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What is Squamous Cell Carcinoma?

Squamous cell carcinoma (SCC) or cutaneous squamous cell carcinoma (CSCC) is the second most frequent type of skin cancer, following basal cell carcinoma. It begins in squamous cells in your outer layer of skin, the epidermis. Squamous cell carcinomas typically develop on sun-exposed skin parts, such as your head, arms and legs. Cancer can also develop in the parts of your body where you have mucous membranes, that is, the inner lining of your organs and body cavities such as in your mouth, lungs and anus.

Types of Squamous Cell Carcinoma

Depending on the location and extent of the cancer in your body, there are various forms of squamous cell carcinoma:

  • Cutaneous: Cancer that simply affects your skin's outermost layer (in situ) or has spread to other body parts.
  • Metastatic cancer is cancer that has spread to areas of the body other than the skin.

What is the Importance of Timely Treatment?

Squamous cell carcinoma (SCC) should be treated early to enhance cure rates, reduce complications, and prevent the cancer from spreading. Early detection allows for more effective therapy, often resulting in less invasive procedures and a better quality of life for the patient. Delaying treatment can cause more aggressive, costly, and less likely to heal cancer.

What are the Common Symptoms of Squamous Cell Carcinoma?

Depending on the location of the cancer, squamous cell carcinoma (SCC) symptoms may differ, but they generally include:

Skin Lesions: A flat, scaly, crusted lesion or a firm, red nodule often seen on sun-shaded areas like the hands, face, ears, or neck.

Bleeding or Ulceration: Bleeding, ulceration, or an unhealing scab is caused by the tumour.

Pain or Tenderness: The affected region becomes painful or tender upon palpation.

Itching or Burning: Itching or burning can be associated with the lesion.

Lumps or Swelling: Lumps can occur in the neck or nearby regions if SCC invades lymph nodes.

Causes and Risk Factors of Squamous Cell Carcinoma

Causes

Squamous cell carcinoma is due to a mutation of the p53 gene. Ultraviolet (UV) light from the sun or indoor tanning beds is the most common cause of mutations of the p53 gene.

Risk Factors

  • Age
  • Weakened Immune System
  • Smoking
  • Fair Skin
  • Human Papillomavirus (HPV) Infection
  • Chronic Skin Conditions
  • Exposure to Chemicals
  • History of Skin Cancer
  • Radiation Exposure

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Latest Research and Technologies in the Treatment of Squamous Cell Carcinoma in Turkey

Recent studies in Turkey show an increasing prevalence of squamous cell carcinoma (SCC), its frequency tending towards that of basal cell carcinoma. Modern treatments are cryotherapy, photodynamic therapy, radiotherapy, excisional surgery, Mohs surgery, and curettage, providing several choices for efficient management.

Squamous Cell Carcinoma Prevention Tips

There are a few tips to prevent squamous cell carcinoma, including:

  • Wear protective clothing such as long sleeves, caps, and sunglasses to protect the skin from the sun.
  • Avoid tanning beds since they expose the skin to dangerous UV rays.
  • Visit a dermatologist for a professional skin checkup and conduct routine skin checks.
  • Quit smoking since it raises the risk of SCC, especially in the lungs, throat, and mouth.
  • Vaccinate yourself against the human papillomavirus (HPV), which has been connected to genital SCC.
  • Avoid exposing your skin to chemicals like arsenic, which might increase your chance of developing SCC.

Treatment options for Squamous Cell Carcinoma

Chemotherapy: kills cancer cells by using potent medications. Chemotherapy can be used either alone or in conjunction with other therapies, such as radiation therapy and targeted therapy if squamous cell carcinoma spreads to the lymph nodes or other areas of the body.


Cost Start From USD 7420 - USD 30000Explore Options

Targeted therapy: Drugs that target particular molecules in cancer cells are used in targeted therapy. Targeted therapies can kill cancer cells by preventing these molecules from functioning. Chemotherapy is typically combined with targeted therapy.


Cost Start From USD 7500 - USD 12000Explore Options

Immunotherapy: It is a treatment that assists the body's immune system in destroying cancerous cells. The immune system targets bacteria and other cells that shouldn't be in the body to fight against illnesses. To survive, cancer cells hide themselves from the immune system. Immunotherapy aids the cells of the immune system in locating and eliminating cancer cells.


Cost Start From USD 7420 - USD 42500Explore Options

Cryosurgery: The process of freezing cancer cells to kill them.

Photodynamic treatment (PDT): Using light-sensitive chemicals and blue light to eradicate skin cancer.

Curettage and electrodesiccation include using a spoon-like tool (curette) to scrape off the malignant lump and then using an electric needle to burn the region.

Excision is the process of removing the cancer from your skin and then stitching it back together.

Mohs surgery: Usually performed for face malignancies, this procedure involves removing cancerous skin layers.

  • Physicalexamination: Besides asking about your medical history, a healthcare team member will examine your skin for signs of squamous cell carcinoma.
  • A biopsy is the process of taking a sample of tissue for analysis. The method of taking a tissue sample for laboratory examination is called a biopsy. Using a tool, a member of your healthcare team will cut, shave, or punch off part or all of the skin that appears abnormal. It is examined in a lab to determine whether the sample is cancerous.

MediRehab (chain of Rehab centres - Part of MediGence) provides comprehensive rehabilitation services rehabilitation services to support patients through Teleconsulations and online therapy sessions.

  • Physical Therapy: Physical therapy may be used to regain strength and mobility if it is damaged by radiation or surgery, particularly after head, neck, or limb surgery.
  • Speech and Swallowing Therapy: If SCC treatment affects the mouth, throat, or neck, speech or swallowing therapy can restore normal function.
  • Depending on the situation, your healthcare professional may prescribe medicine to help control your symptoms and support the treatment plan.

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Hospitals for Squamous Cell Carcinoma in Turkey

Acibadem Kadikoy Hospital: Top Doctors, and Reviews
Acibadem Kadikoy Hospital

Istanbul, Turkey

Acibadem Kadikoy Hospital located in Istanbul, Turkey is accredited by JCI. Also listed below are some of the most prominent infrastructural details:

  • The number of beds in the hospital are 138 and Intensive Care beds are 23.
  • There are as many as 6.500 access points for a building control system.
  • There are 10 Operating theatres and more than 500 employees.
  • There are specific healthcare facilities in Acibadem Kadikoy Hospital, Istanbul, Turkey which have been established per integrated healthcare outreach such as Breast Health Center, Check-up Center, and Diabetes Clinic etc.
  • The hospital has the very best of Medical Technologies such as Flast CT, da Vinci robot, Magnetom Area MRI, Greenlight, Ortophos XG 3D and Full Body MRI, 4-Dimensional Breast Ultrasound, 3-Dimensional Tomosynthesis Digital Mammography.
Medipol Bahçelievler Hospital: Top Doctors, and Reviews
Medipol Bahçelievler Hospital

Istanbul, Turkey

Medipol Bahcelievler Hospital is a medical institution providing a full range of medical and individualized approaches to its patients. Medipol has the ambition to bring high quality and maximum security to people in need by employing state-of-the-art technologies in medicine. They ensure that the health of the patients is improved by fashioning unique physician specialty treatment programs.

Medipol Bahcelievler Hospital provides an exceptional position in the healthcare industry with a policy of clear communication, professionalism, and reliability to patient expectations. Medipol Bahçelievler Hospital is situated in the European Side of Istanbul, dedicated to 24-hour health care for you and your loved ones, equipped with a fully functional operation theatre and ICUs with state-of-the-art equipment, laboratory, emergency, and advanced treatment rooms

Florence Nightingale Hospital: Top Doctors, and Reviews
Florence Nightingale Hospital

Istanbul, Turkey

The first green hospital in Turkey, Istanbul Florence Nightingale Hospital, was inaugurated in 2013. Group The Florence Nightingale hospitals are the first Turkish hospitals to be granted Joint Commission International (JCI) accreditation, and they continue to be associated and work with esteemed healthcare organizations.

The Florence Nightingale Group treats 250,000 outpatients and 70,000 inpatients annually, demonstrating its excellence. The hospitals have a capacity of 804 inpatient beds, 141 ICU beds, and 40 operating rooms, and perform 20,000+ procedures annually, of which 1,000 are cardiac operations for children and 2,000 are for adults. For conducting difficult orthopedic, general surgery, minimally invasive, and other heart treatments, the facility stands out. All operating rooms can be interconnected by audio-visual to a 300-person conference room and global hubs, enabling interactive medical teaching and scientific activity.

Interpreter and translator services for languages such as Turkish, Azerbaijani, Bulgarian, Arabic, English, Persian, Serbian, Russian, Albanian, Macedonian, German, Bosnian, and Romanian are available.

The hospital has specialized departments such as Cardiology and Cardiac Surgery, IVF and Infertility, Nephrology, Oncology and Oncosurgery, Spine Surgery, Neurology and Neurosurgery, Orthopedics, Gynecology, and Obesity or Bariatric Surgery. With an extensively qualified and experienced team of advisors and interpreters, Florence Nightingale Istanbul is committed to providing one-stop service from beginning to end, 24 hours a day, 7 days a week.

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Why Choose Turkey for Squamous Cell Carcinoma Treatment?

Turkey's advanced medical infrastructure, highly qualified medical personnel, and availability of the newest research and technologies make it an excellent destination for treating squamous cell carcinoma (SCC). For SCC, the top institutions in the US provide state-of-the-art care, including immunotherapy, targeted medicines, and novel surgical alternatives. International clinical trials are also conducted in Turkey, giving patients access to exciting new therapies.

Frequently Asked Questions

Yes, squamous cell carcinoma (SCC) can spread to other body parts if left untreated in its initial stages. It can metastasise to distant sites such as the lymph nodes, lungs, liver, or bones or locally spread to adjacent tissues. Early diagnosis and treatment are essential for a good prognosis since SCC becomes increasingly more challenging to treat when it metastasises.

Following an assessment of these variables, the oncologist will classify the tumour into one of the following phases of squamous cell carcinoma:

Stage 0: Only the epidermis, or the outermost layer of the skin, has cancer.

Stage 1: The cancer has advanced profoundly into the skin, but it hasn't reached any healthy tissues or lymph nodes nearby.

Stage 2: Cancer has not migrated to neighbouring lymph nodes or healthy tissues, but it has deepened into the skin and exhibits one or more high-risk characteristics (such as metastases to nerves or lower skin layers).

Stage 3: Although the cancer has spread to lymph nodes, it has not yet reached any other organs outside the skin.

Stage 4: The disease has progressed to one or more distant organs, including the liver, lungs and part of the skin.

The location, stage, and overall health of the patient are among the factors that influence the survival rate of squamous cell carcinoma (SCC) in Turkey, as elsewhere. The survival rate for localised SCC is typically high, i.e., the cancer has not metastasised outside the original site. The key to better outcomes is early diagnosis and treatment.

Squamous cell carcinoma (SCC) can recur after treatment, mainly if it is advanced or not fully cured. Recurrence is more likely to happen if the patient has a history of skin cancer or if the tumour has spread to lymph nodes or surrounding tissues.

Regular follow-up and monitoring are necessary to detect recurrence symptoms early and initiate the appropriate treatment.

Squamous cell carcinoma (SCC) cannot be transmitted. It cannot be passed from person to person by touch, contact, or commingling surroundings. SCC is a type of skin cancer not caused by bacteria, viruses, or other infectious processes; it arises from injury caused by conditions such as smoking, UV radiation, or specific infection. Environmental exposure and personal habits are generally responsible for the risk factors of SCC.

Yes, you can get a second opinion on Squamous Cell Carcinoma treatment in Turkey through MediGence. With MediGence, you can connect with highly experienced professionals from top Turkish hospitals who can provide additional information regarding your diagnosis and treatment options. The platform facilitates easy access to professional help so you can make informed healthcare choices and receive the best care possible.

To find a certified cancer specialist, search MediGence’s website, which offers a list of top-class and internationally trained oncologists from Turkey's best hospitals. Through MediGence, you can search the profiles of specialists, check their credentials, reviews, and experience, and book online consultations. To get the best care for your condition, the website also assists you in finding the best hospitals and provides personalised assistance for your health requirements.