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The average cost of Bone Marrow Transplant in Novena approximately starts from USD 120000 - USD 150000
Cost of Bone Marrow Transplant in Major Cities of Singapore
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A bone marrow transplant is a process that involves harvesting cells for transplantation from the bone marrow which is the spongy tissue found in the cavities of certain bones such as the hip bones. It is also known as Stem Cell transplant. The bone marrow is rich in stem cells, which are capable of developing into various types of blood cells.
The main objective of bone marrow transplantation (BMT) is to transplant healthy bone marrow cells into a patient after the patient's unhealthy bone marrow has been treated to eliminate cancerous cells.
BMT has been used successfully in the treatment of the following diseases such as:
- Aplastic anemia
- Immune deficiency disorders
- Adrenoleukodystrophy
- Bone marrow failure syndromes
- Chronic leukemia
- Hemoglobinopathies
- Hodgkin's lymphoma
- Inborn errors of metabolism
- Multiple myeloma
- Myelodysplastic syndromes
- Neuroblastoma
- Non-Hodgkin's lymphoma
- Plasma cell disorders
- POEMS syndrome
- Primary amyloidosis
There are two main types of bone marrow transplants (BMT), also known as stem cell transplants, based on the source of the stem cells. These are:
- Autologous Transplant (AutoBMT): In an autologous transplant, the patient's stem cells are used for the transplant. Before the transplant, the patient's stem cells are collected, usually from the blood, and freeze. After high-dose chemotherapy or radiation treatment to eliminate diseased cells, the stored frozen stem cells are infused back into the patient. This type of transplant is often used in conditions like multiple myeloma or lymphoma.
- Allogeneic Transplant (AlloBMT): In an allogeneic transplant, the stem cells come from a donor, typically a sibling or unrelated matched donor. Allogeneic transplants are more complex and carry a higher risk of complications, but they can offer a potentially curative treatment for diseases like leukemia, aplastic anemia, or certain genetic disorders.
Autologous BMT treatment is primarily performed for cancers like multiple myeloma, lymphoma, and a few solid tumors. It allows for administering high doses of chemotherapy, which helps the patient restore their healthy bone marrow cells. It is used if the disease is responsive to chemo and a patient's marrow is healthy enough to be harvested and used later.
An initial consultation with a haematologist or oncologist for BMT is warranted if you are diagnosed with a cancer treatable by autologous BMT and have failed conventional treatments or are at high risk of relapse. Otherwise, BMT should be considered if you have persistent symptoms or abnormal blood counts or at the suggestion of your treating oncology team.
Before the procedure begins, you will undergo evaluation for bloodwork and imaging, along with an assessment of organ function. The stem cells will be harvested from your blood via apheresis and stored. Also, depending on your condition, a central line will be placed. It may be recommended that you avoid any infections. Counselling and education before transplants are also part of the procedure.
First, high-dose chemotherapy will be given to kill cancer cells and bone marrow. Next, frozen autologous stem cells are thawed, infused into the bloodstream, travel to the bone marrow, and start regenerating normal blood cells in a sterile hospital environment.
The entire procedure, from stem cell collection to recovery, may continue for weeks. The patient is hospitalised for 2-3 weeks following the procedure and then monitored on an outpatient basis for several months.
- Infection
- Bleeding
- Fatigue
- Mucositis (low blood counts)
- Organ damage
- Graft failure
- Secondary cancers
- Autologous BMT increases survival in certain cancers and allows aggressive chemotherapies that could not be tolerated.
- Immune reconstitution is quicker, generally, and there is no risk of immune rejection.
- It can be a cure or long-term remission for the patients.
The recovery process consists of immune reconstitution and takes several weeks to months. The patient requires watchful follow-up, especially concerning infection control and supportive care such as transfusions. The diet, activity, and hygiene of the patients are carefully observed. Fatigue will continue until it starts to fade away, while strength is returned slowly.
Success rates vary according to disease, but they are usually quite encouraging. Five-year survival rates may vary between 50 and 80%, depending on the type of cancer and the general health status.
Top Selling Packages for Bone Marrow Transplant
Bone Marrow Transplant (Allogenic)
Aakash Healthcare Super Speciality Hospital, Delhi, India
USD 24000 USD 28800
Bone Marrow Transplant (BMT)- Autologus- Lymphoma
Amrita Hospital, Faridabad, India
USD 18000 USD 19000
Bone Marrow Transplant (BMT)- Allogenic- Haplo
Amrita Hospital, Faridabad, India
USD 36000 USD 37000
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Mount Elizabeth Novena Hospital
Novena, Singapore
Mount Elizabeth Novena Hospital located in Novena, Singapore is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- Capacity of 333 beds
- Intensive Care Unit beds
- Endoscopy beds
- Day ward with 20 beds
- 13 Operating Theatres, which includes 1 Neurological operating room, 2 Cardiac operating rooms, 4 Orthopaedic operating rooms, etc.
- High Dependency Unit (HDU)
- Neonatal Intensive Care Unit (NICU)
- 24/7 Accident & Emergency Department
- Maternity ward
- 1 major operating unit with 13 operating rooms inclusive of 1 hybrid theatre
- In-house Pharmacy
- Rooms are categorized as Single Signature Rooms, Junior Suite and Regal Suite
- All patient rooms are equipped with electric safe, LCD, sofa cum bed, wardrobe, radio channels, and much more
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+99Process Involved for Bone Marrow Transplant in Novena
- Preoperative Stage: A thorough examination of the patient's medical history, blood testing, imaging, and tissue compatibility assessments to determine whether they are suitable candidates for BMT.
- Surgical Stage: To eradicate defective bone marrow, the recipient receives chemotherapy or radiation (conditioning therapy), followed by an infusion of donor marrow or stem cells.
- Immediate Postoperative Recovery: Patients are constantly watched for symptoms of infection, graft failure, or complications such as graft-versus-host disease (GVHD), while also receiving supportive care and pain medication.
- Follow-up care: This includes regular check-ups, blood tests, and immune system monitoring to assess marrow engraftment and address any issues that may arise.
- Long-Term Recovery: Recovery may take several months, with continuing monitoring.
- Leukemia
- Lymphoma
- Myeloma
- Aplastic Anemia
- Sickle Cell Disease
- Thalassemia
- Immune Disorders (e.g., Severe Combined Immunodeficiency)
- Donor Consent: Informed consent must be obtained from the donor or their legal next of kin, usually via a donor registry or direct donation agreement.
- Donor Screening: Donors undergo extensive testing for transmissible diseases (e.g., HIV, hepatitis) and compatibility with the recipient.
- Bone Marrow Bank Regulations: To ensure safety and quality, accredited institutions must adhere to strict donor marrow collecting, storage, and distribution guidelines.
- Recipient Evaluation: A complete medical assessment, including genetic and tissue compatibility tests, confirms the recipient's eligibility for transplantation, with all documentation kept.
- Individuals with certain blood malignancies, such as leukemia, lymphoma, and myeloma.
- Patients suffering from noncancerous illnesses such as aplastic anemia, sickle cell disease, or bone marrow immune abnormalities.
- Candidates who haven't responded to previous therapies, including chemotherapy or radiation.
- Chemotherapy/Radiation (conditioning therapy)
- Stem Cell therapy
- Graft-Versus-Host Disease (GVHD) Management
- Immune System Modulation Therapy
- Restores Bone Marrow Function: A successful BMT can restore normal blood cell production, improving general health and quality of life.
- Potential Cure for Blood Disorders: It has the potential to cure some malignancies and blood illnesses that have not responded to previous treatments.
- Improved Quality of Life: BMT can help patients live a more normal life, free of the limitations imposed by blood cell malfunction or cancer treatment.
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- Receive a Detailed Treatment Plan: After examining your situation, we will provide you with a detailed treatment plan that includes expert views and cost breakdowns for various choices.
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