Stem Cell Therapy for COPD Treatment

Symptoms and Causes of COPD

Symptoms 

• Breathing problems, especially when doing vigorous activities
• Wheezing
• Tightness in the chest
• A chronic cough that produces clear, white, yellow, or greenish mucus (sputum).
• Respiratory infections are common.
• Energy deficiency
• Weight loss that was unintentional (in later stages)
• Exacerbations of swelling in the ankles, feet, or legs are likely to occur.

Causes 

• Tobacco smoking (most common cause), especially long-term cigarette smoking
• Exposure to fumes from burning fuel for cooking and heating in poorly ventilated homes
• Alpha-1-antitrypsin deficiency (genetics- 1% of people)
• Asthma
• Occupational exposure to dust and chemicals.

Types of COPD conditions treated by Stem cell Therapy

Emphysema:
It is a lung condition that results in shortness of breath.  The air sacs in the lungs (alveoli) are destroyed in persons with emphysema. The inner walls of the air sacs weaken and rupture over time, resulting in bigger air gaps rather than many small ones. This limits the amount of oxygen that reaches your bloodstream by reducing the surface area of your lungs. Long-term exposure to airborne irritants, such as tobacco smoke, marijuana smoking, air pollution, chemical fumes, and dust, is the leading cause of emphysema. Emphysema is occasionally caused by a hereditary lack of a protein that protects the lungs' elastic structures. This condition caused by alpha-1-antitrypsin deficiency is known as alpha-1-antitrypsin deficiency emphysema. Differentiation is the ability of stem cells to transform into any cell in the body. They can be given intravenously and are used to locate damaged tissues around organs. In the case of COPD patients, stem cells can help to rebuild damaged lung tissue and fight emphysema.

Chronic bronchitis:
Bronchitis occurs when the bronchial airways in your lungs become inflamed. This inflammation can result in intense coughing, mucus production, wheezing, chest pain, and shortness of breath. Acute and chronic are the two main categories. Chronic bronchitis is bronchial inflammation that lasts for a long time. It's a common occurrence among smokers. People with chronic bronchitis are more susceptible to lung infections. They also suffer from acute bronchitis, which causes their symptoms to worsen. When utilized on COPD patients, stem cells can help to restore damaged lung tissue and fight emphysema and chronic bronchitis. Stem cells contain anti-inflammatory capabilities that can help

people with chronic bronchitis clear their airways.

Importance of Stem Cell Therapy for COPD Treatment

People with COPD find it more difficult to carry out their typical daily activities as the disease develops, sometimes due to dyspnea. Due to the loss of productivity at work and at home, as well as the costs of medical treatment, there may be a significant financial burden. People with COPD may require further treatment at home or admission to the hospital for emergency care if their symptoms worsen during flare-ups. Flare-ups that are severe can be fatal. Heart disease, osteoporosis, musculoskeletal diseases, lung cancer, depression, and anxiety are all common in people who have COPD.

Both structural damage and chronic inflammation play a role in COPD-related airway obstruction. Inhaled irritants can harm the components of the respiratory system over time, as well as cause inflammation and narrowing of the airways. COPD is still incurable presently. Fortunately, mesenchymal stem cells (MSCs) have the ability to address both of the disease's contributing components. Stem cells are unspecialized cells that, through a process known as 'differentiation,' can transform into any type of cell in the body. When these cells are injected into a patient's body, they move to dead or damaged tissue and orchestrate healing and regeneration.

Eligibility of Stem Cell Therapy for COPD Treatment

Every person who is suffering from any type of COPD condition is considered eligible for stem cell COPD treatment. Some of the criteria on which a patient’s condition is evaluated are-

• Patients in the initial stage of COPD
• People with an end-stage of COPD
• There are several absolute contraindications that can preclude a patient from being considered for a stem cell treatment that is still in the process of figuring out
• The traditional age limit for stem cell transplantation is 65 years
• Older people, and those with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness.

Stem Cell Treatment Protocol used for COPD by GAIA (in association with CEMAB)
COPD treatments are currently aimed at relieving symptoms, preventing complications, and slowing disease progression. COPD has no known cure. Medications that help lessen symptoms and flare-ups are among the options for treatment. These should be used in conjunction with self-care strategies such as a nutritious diet, frequent exercise, and quitting smoking. COPD affects each person differently, and treatment is individualized based on symptoms and the stage of the disease. Everything is reviewed before starting the stem cell treatment for COPD, and a treatment strategy is assigned for a specific condition.

A treatment protocol is a step-by-step strategy for a scientific or medical experiment, procedure, or treatment. It describes what the experiment will do, how it will be done, and why it will be done in clinical trials. With the aforementioned considerations in mind, a team of stem cell experts at CEMAB has developed some of the most effective therapy procedures. The COPD therapy strategy tries to lessen the body's overall levels of chronic low-grade inflammation. The consequences are expected to linger for a long period.

Treatment Protocol-

• Our two-day protocol centers on the intrathecal transplant of stem cells
• A minimum of 120 million cord tissue-derived MSCs (Mesenchymal Stem Cells) are injected intravenously.
• The procedure takes approximately 45 minutes, is minimally invasive, and has very little downtime.
• Patients normally travel home two days following their scheduled appointment.

Advantages of Stem Cell Therapy for COPD Treatment

When utilized on COPD patients, stem cells can help to restore damaged lung tissue and fight emphysema and chronic bronchitis. Stem cells contain anti-inflammatory capabilities that can help people with chronic bronchitis clear their airways. People with COPD may benefit from stem cells because they can help reduce inflammation in the airways, which can help prevent additional damage. constructing new, healthy lung tissue capable of replacing any damaged tissue in the lungs. Following treatment, many patients reported improved lung capacity and the ability to walk again.

While stem cell therapy cannot 'cure' COPD, it can mend damaged tissue while remaining relatively non-invasive. When you consider that current treatment methods may necessitate the use of ventilators or even entire lung transplants, which are both rare and expensive, this new treatment becomes even more appealing. Researchers at the Lung Health Institute discovered that over 82 % who had stem cell treatment saw noticeable improvements in their quality of life in a report titled 'Autologous Stem Cell Therapy & its Effects on COPD.'

Other benefits of Stem cell treatment for COPD, especially from GAIA (in association with CEMAB) via MediGence-

• No hospitalization required
• No surgical intervention
• No delayed recovery
• Long-lasting results without any permanent side effects
• Virtual consultation available before treatment

How To Apply For Stem Cell Treatment for COPD?  Applying for stem cell therapy is very convenient and hassle-free for you through MediGence-

• Step1- Send us an inquiry with relevant details of your condition
• Step2- Our team of experts will validate your case
• Step3- A dedicated patient care manager will be assigned to your case
• Step4- Once validated, you can also avail a teleconsultation with our stem cell specialist

References:

• https://www.healthline.com/health/copd/stem-cell
• https://www.medicalnewstoday.com/articles/stem-cell-therapy-for-copd