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What is Squamous Cell Carcinoma?

Squamous cell carcinoma (SCC) or cutaneous squamous cell carcinoma (CSCC) is the second most frequent type of skin cancer, following basal cell carcinoma. It begins in squamous cells in your outer layer of skin, the epidermis. Squamous cell carcinomas typically develop on sun-exposed skin parts, such as your head, arms and legs. Cancer can also develop in the parts of your body where you have mucous membranes, that is, the inner lining of your organs and body cavities such as in your mouth, lungs and anus.

Types of Squamous Cell Carcinoma

Depending on the location and extent of the cancer in your body, there are various forms of squamous cell carcinoma:

  • Cutaneous: Cancer that simply affects your skin's outermost layer (in situ) or has spread to other body parts.
  • Metastatic cancer is cancer that has spread to areas of the body other than the skin.

What is the Importance of Timely Treatment?

Squamous cell carcinoma (SCC) should be treated early to enhance cure rates, reduce complications, and prevent the cancer from spreading. Early detection allows for more effective therapy, often resulting in less invasive procedures and a better quality of life for the patient. Delaying treatment can cause more aggressive, costly, and less likely to heal cancer.

What are the Common Symptoms of Squamous Cell Carcinoma?

Depending on the location of the cancer, squamous cell carcinoma (SCC) symptoms may differ, but they generally include:

Skin Lesions: A flat, scaly, crusted lesion or a firm, red nodule often seen on sun-shaded areas like the hands, face, ears, or neck.

Bleeding or Ulceration: Bleeding, ulceration, or an unhealing scab is caused by the tumour.

Pain or Tenderness: The affected region becomes painful or tender upon palpation.

Itching or Burning: Itching or burning can be associated with the lesion.

Lumps or Swelling: Lumps can occur in the neck or nearby regions if SCC invades lymph nodes.

Causes and Risk Factors of Squamous Cell Carcinoma

Causes

Squamous cell carcinoma is due to a mutation of the p53 gene. Ultraviolet (UV) light from the sun or indoor tanning beds is the most common cause of mutations of the p53 gene.

Risk Factors

  • Age
  • Weakened Immune System
  • Smoking
  • Fair Skin
  • Human Papillomavirus (HPV) Infection
  • Chronic Skin Conditions
  • Exposure to Chemicals
  • History of Skin Cancer
  • Radiation Exposure

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Latest Research and Technologies in the Treatment of Squamous Cell Carcinoma in Turkey

Recent studies in Turkey show an increasing prevalence of squamous cell carcinoma (SCC), its frequency tending towards that of basal cell carcinoma. Modern treatments are cryotherapy, photodynamic therapy, radiotherapy, excisional surgery, Mohs surgery, and curettage, providing several choices for efficient management.

Squamous Cell Carcinoma Prevention Tips

There are a few tips to prevent squamous cell carcinoma, including:

  • Wear protective clothing such as long sleeves, caps, and sunglasses to protect the skin from the sun.
  • Avoid tanning beds since they expose the skin to dangerous UV rays.
  • Visit a dermatologist for a professional skin checkup and conduct routine skin checks.
  • Quit smoking since it raises the risk of SCC, especially in the lungs, throat, and mouth.
  • Vaccinate yourself against the human papillomavirus (HPV), which has been connected to genital SCC.
  • Avoid exposing your skin to chemicals like arsenic, which might increase your chance of developing SCC.

Treatment options for Squamous Cell Carcinoma

Chemotherapy: kills cancer cells by using potent medications. Chemotherapy can be used either alone or in conjunction with other therapies, such as radiation therapy and targeted therapy if squamous cell carcinoma spreads to the lymph nodes or other areas of the body.


Cost Start From USD 7420 - USD 30000Explore Options

Targeted therapy: Drugs that target particular molecules in cancer cells are used in targeted therapy. Targeted therapies can kill cancer cells by preventing these molecules from functioning. Chemotherapy is typically combined with targeted therapy.


Cost Start From USD 7500 - USD 12000Explore Options

Immunotherapy: It is a treatment that assists the body's immune system in destroying cancerous cells. The immune system targets bacteria and other cells that shouldn't be in the body to fight against illnesses. To survive, cancer cells hide themselves from the immune system. Immunotherapy aids the cells of the immune system in locating and eliminating cancer cells.


Cost Start From USD 7420 - USD 42500Explore Options

Cryosurgery: The process of freezing cancer cells to kill them.

Photodynamic treatment (PDT): Using light-sensitive chemicals and blue light to eradicate skin cancer.

Curettage and electrodesiccation include using a spoon-like tool (curette) to scrape off the malignant lump and then using an electric needle to burn the region.

Excision is the process of removing the cancer from your skin and then stitching it back together.

Mohs surgery: Usually performed for face malignancies, this procedure involves removing cancerous skin layers.

  • Physicalexamination: Besides asking about your medical history, a healthcare team member will examine your skin for signs of squamous cell carcinoma.
  • A biopsy is the process of taking a sample of tissue for analysis. The method of taking a tissue sample for laboratory examination is called a biopsy. Using a tool, a member of your healthcare team will cut, shave, or punch off part or all of the skin that appears abnormal. It is examined in a lab to determine whether the sample is cancerous.

MediRehab (chain of Rehab centres - Part of MediGence) provides comprehensive rehabilitation services rehabilitation services to support patients through Teleconsulations and online therapy sessions.

  • Physical Therapy: Physical therapy may be used to regain strength and mobility if it is damaged by radiation or surgery, particularly after head, neck, or limb surgery.
  • Speech and Swallowing Therapy: If SCC treatment affects the mouth, throat, or neck, speech or swallowing therapy can restore normal function.
  • Depending on the situation, your healthcare professional may prescribe medicine to help control your symptoms and support the treatment plan.

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Hospitals for Squamous Cell Carcinoma in Turkey

Medical Park Fatih Hospital: Top Doctors, and Reviews
Medical Park Fatih Hospital

Istanbul, Turkey

Medical Park Fatih Hospital located in Istanbul, Turkey is accredited by JCI. Also listed below are some of the most prominent infrastructural details:

  • Situated in an area of 6500 m2
  • Capacity of 84 beds
  • Emergency Clinic
  • ICU
  • Many special services, including but not limited to T.V. (all domestic and international canals are available), Internet, patient-specific diet and journals and newspapers, are offered to patients to maximize satisfaction
  • Private rooms for patients available
  • Family accommodation
  • Pharmacy
  • Laundry
  • Mobility accessible rooms
  • Parking lot
  • Prayer Room
  • Cafeteria
Biruni University Hospital: Top Doctors, and Reviews
Biruni University Hospital

Istanbul, Turkey

Biruni University Hospital started to serve in 2016. It is a full-fledged multi-specialty healthcare facility, situated in Istanbul, Turkey. The hospital is well-known for its outstanding medical care standards, and it has acquired numerous certificates from international quality organizations. It is a renowned & well-established healthcare facility that provides cutting-edge diagnostic and treatment approaches. They have a team of highly skilled doctors and surgeons on call 24 hours a day, seven days a week to deliver the best medical care possible.

The hospital has various medical departments such as Cardiology, Neurology, Urology, Rheumatology, Pediatrics, General Medicine and Surgery, Gastroenterology, etc. Popular treatments conducted at the hospital are Pediatric Neurology, Cardiac Stenting, Balloon Angioplasty, Bypass surgery, plastic surgery procedures like Hair transplant, & Botox injections, and many more.  The hospital is known for its most valuable service i.e. service to human health. Hospital management & professionals define their service concept with the significance attached to the belief. The management is concerned with both medical statistics and, above all, the satisfaction of the patients. Patients from other countries are well looked after. The hospital offers international patients a relaxing and secure environment in terms of psychology, comfort, and health.

The hospital's primary purpose is to provide world-class patient-centered health care through our highly responsible team who can produce information and use it appropriately. With its university-based scientific infrastructure and competent health care, the hospital's management has long-term plans for it, with a desire to be an innovative and leading health institution that is regarded as a reference in the country and around the world. Several value-added services and quality policies are available at the facility. To mention a few, the hospital is open to development and technology, continuously measuring and improving, training qualified health professionals, caring about patient and employee satisfaction, and becoming mobilized to bring an environment of reliable diagnosis, treatment, and care to the majority of the society.

Medstar Antalya Hospital: Top Doctors, and Reviews
Medstar Antalya Hospital

Ankara, Turkey

  • Medstar Antalya Hospital has been providing patients with modern medical services since 2009.
  • It is part of the trusted Memorial Health Group, which is known for expert healthcare in Turkey.
  • The hospital is situated on a large campus and features advanced medical equipment and facilities.
  • It has 124 comfortable beds for patients and five fully prepared operating rooms for surgeries.
  • There are 33 intensive care beds, including specialised units for newborns who require additional support.
  • The hospital treats many health issues like cancer, heart problems, brain conditions, and more.
  • Modern machines, such as MRI, CT, and PET-CT, help doctors identify and treat problems quickly and safely.
  • Medstar meets international safety and care standards and is trusted by both local and global patients.
  • Care plans are made specially for each person, and emotional well-being is also supported.
  • Its location in Antalya makes it easy to reach and ideal for people coming from other countries for treatment.

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Why Choose Turkey for Squamous Cell Carcinoma Treatment?

Turkey's advanced medical infrastructure, highly qualified medical personnel, and availability of the newest research and technologies make it an excellent destination for treating squamous cell carcinoma (SCC). For SCC, the top institutions in the US provide state-of-the-art care, including immunotherapy, targeted medicines, and novel surgical alternatives. International clinical trials are also conducted in Turkey, giving patients access to exciting new therapies.

Frequently Asked Questions

Yes, squamous cell carcinoma (SCC) can spread to other body parts if left untreated in its initial stages. It can metastasise to distant sites such as the lymph nodes, lungs, liver, or bones or locally spread to adjacent tissues. Early diagnosis and treatment are essential for a good prognosis since SCC becomes increasingly more challenging to treat when it metastasises.

Following an assessment of these variables, the oncologist will classify the tumour into one of the following phases of squamous cell carcinoma:

Stage 0: Only the epidermis, or the outermost layer of the skin, has cancer.

Stage 1: The cancer has advanced profoundly into the skin, but it hasn't reached any healthy tissues or lymph nodes nearby.

Stage 2: Cancer has not migrated to neighbouring lymph nodes or healthy tissues, but it has deepened into the skin and exhibits one or more high-risk characteristics (such as metastases to nerves or lower skin layers).

Stage 3: Although the cancer has spread to lymph nodes, it has not yet reached any other organs outside the skin.

Stage 4: The disease has progressed to one or more distant organs, including the liver, lungs and part of the skin.

The location, stage, and overall health of the patient are among the factors that influence the survival rate of squamous cell carcinoma (SCC) in Turkey, as elsewhere. The survival rate for localised SCC is typically high, i.e., the cancer has not metastasised outside the original site. The key to better outcomes is early diagnosis and treatment.

Squamous cell carcinoma (SCC) can recur after treatment, mainly if it is advanced or not fully cured. Recurrence is more likely to happen if the patient has a history of skin cancer or if the tumour has spread to lymph nodes or surrounding tissues.

Regular follow-up and monitoring are necessary to detect recurrence symptoms early and initiate the appropriate treatment.

Squamous cell carcinoma (SCC) cannot be transmitted. It cannot be passed from person to person by touch, contact, or commingling surroundings. SCC is a type of skin cancer not caused by bacteria, viruses, or other infectious processes; it arises from injury caused by conditions such as smoking, UV radiation, or specific infection. Environmental exposure and personal habits are generally responsible for the risk factors of SCC.

Yes, you can get a second opinion on Squamous Cell Carcinoma treatment in Turkey through MediGence. With MediGence, you can connect with highly experienced professionals from top Turkish hospitals who can provide additional information regarding your diagnosis and treatment options. The platform facilitates easy access to professional help so you can make informed healthcare choices and receive the best care possible.

To find a certified cancer specialist, search MediGence’s website, which offers a list of top-class and internationally trained oncologists from Turkey's best hospitals. Through MediGence, you can search the profiles of specialists, check their credentials, reviews, and experience, and book online consultations. To get the best care for your condition, the website also assists you in finding the best hospitals and provides personalised assistance for your health requirements.