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What is Glioma?

Gliomas are tumour growths of cells that arise in the spinal cord or brain. Glioma cells are similar to glial cells, which are healthy brain cells. Glial cells support and encompass nerve cells in their function.

A glioma becomes a tumour, which is a collection of cells. The tumour growth can compress the brain or spinal cord, causing symptoms. The location of the affected part of the brain or spinal cord determines the symptoms.

There are many kinds of gliomas. Some are not considered to be malignancies and develop slowly, while others are considered to be malignancies. Malignant is another term that means cancerous. Malignant gliomas can invade normal brain tissue and grow very quickly. Some gliomas are more prevalent in adulthood, while others only occur in children.

Types of glioma

The type of glial cells from which gliomas develop determines their classification. The main glioma types are as follows:

Astrocytoma: This originates from astrocytes, which are star-shaped glial cells. They consist of low-grade tumours, which are less malignant, and high-grade tumours, which are more malignant.

Oligodendrogliomas: Oligodendrocytes, the cells that originate oligodendrogliomas, form the myelin sheath that envelops nerve fibres. These tumours tend to develop more slowly.

Ependymomas: The ependymal cells lining the ventricles of the brain and spinal cord lead to ependymomas. Adults and children can develop them.

Glioblastoma (GBM) is among the most vicious and lethal of brain tumours and is a highly malignant and aggressive type of astrocytoma.

What is the Importance of Timely Treatment?

Glioma should be treated as early as possible to enhance outcomes and quality of life. Early management can achieve minimal symptoms, reduced tumour growth, and potentially enhanced effectiveness of chemotherapy, radiotherapy, and surgery. Delaying treatment may make the disease more challenging to manage by increasing pressure in the brain, exacerbating neurological deficits, and enhancing tumour growth. Early treatment may improve the options for personalised treatment, which may strengthen long-term survival.

What are the Common Symptoms of Glioma?

The location of a glioma determines its symptoms. The glioma's size, type, and growth rate may also affect the symptoms.

  • Headache, especially one that is most painful in the morning.
  • Vomiting, and nausea.
  • Confusion or deterioration in brain function, including issues with information comprehension and thought processes.
  • Loss of memory.
  • Alterations in personality.
  • Double vision, blurred vision, or loss of peripheral vision.
  • Speech issues.
  • Seizures

Causes and Risk Factors of Glioma

Causes

Studies have shown that gliomas and other spinal cord and brain cancers result from DNA alterations. DNA is found in our genes, which dictate how cells divide and grow. If the DNA of our genes mutates, cells can grow uncontrollably.

Your parents can pass down genetic mutations. They can also co-occur while you're alive.

Risk Factors

  • Age
  • Family history
  • Radiation exposure
  • Environmental factors
  • Weakened immune system

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Latest Research and Technologies in the Treatment of Glioma in Turkey

Current research in Turkey has significantly improved the treatment of gliomas, particularly glioblastoma multiforme (GBM). A trial of 137 GBM patients reported median progression-free and overall survival times of 8.57 and 12 months, respectively, emphasising the importance of improving treatments. Another Turkish study analysed the results of glioblastoma patients after a decade and emphasised the country's commitment to enhancing glioma treatment.

Treatment options for Glioma

Brain Cancer Treatment: Depending on the type, size, and location of the tumour, glioma is usually treated with a combination of chemotherapy, radiation therapy, and surgery.


Cost Start From USD 8650 - USD 29000Explore Options

Surgery: The first step in treating gliomas is typically to remove the tumour. If the glioma is eliminated, surgery may be the only necessary treatment.

Chemotherapy: Chemotherapy medications are used to kill tumour cells. Chemotherapy drugs are usually given intravenously or orally. Chemotherapy may sometimes be given directly to the glioma cells.


Cost Start From USD 7420 - USD 30000Explore Options

Radiation Therapy: Radiation destroys tumour cells with high-energy beams. The energy source can be protons, X-rays, or something else. After surgery, radiation therapy is often employed to treat gliomas. The radiation kills the leftover glioma cells after surgery. Radiation and chemotherapy are usually combined.

Targeted Therapy: Targeted therapy treatments focus on specific substances in cancer cells. Targeted therapy treatments can kill cancer cells by inhibiting these substances.


Cost Start From USD 7500 - USD 12000Explore Options

  • Neurological Exam: A detailed neurological and physical exam to assess for symptoms like weakness, changes in vision, or coordination difficulty.
  • MRI is the most common method of imaging used for glioma detection. It can take detailed brain pictures and determine the size, position, and type of tumours.
  • Computed tomography (CT) scans are occasionally substituted for MRIs but are not as detailed.
  • Biopsy: A tumour tissue biopsy is taken for laboratory analysis to determine the type and grade of the gliomas.
  • PET scans (positron emission tomography) are sometimes combined to assess tumour metabolism and assist with therapy planning.

MediRehab (chain of Rehab centres - Part of MediGence) provides comprehensive rehabilitation services rehabilitation services to support patients through Teleconsulations and online therapy sessions.

  • Physical Therapy: To enhance mobility, strength, and coordination, particularly if the tumour or surgery has impacted motor function.
  • Occupational Therapy: Assists patients in recovering the skills to do daily tasks and enhance fine movements, including dressing, eating, and writing.
  • Speech Therapy assists in the recovery of speech and swallowing function if the glioma or its treatment has impaired these functions.
  • Cognitive Rehabilitation helps patients cope with memory, attention, and other mental processes affected by the tumour or treatment.
  • Depending on the situation, your healthcare professional may prescribe medicine to help control your symptoms and support the treatment plan.

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Hospitals for Glioma in Turkey

Florence Nightingale Hospital: Top Doctors, and Reviews
Florence Nightingale Hospital

Istanbul, Turkey

The first green hospital in Turkey, Istanbul Florence Nightingale Hospital, was inaugurated in 2013. Group The Florence Nightingale hospitals are the first Turkish hospitals to be granted Joint Commission International (JCI) accreditation, and they continue to be associated and work with esteemed healthcare organizations.

The Florence Nightingale Group treats 250,000 outpatients and 70,000 inpatients annually, demonstrating its excellence. The hospitals have a capacity of 804 inpatient beds, 141 ICU beds, and 40 operating rooms, and perform 20,000+ procedures annually, of which 1,000 are cardiac operations for children and 2,000 are for adults. For conducting difficult orthopedic, general surgery, minimally invasive, and other heart treatments, the facility stands out. All operating rooms can be interconnected by audio-visual to a 300-person conference room and global hubs, enabling interactive medical teaching and scientific activity.

Interpreter and translator services for languages such as Turkish, Azerbaijani, Bulgarian, Arabic, English, Persian, Serbian, Russian, Albanian, Macedonian, German, Bosnian, and Romanian are available.

The hospital has specialized departments such as Cardiology and Cardiac Surgery, IVF and Infertility, Nephrology, Oncology and Oncosurgery, Spine Surgery, Neurology and Neurosurgery, Orthopedics, Gynecology, and Obesity or Bariatric Surgery. With an extensively qualified and experienced team of advisors and interpreters, Florence Nightingale Istanbul is committed to providing one-stop service from beginning to end, 24 hours a day, 7 days a week.

Medipol Bahçelievler Hospital: Top Doctors, and Reviews
Medipol Bahçelievler Hospital

Istanbul, Turkey

Medipol Bahcelievler Hospital is a medical institution providing a full range of medical and individualized approaches to its patients. Medipol has the ambition to bring high quality and maximum security to people in need by employing state-of-the-art technologies in medicine. They ensure that the health of the patients is improved by fashioning unique physician specialty treatment programs.

Medipol Bahcelievler Hospital provides an exceptional position in the healthcare industry with a policy of clear communication, professionalism, and reliability to patient expectations. Medipol Bahçelievler Hospital is situated in the European Side of Istanbul, dedicated to 24-hour health care for you and your loved ones, equipped with a fully functional operation theatre and ICUs with state-of-the-art equipment, laboratory, emergency, and advanced treatment rooms

Acibadem Altunizade Hospital: Top Doctors, and Reviews
Acibadem Altunizade Hospital

Istanbul, Turkey

Acibadem Altunizade Hospital located in Istanbul, Turkey is accredited by JCI. Also listed below are some of the most prominent infrastructural details:

  • The indoor area of Acibadem Hastanesi - Altunizade, Istanbul, Turkey is one of the largest at 98,000 square meters.
  • There are 550 beds and as many parking spots.
  • 75 of the beds are in the intensive care unit.
  • A hybrid operating room which has 3 diagnostic units at one location which is an amazing concept as at one time surgeries can be performed in 3 operating theatres.
  • International patients are serviced well through a particular center for them where services related to therapy and diagnostics are done.
  • Healthcare delivery in this part of the hospital can be availed in 16 different languages.
  • Robotic Surgery and Cell Therapy Unit are representative of the high standards of technology present in the hospital.

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Why Choose Turkey for Glioma Treatment?

Turkey is an ideal location to treat gliomas as it provides the latest immunotherapies under initiatives such as the TTCI and advanced surgical techniques such as awake craniotomy for precise tumour removal. Turkey provides glioma patients with effective and personalised treatment because of its highly trained physicians, state-of-the-art facilities, and affordable healthcare.

Frequently Asked Questions

The following are the main differences between high-grade and low-grade gliomas:

  • Low-gradegliomas, typically grade I or II, are less aggressive, grow more slowly, and have a better prognosis.
  • High-grade gliomas, like glioblastoma, are often graded as grade III or IV because they are more malignant and develop rapidly.

Surgery is often recommended in Turkey for treating gliomas, particularly if the tumours are removed safely. However, other therapies such as radiotherapy, chemotherapy, or immunotherapy may also be considered, often in addition to surgery, to achieve the best results, depending on factors such as tumour size, location, and the patient's health. Treatment for each patient is tailored to suit their individual needs.

Gliomas may recur after treatment. Recurrence depends on several factors, such as the location, grade, and type of the glioma. Due to their aggressive nature, glioblastoma and other high-grade gliomas are more likely to recur. Despite successful initial treatment, glioma cells might remain in the brain, which may result in the tumour's recurrence.

The tumour grade, location, type, and overall patient health influence the glioma survival rate in Turkey. More aggressive tumours, like glioblastoma, may have a lower survival rate, though current advances in immunotherapy, radiation, and surgery have promising results. The treatment plan for each patient is personalised to ensure the best possible prognosis, and early detection and individualised treatment significantly enhance survival rates.

The following lifestyle modifications can help in the management of glioma symptoms:

  • Regular, moderate exercise can enhance strength, decrease fatigue, and increase general well-being.
  • A well-balanced diet containing plenty of fruits, vegetables, and whole grains can improve overall well-being, enhance energy levels, and boost the immune system.
  • The relaxation skills of meditation, deep breathing, or yoga can be used to minimise stress and anxiety.
  • Resting properly and getting quality sleep assists in managing tiredness and facilitating the body's healing process.
  • Prescribed pain medications and complementary therapies like massage or acupuncture can help control discomfort.
  • Participation in cognitive therapy or support groups can treat cognitive problems and offer emotional support throughout treatment.

Yes, you can get a second opinion on Glioma treatment in Turkey through MediGence. With MediGence, you can connect with highly experienced professionals from top Turkish hospitals who can provide additional information regarding your diagnosis and treatment options. The platform facilitates easy access to professional help so you can make informed healthcare choices and receive the best care possible.

To find a certified cancer specialist, search MediGence’s website, which offers a list of top-class and internationally trained oncologists from Turkey's best hospitals. Through MediGence, you can search the profiles of specialists, check their credentials, reviews, and experience, and book online consultations. To get the best care for your condition, the website also assists you in finding the best hospitals and provides personalised assistance for your health requirements.