 10 ultrasound machines, 2 neurosurgery surgical microscopes, and 14 operating tables.
  • Care services include Obstetrics area with 24-hour emergency care service, Neonatology Unit and Level III Neonatal ICU, Lung Cancer Early Diagnosis Programme, Rehabilitation and Physiotherapy, Epilepsy Advanced Diagnosis and Emergency Surgery Unit, Congenital Cardiopathy, Growth Disorders and Intensive Care Unit (ICU).
  • Personalised treatment of patients is available.
  • Focus on research based treatment processes and academics.
  • Main international insurance companies are available to provide the best options to the patients.
  • Multilingual personalised care available for patients per their needs and requirements.
CAR-T in Quironsalud Torrevieja Hospital: Costs, Top Doctors, and Reviews

Torrevieja, Spain

  • ISO 9001

Quironsalud Torrevieja Hospital located in Torrevieja (Alicante), Spain is accredited by ISO. Also listed below are some of the most prominent infrastructural details:

  • The national and international partners of Quironsalud Torrevieja Hospitalmake it a healthcare centre of excellence.
  • The technological upgrades in the hospital have made it the choice of patients in specialties such as Nephrology, Neurology, Orthopedics, Cardiac surgery etc.
  • There are over 35 medical specialties in the hospital.
  • The number of private rooms in the hospital are more than 70 and 45 plus consultation rooms and more than 6 operation theatres.
  • The number of suites are 4 suites and there are 4 royal suites.
  • Ultrasound machines, linear accelerators and even PET-CT, MRI, CAT scan options are present.

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Process Involved for CAR-T in Spain

  • Preoperative Stage: An assessment of the patient's medical history, including testing to determine eligibility for CAR-T therapy and identify the target antigen on cancer cells.
  • Treatment Plan Discussion: An oncologist discusses the procedure of CAR-T therapy, including potential dangers, advantages, and side effects.
  • Therapeutic Stage: T-cells are extracted from the patient, modified in the lab to express a chimeric antigen receptor (CAR), and reintroduced into the patient to target and destroy cancer cells.
  • Postoperative Phase: Closely monitor for side effects. Follow-ups are scheduled regularly to check the response and treat any complications.
  • Cancer patients, especially those suffering from blood cancers like leukemia, lymphoma, and multiple myeloma.
  • Patients who have not responded to previous therapies, such as chemotherapy or radiation.
  • Patients in good overall health with a functioning immune system.
  • Individuals who have specific genetic markers that qualify them for CAR-T treatment.
  • Targeted Action: CAR-T treatment specifically targets cancer cells, increasing efficacy while minimising damage to healthy cells.
  • Potential for Remission: Can result in long-term remission, even in people with difficult-to-treat cancer.
  • Minimally Invasive: The treatment consists mainly of an outpatient procedure for T-cell collection, with the therapy provided via infusion.
  • Medical Oncologist
  • Fill out the inquiry form: Fill out the form to provide us with the relevant information about your condition.
  • Consult with Our Healthcare Expert: One of our qualified specialists will contact you for a consultation.
  • Receive a Detailed Treatment Plan: After examining your situation, we will provide you with a detailed treatment plan that includes expert views and cost breakdowns for various choices.
  • Choose your preferred option: Choose the treatment option that suits you the best.

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Frequently Asked Questions

The average cost of CAR-T in Spain starts from USD 375000 CAR-T in Spain is conducted across several JCI, OHSAS certified hospitals.

The CAR-T package cost in Spain varies from one hospital to another and may offer different benefits. The top hospitals for CAR-T in Spain covers all the expenses related to the pre-surgery investigations of the candidate. The treatment cost usually includes the expenses related to hospitalization, surgery, nursing, medicines, and anesthesia. Stay outside the package duration, post-operative complications and diagnosis of a new condition may further increase the CAR-T cost in Spain.

CAR-T in Spain is offered by multiple hospitals across the country. For quick reference, the following are some of the leading hospitals for CAR-T in Spain:

  1. Hospital Ruber International
  2. Dexeus University Hospital
  3. Quironsalud Barcelona Hospital
  4. Quironsalud Madrid University Hospital
  5. Quironsalud Torrevieja Hospital
  6. Jimenez Diaz Foundation University Hospital

The recovery of the patient many vary, depending on several factors. However, on an average, patient is supposed to stay for about 30 days in the country after discharge. This is important to ensure that the surgery was successful. During this time, control and follow-up tests take place to check for medical fitness.

Apart from the CAR-T cost, the patient may have to pay for additional daily expenses such as for guest house after discharge and meals. These charges starts from USD 50 per person.

Some of the cpopular cities in Spain that offer CAR-T include the following:

  • Barcelona
  • Marbella
  • Madrid
  • Torrevieja

There are many CAR-T surgeons who offer video telemedicine consultation to patients who need this treatment. Some of them include the following:

DoctorCostSchedule Your Appointment
Dr. Juan CarlesUSD 758Schedule Now
Dr. Raimon MirabellUSD 758Schedule Now

The patient has to spend about 2 days in the hospital after CAR-T for proper recovery and to get clearance for discharge. During the recovery, the patient is carefully monitored and control tests are performed to see that everything is okay. If required, physiotherapy sessions are also planned during recovery in hospital.

There are more than 8 hospitals that offer CAR-T in Spain. These hospitals have proper infrastructure for the treatment of patients who require kidney transplant. Apart from good services, the hospitals are known to follow all standard and legal guidelines as dictated by the local medical affairs body or organization.

Author

Dr. Vishwas Kaushik

MBBS, MD

5 Years of Experience

Dr. Vishwas Kaushik is a qualified medical professional holding an MBBS from the prestigious Belgorod State University, Russia, with a strong foundation in clinical medicine and healthcare practice. His comprehensive medical training has equipped him with a profound understanding of evidence-based clinical practices, patient-centered care, and the evolving landscape of modern medicine. With a keen interest in medical research and scientific communication, he consistently translates complex clinical concepts into clear, accurate, and accessible content for diverse audiences. His work reflects a deep commitment to advancing medical knowledge, delivering impactful healthcare insights, and bridging the gap between clinical expertise and accessible medical communication.. View More

Reviewer

Dr Prateek Varshney

Surgical Oncologist

15 Years of Experience

Dr. Prateek Varshney is a renowned Surgical Oncologist. He has experience of more than 15+ years in surgical Oncology. He is currently practicing as a consultant at Metro Mass Hospital and Cancer Institute. He was also previously associated as a consultant with Sir Ganga Ram Hospital and as a professor at Gujarat Cancer Research Institute. View More