Bone Marrow Transplant in Thailand

Bone marrow transplant, also known as stem cell transplant, is a procedure used to replace the damaged and diseased bone marrow with healthy bone marrow. A bone marrow is a fatty and soft tissue present inside the cells. A bone marrow contains stem cells, which form all the types of cells in the body. The bone marrow produced the blood and in the absence of healthy cells, there is no formation of blood cells, including lymphocytes and red blood cells and thus, the immune system in the body of the patient falls flat.

Bone Marrow Transplant in Thailand

Bone marrow transplant in Thailand is conducted for a variety of purposes. This procedure is used for the treatment of multiple disorders but it is most often carried out in patients suffering from blood cancer. It is used as a part of treatment for conditions such as leukemia, lymphoma, sickle cell anemia, and aplastic anemia. There are several hospitals in Thailand that conduct stem cell transplantation, These hospitals possess all the technology that is used to extract and transplant bone marrow cells.

Bone Marrow Transplantation Cost in Thailand

Bone marrow transplant cost in Thailand depends on several factors. A bone marrow transplant is a complicated procedure. The stem cells that are transplanted into the body of the patient are either retrieved from the body of the patient itself before he or she undergoes chemotherapy or radiation therapy, or they can be retrieved from a suitable donor. In other cases, umbilical cord blood transplant can be performed. Thus, the total cost of stem cell transplant in Thailand depends on the approach used to conduct the procedure, the source of the bone marrow and the total duration of hospitals stay, among several other factors.

Treatment and Cost

20

Total Days
In Country

2 No. Travelers

2 Day in Hospital

18 Days Outside Hospital

Treatment cost starts from

USD 155000

Hospitals

About the Bone Marrow Transplant

Stem cell transplant is one modern technology that is undergoing rapid improvements. It is said these days that instead of investing in various life insurance policies that are making the rounds in the market, to secure the future and precious life of your child go for stem cell technologies. This can later cure him or her from any life threatening terminal disease like cancer. Stem cell transplant has been used in recent times as a cure for cancer, but the technique is different from the stem cell bank that is maintained these days for new born.

 

Who needs a stem cell transplant?

The bone marrow which is part of the bones is responsible for making blood cells. It is soft and spongy tissue lodged inside the bone having hematopoietic stem cells. These cells either turn into bone marrow cells or can turn into any other kinds of cells or the blood cells. But there are certain forms of cancers that can keep these cells from developing normally.

A patient is recommended to get a blood as well as bone marrow stem cell transplant if they are in a condition which prevents the body from producing new healthy blood cells. Some of the conditions and diseases that prevent the bone marrow from doing so are given below:

  • Cancers like Myeloma, breast cancer, leukemia, Lymphoma may require stem cell transplant
  • Blood diseases which may require are sickle cell anemia, aplastic anemia and thalassemia
  • There are immune deficiency diseases like the congenital neutropenia, severe combined immunodeficiency syndrome, chronic granulomatous disease may demand a stem cell transplant.

The oncologist or hematologist shall decide for a stem cell transplant for a patient depending upon overall age and health, severity of the diseases and other treatment possibilities.

 

What is a stem cell transplant?

So the stem cell transplant is a kind of treatment to treat blood disorders or any types of cancer. Even blood diseases are also treated with transplants. Previously patients had to undergo a bone marrow transplant due to the fact that stem cells are collected from the bone marrow. But today stem cells get collected from the blood. And for this particular reason they are now called stem cell transplants. Nowadays stem cell therapies are used to combat hair loss and many other aesthetic related issues.

Some of the different types of stem cell treatments available are discussed below

Autologous transplant: These kinds of transplants are known as auto transplant. This kind of transplant has the scope  of very high dose chemotherapy paired with autologous stem cell rescue. In this process usually the doctors treat the cancel and then make use of the stem cells from the patient itself. From the blood, stem cells are collected and the health care team then freezes it. These cells are usually placed back in the blood after thawing them in the frozen state post the chemotherapy. The cells take almost 24 hours to reach the bone marrow and start multiplying to give rise to healthy blood cells.

Allogenic transplantation: This is better known as an allo transplant medically. In this case stem cells are obtained from another individual. But this individual needs to be someone with whom the bone marrow of the patient matches. Due to presence of proteins in white blood cells called the human leukocyte antigens (HLA) it is important that bone marrow matching takes place. The most compatible stem cell donor will have the HLA matching with that of the patient.

But the process of matching can also give rise to a very severe condition named graft versus host disease or GVHD but then it is not very likely. In this kind of a disease the healthy cells obtained from transplantation will start attacking the cells of the patients. In such cases siblings are considered to be the best match. And if they are not available then some other close family member can also work. Once the donor is fixed then the patient starts receiving chemotherapy session with or without radiotherapy. The other person’s stem is then placed in a vein via a tube. These cells unlike the previous ones are not frozen so they can be given immediately after the completion of chemotherapy.

There can be two types of Allo transplantation depending upon the age, condition and the disease that is being addressed:

The first kind is ablative where high dose of chemotherapy is used and in the second kind milder doses of chemotherapy is employed.

When the assigned health care team is unable to find a matched adult donor then are other options that must be considered like the Umbilical cord blood transplant and these days cancer centers all around the globe make use of cord blood.

Parent child transplant and haplotype mismatched transplant: In these kinds of transplants which are commonly employed the match found is 50% instead of 100% and the donor can be a parent, child or brother and sister.

How is Bone Marrow Transplant performed?

The first step in bone marrow transplant is to reduce the tumour so that the stem cell transplant success rate is improved. The process of harvesting stem cells takes around three to four hours, depending on the number of stem cells collected. The entire process may take around three to five days to complete. Blood count is daily monitored during collection of stem cells to ensure that it does not go below the admissible levels in the donor, which may contribute to anaemia.

A catheter is placed in the donor’s arm during the actual stem cell transplant procedure. The catheter is connected to a special machine that separated stem cells from the blood. After extracting the stem cells, the remaining blood is infused back into the donor's body.

 

Stem Cell Harvesting Procedure

The stem cell concentration in the bone marrow is almost 10 to 100 times more than the levels found in peripheral blood. The hip bone is considered to have the greatest amount of marrow in the active state and a large number of stem cells can also be extracted from there.

The process of harvesting the stem cells from the bone marrow is carried out in an operating room. The donor is given either general anaesthesia, an epidural, or spinal anaesthesia.

The surgeon makes a number of punctures over the skin covering the pelvic bone. A special kind of needle attached to a syringe is then inserted through these punctures. The needle penetrates the bone marrow and blood is drawn out along with marrow through the syringe. The process is continued several times to ensure enough numbers of stem cells are collected as required for the transplant. The whole duration can last for a period of one to two hours. The amount of blood and marrow removed will vary according to the weight and concentration of stem cells in the marrow of the donor. At the end of this procedure, the surgeon covers the puncture region with pressure dressing and bandages. The collected cells are filtered to separate fat particles and fragments of bones. The donor is taken to the recovery room where the hospital team checks for signs of pain, bleeding or any other side effects of the procedure. The donor can leave the hospital in a few hours after his or her body has recovered. But in some cases, they may be required to stay overnight for better monitoring.

The hip area of the donor remains sore for a few days and it is important to take medicines as directed to relieve the pain. Until the blood cell counts increase, doctors may suggest iron supplements t to enhance the ability of the bone marrow to replenish blood cells.

 

Stem Cell Transplant Procedure

High dose of chemotherapy is given to the patient immediately after stem cell collection or can even be done at a later stage. Stem cells are injected into the bloodstream of the patient after the completion of high dose chemotherapy. These stem cells travel all the way to bone marrow to start producing new blood cells, which is important as a number of healthy blood cells are lost during high dose chemotherapy.

Recovery from Bone Marrow Transplant

Until the bone marrow is in a position to make sufficient blood cells, the patient is at the risk of contracting infections and diseases. Therefore, the patient is kept in an isolation room following stem cell transplantation to protect him or her from contamination. The stay in isolation room lasts for over a week or until the level of blood cells is back to normal again.

Isolation is more important in the case of allogeneic stem cell transplant than autologous stem cell transplant. This is the reason why some hospitals do not prefer to keep a patient who has had an autologous transplant isolated.

During the recovery period, only one or two visitors are allowed to visit the patient. Those who are already ill should strictly avoid visiting the patient. There are a few hospital who conduct autologous stem cell transplant on an outpatient basis. However, the patient must come for follow-up 0vists regularly for monitoring of their health.

Patient Stories

Frequently Asked Questions

What is the average cost of Bone Marrow Transplant in Thailand?

The cost of a bone marrow transplant in Thailand starts from $55000 and may go up to $90,000 depending on several factors.

The package charges for bone marrow transplant in Thailand is inclusive of the following:

  • Stem cell stimulation and collection
  • Stem cell culture preparation
  • Transplantation procedure
  • The procedure room fee for patient and donor
  • HEPA filtration system
  • Private room stay for the patient for 30 to 45 days
  • Hospital accommodation for the donor for 1 or 2 days
  • Doctor fee
  • Nursing care
  • Medications charges for patient and donor
  • Medical equipment and consumables charges

The package cost is not inclusive of the following charges:

  • HLA screening and matching
  • Any additional charges that are not related to BMT
  • Pre-diagnostic work-up
  • Discharge medicines
  • Follow-up costs
  • Hotel stay and meals
What are the factors affecting the cost of Bone Marrow Transplant in Thailand?

Some of the factors that influence bone marrow transplant cost in Thailand include the following:

  • Type of transplant- autologous, allogenic from matches sibling, allogenic from matching unrelated donor, or haploidentical bone marrow transplantation
  • Type of donor – matching sibling, half-matches parent or sibling, or unrelated donor
  • Bone marrow donor registry cost, if applicable
  • Conditioning required before transplant – chemotherapy and radiation therapy
  • Experience of the specialists
  • The extent of hospital stay
  • Post-operative condition of the patient
  • Underlying medical conditions
  • Complications management
  • Post-operative monitoring and testing
Which are the best hospitals for Bone Marrow Transplant in Thailand?

The following are the best hospitals for bone marrow transplant in Thailand:

  • Vejthani Hospital, Bangkok
  • Phyathai 2 International Hospital
  • BNH Hospital
  • Bumrungrad International Hospital
  • Samitivej Hospital
  • Siriraj Hospital
  • Ramathibodi Hospital
Who are the top hematologists in Thailand for Bone Transplant?

Some of the top hematologists in Thailand for bone marrow transplant include the following:

  • Dr. Chompunut Wongprasert, Bangkok Hospital
  • Dr. Apichai Leelasiri, Vichaiyut Hospital
  • Assoc. Prof. Col. Dr. Wichean Mongkonsritragoon, Bumrungrad International Hospital
  • Dr. Itsara Anongjanya, Vejthani Hospital
  • Dr. Jiranuch Tantirakrot, Bangkok Hospital Pattaya
  • Dr. Potjana Jitawatanarat, Wattanosoth Cancer hospital
  • Dr. Rattaporn Vichitratchaneekorn, BNH Hospital
  • Dr. Udomsak Bunworasate, Bumrungrad International Hospital
What is the success rate of Bone Marrow Transplantation in Thailand?

The overall 1-year survival rate among patients who undergo bone marrow transplant is more than 90 percent.

The success rate of bone marrow transplant depends on a lot of factors, including the following:

  • The disorder or malignancy patient is suffering from
  • The condition of the patient before transplantation
  • Type of bone marrow transplantation
  • Level of monitoring and care being received
  • How well the patient receives the donor stem cells
  • Any underlying medical conditions at the time of transplantation
  • Post-operative complications and unforeseen circumstances
What is the health care infrastructure of Thailand / Why should opt for Thailand as a destination for your medical treatment
Hospitals in Thailand have seen an increase in number in the past few years. One of the many reasons for such surprise growth in the healthcare division can be the development of the public health sector which comprises 9,765 health locations along with 1,002 hospitals. As the Public Hospitals in Thailand are operated by the MOPH (Ministry of Public Health), the Private Hospitals in Thailand are regulated under the Medical Registration Division. The treatments in Thailand are also keeping up with that of other major countries all across the globe. As of 2002, the Thai Government has provided a countrywide general healthcare system that covers 99.5% of the Thai population and ensures high-quality treatments in Thailand and affordable primary medical amenities to each and every citizen of Thailand. In the year 2009, the total national expenditure on healthcare was 4.3% of the GDP of Thailand. Due to such medical advancements in Thailand, the country has become the most preferred medical destination in the world providing wide-ranging medical treatments at highly-reasonable rates at good hospitals in Thailand.
What are the conditions of the hospitals in Thailand? Are they JCI certified? What is the quality of the support staff in the hospitals?
The Joint Commission International (JCI) is a global leader in health care accreditation. JCI accreditation is considered a gold standard in worldwide health care. It provides the most skilled and experienced healthcare professionals in the medical industry, as evaluators of the rigorous international standards in healthcare quality and patient safety. Here are a few JCI certified hospitals in Thailand :
  • Yanhee Hospital
  • Bumrungrad Hospital
  • Bangkok Hospital
  • Chaophya Hospital
  • BNH Hospital
  • Ramkhamhaeng Hospital
  • Vejthani Hospital
  • Bangkok Hospital Phuket
  • Samitivej Sukhumvit Hospital
  • Praram 9 Hospital
  • Chiangmai Ram Hospital
  • Sikarin Hospital
  • Synphaet Hospital
  • Bangkok Hospital Samui
  • Nonthavej Hospital
  • Bangkok Hospital Pattaya
  • Samitivej Srinakarin Hospital
  • Samitivej Sriracha Hospital
Are the doctors/surgeons in Thailand of the best quality?
Thailand is gaining recognition for the quality of its healthcare services after the US magazine CEOWORLD placed Thailand 6th in its 2019 list of countries with the best healthcare systems. Thai doctors gain a lot of skills during their course and this helps them practice effectively. Many doctors and surgeons also visit other countries for training and certification courses to enhance their skills and knowledge. Most doctors are exposed to a public and private healthcare system in order to be able to work in any condition. It is a collective effort from all the professionals to maintain the standard of health and Thailand is doing just that.
What is the process for obtaining a medical visa in Thailand?
Currently, medical tourists To Thailand are allowed in from 34 countries. All visitors must have proof of travel health insurance that covers a minimum of US$100,000 of medical costs incurred in Thailand, including medical costs in the event that they contract COVID-19. Under the CCSA regulations, medical tourists have to arrive by air to ensure effective disease control, not via land border checkpoints. All must have an appointment letter from a doctor in Thailand and entry certificates issued by Thai embassies across the globe. People wanting to visit Thailand for medical procedures need to contact the Thai Embassy in their country to organize the visa and paperwork. Thailand’s major hospitals will provide potential candidates with an appointment letter. Permission for medical tourists to be accompanied by up to three attending persons is intended to allow such patients to have spouses, parents, or assistants in attendance during their treatment in Thailand. However, such persons will have to conform to all the same entry requirements as the medical tourists themselves, including visas and health status.
What support services does MediGence provide in Thailand?
MediGence enables you to plan and manage your medical decisions better. These are some of our services offered:
  • Expert Opinion
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    Based on your choice of destination and other preferences, we provide you multiple options with respect to hospitals and doctors to choose from.
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  • Transparent Treatment Cost and Other Expenses
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  • Visa Assistance
    We provide and help prepare documentation for visa approval and coordinate with the embassy to expedite the visa process.
  • Accommodation Arrangements
    We propose to you a choice of accommodation based on your preference such as long stay, short stay, or luxury properties.
Which are the best cities in Thailand for medical treatment?
Bangkok is the capital of Thailand and the most sought - after destination for healthcare. It has more than 10 of the major hospitals in Thailand. The cost of treatment in Thailand is reasonable here. People tend to spend their recovery time in Bangkok as well as it is a beautiful city to visit as a tourist.

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