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Lesionectomy is a specialised brain surgery designed to remove abnormal tissue causing seizures or other neurological issues, especially in patients who do not respond well to medications. It targets specific brain lesions identified through detailed imaging and diagnostic evaluations.
The procedure involves opening a small part of the skull (craniotomy) to access and carefully remove the lesion, with the help of advanced tools like brain mapping and surgical navigation to avoid damage to healthy brain areas.
Lesionectomy can significantly reduce or stop seizures and may also improve cognitive and functional abilities. Recovery depends on the lesion’s location and complexity, and patients are often supported with short-term rehabilitation and ongoing medical follow-up.
A lesionectomy is a type of brain surgery performed to remove abnormal brain tissue (lesions) that are causing seizures or other neurological problems. These lesions may include tumours, vascular malformations, cortical dysplasia, scarring, or other abnormal brain structures. Lesionectomy is often used to treat drug-resistant epilepsy when seizures originate from a well-defined lesion identifiable on brain imaging. By removing the lesion, the surgery aims to reduce or eliminate seizures and preserve surrounding healthy brain tissue.
You should see a neurologist or neurosurgeon if you experience:
- Frequent or uncontrolled seizures, especially if medications are ineffective
- Neurological symptoms such as weakness, vision changes, speech difficulties, or memory problems
- Changes in personality or cognition
- Brain imaging (MRI, CT) that shows a lesion with unclear or suspicious features
Preparation involves a comprehensive evaluation by a multidisciplinary epilepsy or neurology team:
- Neuroimaging: MRI, PET, or CT scans to locate the lesion
- EEG monitoring: To map seizure activity and confirm the lesion as the source
- Neuropsychological testing: To assess memory, language, and cognitive functions
- Functional MRI or brain mapping: To identify areas responsible for vital functions like speech or movement
- Medication review: Some drugs may be paused or adjusted before surgery
- Fasting: Usually required 6–8 hours before the procedure
- Anaesthesia: The patient is placed under general anaesthesia.
- Craniotomy: A portion of the skull is carefully opened to access the brain.
- Navigation and Mapping: Advanced imaging and intraoperative brain mapping guide the surgeon to locate the lesion precisely.
- Lesion Removal: The abnormal tissue is removed, taking care to avoid surrounding healthy or functional areas.
- Closure: The bone flap is replaced, and the scalp is sutured.
A lesionectomy usually takes 2 to 6 hours, depending on lesion size, location, and complexity. Patients typically stay in the hospital for 3 to 7 days for observation and early recovery.
Although lesionectomy is generally safe, potential risks include:
- Infection
- Bleeding
- Brain swelling
- Neurological deficits (speech, memory, or motor issues, depending on location)
- Seizures after surgery
- Cerebrospinal fluid leakage
- Anesthesia-related complications
- Seizure reduction or elimination, especially in drug-resistant epilepsy
- Improved quality of life, cognitive function, and independence
- Minimal disruption to the surrounding brain tissue when precisely targeted
- Increased effectiveness of medications post-surgery, if still required
- It can sometimes eliminate the need for lifelong anti-seizure medication
After surgery:
- Patients are initially monitored in the ICU and then transferred to a regular neurology unit.
- Headaches, fatigue, or confusion are common during early recovery.
- Physical, occupational, or speech therapy may be needed depending on outcomes.
- Most patients resume light activities in 2 to 4 weeks and return to work or school within 6 to 8 weeks.
- Follow-up includes neuroimaging, EEGs, and ongoing neurology consultations.
Lesionectomy has a high success rate, especially in patients with focal epilepsy and identifiable lesions. Studies show that 60–80% of patients become seizure-free after surgery, and many experience improved cognitive and psychological function.
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NMC Royal Hospital, Khalifa City
Abu Dhabi, United Arab Emirates
NMC Royal Hospital, Khalifa City located in Abu Dhabi, United Arab Emirates is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- Capacity for 500 beds
- 53 Critical Care beds
- 24-hour Emergency Services
- 24-hour Ambulance Service
- OPD (Outpatient department treatment)
- An Automated Laboratory
- The Hospital has the first hybrid Operating Theatre with flex move system
- First NICU and PICU Combination set up
LLH Hospital, Abu Dhabi
Abu Dhabi, United Arab Emirates
3.0 ( 2 Reviews )
LLH Hospital, Abu Dhabi located in Abu Dhabi, United Arab Emirates is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- 24*7 Pharmacy
- 24*7 Emergency DepartmentAmbulance Services
- Mobile Clinics
- Telemedicine
- Valet Parking
- Facility Management Department, which includes dedicated staff responsible for the maintenance of LLH Hospital
Burjeel Hospital, Abu Dhabi
Abu Dhabi, United Arab Emirates
Burjeel Hospital, Abu Dhabi located in Abu Dhabi, United Arab Emirates is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- 209 bed capacity 14-beds in the Intensive Care Unit
- 64 Slice CT, High End MRI, Neuro-navigation Surgical Systems
- 3.0 Tesla MRI
- Neuro-physiology
- Specialized physiotherapy
- Well managed rehabilitation services
- 10 operating theatres
- Royal Suites and Presidential Suites available
- It comprises the most advanced treatment related equipment.
- It is adorned with cutting edge diagnostic equipment.
- Personal attention is given and there is an empathetic approach to healing, the hospital terms it the 'art of healing'.
- Customised services are provided to International patients.
- Centers of excellence
- Cardiology
- Pediatrics
- Ophthalmology
- Oncology
- IVF
- Gynecology & obstetrics
- Orthopedics & sports medicine
- Shoulder and upper limb unit
- Burjeel vascular centre
- Bariatric & metabolic surgery
NMC Specialty Hospital - Al Ain
Abu Dhabi, United Arab Emirates
NMC Specialty Hospital - Al Ain located in Abu Dhabi, United Arab Emirates is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- Capacity for more than 82 beds
- 7 Intensive Care beds
- 13 Nursery beds
- A well-equipped laboratory where tests are carried out by a centralized computerized system
- The hospital has tied up with Biomnis, France for rare investigations and tests not available locally
- Radiology Department with cutting-edge technology- a patient friendly open MRI (1.0 tesla), 64-Slice Spiral CT Scanner, 4-D Ultrasound with Color Doppler, Bone Densitometry, Mammogram, and Digital X-Ray systems backed by a fully integrated PACS system
- 24-hour Emergency Clinic
- 24-hour Ambulance Services
- 24-hour New Medical Center Pharmacy
- 100+ Doctors
- 350+ paramedical personnel and nursing staff
Medeor 24X7 International Hospital, Al Ain
Abu Dhabi, United Arab Emirates
Medeor 24X7 International Hospital, Al Ain located in Abu Dhabi, United Arab Emirates is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- All rooms are equipped with necessary amenities like TV, fridge, adjustable beds, telephone, etc.
- Prefabricated Operation Theatres
- Central Sterile Services Department to prevent infections from spreading
- Operation theatres
- Pre and Post-operative wards
- Physical, cultural and spiritual needs have been taken into consideration, with separate waiting areas for men and women
- Diagnostic imaging services with Al Ains one and only 640 Multi Slice CT and separate female radiology department with mammography and bone mineral densitometry
- Separate isolation rooms for patients with infectious disease
- Fully equipped labor rooms for mother & child care
- 24*7 Emergencies
- GP Clinics
- In-house Pharmacies
- Cafeteria/Restaurants
- Valet parking
Burjeel Medical City
Abu Dhabi, United Arab Emirates
The Hospital owns an International Patient Services Team that is responsible to assist international patients with world-class healthcare, transportation arrangement, accommodation facilities, language interpreters, and much more.
Burjeel Medical City (about 1.2 million square facilities)provides 7-star hospitality to its patients. It has the largest facility space bed among all the private hospitals. The Hospital consists of-
- Large waiting areas and consultation rooms
- Spacious lobbies on each floor
- 338 Luxurious Patient Rooms
- 70 Ambulatory Rooms
- Intensive Care Units
- The Hospital comprises various centers, under Burjeel Cancer Institute-
- Breast Center
- Uro-oncology Center
- Surface Malignancy Center (HIPC)
- Head & Oncology Center
- Medical Oncology & Hematology Center and others
NMC Specialty Hospital
Abu Dhabi, United Arab Emirates
NMC Specialty Hospital located in Abu Dhabi, United Arab Emirates is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- 104 Patient Rooms/Wards
- 7 Operating Rooms
- Laboratory endowed with centrally computerized System
- 24-hour Emergency Department
- 24-hour Pharmacy
- 24-hour Ambulance Services
- Radiology Department offering state-of-the-art equipment, including MRI (1.5 Tesla), 64-slice spiral CT Scanner, 4-D Ultrasound with color Doppler, Bone Densitometry, Digital Mammogram with CAD System, and Digital X-Ray Systems with fully integrated PACS
Lifecare Hospital, Musaffah
Abu Dhabi, United Arab Emirates
Lifecare Hospital, Musaffah located in Abu Dhabi, United Arab Emirates is accredited by ISO, JCI. Also listed below are some of the most prominent infrastructural details:
- Inpatient Pharmacy
- Outpatient Pharmacy
- Nursing Department
- Laboratories
- Intensive Care Unit (ICU)
- Neonatal Intensive Care Unit (NICU)
- Rehabilitation Center
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+99Process Involved for Lesionectomy in Abu Dhabi
- Preoperative Evaluation: This includes a neurological exam, EEG, MRI, and sometimes intracranial monitoring to localise the lesion.
- Surgical Planning: Advanced imaging and brain mapping are used to plan a safe and precise lesion removal.
- Surgery (Lesionectomy): The identified brain lesion is surgically removed through a craniotomy.
- Intraoperative Monitoring: Brain function is continuously monitored to protect vital areas of the brain.
- Postoperative Care: Includes observation in the ICU, pain management, and neurological assessments.
- Rehabilitation: This may involve physical, occupational, or speech therapy, depending on the specific brain area affected.
- Follow-up and Monitoring: Conduct long-term follow-up, including imaging and seizure monitoring, to assess outcomes and evaluate the effectiveness of treatment.
- Drug-resistant epilepsy: Lesionectomy is performed when seizures persist despite optimal medication.
- Low-grade gliomas: The surgery removes slow-growing brain tumours that contribute to seizure activity.
- Cortical dysplasia: Abnormal brain tissue responsible for seizures is surgically eliminated.
- Cavernous malformations: These vascular lesions, which cause recurrent seizures, are safely excised.
- Gangliogliomas: Rare tumours made up of nerve and glial cells are removed to help manage epilepsy.
- Dysembryoplastic neuroepithelial tumours (DNETs): Benign brain growths that trigger seizures are taken out.
- Arteriovenous malformations (selected cases): Certain vascular abnormalities linked with seizures are treated surgically.
- Benign brain lesions causing seizures: Non-cancerous brain abnormalities that generate seizures are targeted and removed.
- Hamartomas: These non-cancerous tissue overgrowths are excised when they cause epilepsy.
- Epileptogenic brain tumours: Tumours acting as a source of seizures are surgically treated.
- Neurological evaluation to confirm seizure origin or lesion-related symptoms.
- Imaging tests, such as MRI, CT scans, and PET scans, are used to locate the lesion accurately.
- EEG or intracranial monitoring to identify abnormal electrical activity.
- Surgical planning using neuronavigation and functional mapping.
- Craniotomy to access the lesion in the brain.
- Precise removal of the abnormal tissue causing seizures or symptoms.
- Intraoperative monitoring is used to ensure the safety of the surrounding brain areas.
- Closure of the surgical site and transfer to recovery or ICU for observation.
- Postoperative imaging to confirm complete lesion removal.
- Ongoing follow-up for seizure control and neurological function evaluation.
- Craniotomy
- Electrocorticography (ECoG)
- Stereoelectroencephalography (SEEG)
- Neuronavigation
- Intraoperative MRI
- Cortical mapping
- Functional MRI (fMRI)
- Brain biopsy
- Intracranial EEG monitoring
- Awake craniotomy
- Seizure control in patients with drug-resistant epilepsy
- Improved quality of life due to reduced or complete seizure freedom
- Preservation of brain function by targeting only the lesion
- Minimally invasive options are available in selected cases
- Faster recovery time compared to extensive brain surgeries
- Reduced medication dependence, often leading to dose reduction or discontinuation
- Accurate diagnosis and treatment, when combined with advanced imaging and monitoring techniques
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