Dr. Meltem Topalgokceli Selam

Dr. Meltem Topalgokceli Selam

Cancer Specialist - Medical Oncologist

  Liv Hospital Ulus, Istanbul, Turkey

  12 Years of experience

   160 USD for Video Consultation


Qualification and Experience

Dr Meltem Topalgokceli is a distinguished medical oncologist. She has many years of experience under her belt and is currently serving at the Liv Hospital Ulus, Istanbul, Turkey. She specialises in Medical Oncology, Gastrointestinal System Cancers and Ovarian Cancers. She obtained her medical education from the Istanbul University Istanbul Faculty of Medicine. She has previously also worked at the Ministry of Health Istanbul Training and Research Hospital, Internal Medicine Department. 

Contribution to Medical Science

Dr Meltem Topalgokceli has been a part of many medical articles written in renowned journals. Her articles have been published in 4 different international journals. She is also a member of many medical associations such as the Turkish Medical Oncology Association, Istanbul Breast Research Group and the Üsküdar American High School Alumni Association.

Past Experience

  • LIV, Ulus, Department of Medical Oncology
  • Ministry of Health Okmeydani Education and Research Hospital, Department of Medical Oncology
  • Istanbul Faculty of Medicine Oncology Institute, Department of Medical Oncology
  • Ministry of Health Okmeydani Education and Research Hospital, Department of Internal Medicine
  • Ministry of Health Istanbul Education and Research Hospital, Department of Internal Medicine


  • Istanbul University Istanbul Faculty of Medicine
  • Uskudar American High School for Girls
  • Turkish Medical Oncology Association
  • Istanbul Breast Research Group
  • Clinicopathological prognostic factors and evaluation of chemotherapy regimens containing platinum.
  • Effect of maximum-tolerated doses and low-dose metronomic chemotherapy on serum vascular endothelial growth factor and thrombospondin-1 levels in patients with advanced nonsmall cell lung cancer.
  • Psoriasis agrevatation due to Lapatinib.
  • A Fulminant Case of Leptomeningeal Carcinomatosis secondary to Esophageal Adenocarcinoma.

Chemotherapy is a category of standardized drug administration of various types for the treatment of cancer. With a curative intent, some combinations of drugs are administered to a patient to prolong their life and also to bring about a reduction in the symptoms shown by the patient. Chemotherapy treatment is considered to be one of the major categories of medical oncology. Many people around the world are prescribed to undergo chemotherapy treatment instead of undergoing a surgical procedure. But many are frightened with the side effects of this treatment as it is believed to reduce the quality of life of the patients.

What is chemotherapy?

Chemotherapy is a procedure where non-specific intracellular poisons are used, which are specifically related to preventing the process of mitosis or the natural cell division of the cancerous cells. This technique rather excludes those agents that are responsible for selective extracellular growth signal blockade (signal transduction blockers). If spoken about these agents used in chemotherapy, it has been found that most of them are cytotoxic in nature due to their property of interfering with natural mitosis. However, the cells of cancer can differ widely in terms of showing susceptibility to these administered agents.

Chemotherapy can be defined as a way of mass destruction of stress cells, which would eventually lead to the death of the cells when apoptosis is initiated. The commonly known side effects of chemotherapy can be traced back to the process of damaging normal non-cancerous cells, which are in the process of rapid division. They are sensitive to anti-mitotic drugs that are being administered to the patient and such cells may include the cells of the hair follicles, digestive tract lining, and bone marrow. But nowadays treatment options have undergone a lot of modification by which these side effects can be well countered.

Types of Chemotherapy Drugs

Various options of drugs are available to treat different types of cancer including the following:

Alkylating agents: These kinds of agents prove to be extremely beneficial during the cell’s resting phase. The various kinds of alkylating agents that are employed in chemotherapy treatment include the following:

  • Mustard gas derivatives: Cyclophosphamide, mechlorethamine, chlorambucil, ifosfamide, melphalan
  • Ethylenimines: Thiotepa and hexamethylmelamine
  • Alkylsulfonates: Busulfan
  • Metal salts: Oxaliplatin, cisplatin, and carboplatin
  • Nitrosoureas: Streptozocin, lomustine, carmustine

Nitrosoureas are unique from the rest for choices in chemotherapy treatment due to their ability to cross the blood-brain barrier and treating tumors of the brain.

Plant alkaloids: Plant alkaloids employed for chemotherapy treatment are derived from plants.  These include vinca alkaloids, taxanes, podophyllotoxins, and camptothecan analogs. The plant alkaloids are cell cycle specific agents, which enables them to attack the dividing cells in various stages of their division cycle.

Antimetabolites: This kind of chemotherapy treatment involves substances that are similar in composition to the normal substances present in the cell. When these substances get incorporated in the process of cellular metabolism, then the cell is no longer able to divide. They are also cell cycle specific and can be classified further according to the substance in the cell with which they interfere.

Topoisomerase inhibitors: When the topoisomerase enzymes in the body ( topoisomerase I and II) are inhibited as a result of chemotherapy drugs, then those drugs are referred to as topoisomerase inhibitors. During the chemotherapy, the topoisomerase enzymes are responsible for controlling structural manipulation of the DNA which is necessary for the purpose of replication.

Miscellaneous antineoplastics: Different types of drugs make each chemotherapy treatment process unique. Enzymes, retinoids, adrenocortical steroid inhibitor, ribonucleotide reductase inhibitor or antimicrotubule agents can be used as chemotherapy drugs.

Frequently Asked Questions
How many years of experience does Dr Meltem Topalgokceli have being a medical oncologist in Turkey?

Dr Meltem has 12 years of experience in her field as a cancer specialist.

What are the primary treatments and surgeries does Dr Meltem Topalgokceli as a medical oncologist?

She specialises in Medical Oncology, Gastrointestinal System Cancers and Ovarian Cancers.

Does Dr Meltem Topalgokceli provide Online Consultation?

Yes, Dr Meltem provides online consultation through MediGence.

How much does it cost to consult online with Dr Meltem Topalgokceli?

It costs 160 USD for online consultation with Dr Meltem.

What associations is Dr Meltem Topalgokceli part of?

She is a member of many medical associations such as the Turkish Medical Oncology Association, Istanbul Breast Research Group and the Uskudar American High School Alumni Association.

When do you need to see a medical oncologist such as Dr Meltem Topalgokceli?

Dr Meltem is a cancer specialist. She has expertise in treating diagnosing and giving adequate treatment for various cancers in the body. She Specialises in ovarian and cancers related to the digestive system.

How to connect with Dr Meltem Topalgokceli for Online Consultation through MediGence?

She can be easily consulted by registering your profile with MediGence and writing down your enquiry. A meeting with the surgeon will be scheduled. Following which the consultation can be done.

What area of specialization does Dr. Meltem Topalgokceli Selam have?
Dr. Meltem Topalgokceli Selam is specialized in Turkey and of the most sought after doctors in Cancer Specialist.
Does Dr. Meltem Topalgokceli Selam offer Telemedicine Consultation through Medigence?
Yes. Dr. Meltem Topalgokceli Selam offers telemedicine via MediGence. Top Cancer Specialist in Turkey like Dr. Meltem Topalgokceli Selam are offering second opinions and video consultations at the click of a button. One can clear all their queries before opting to travel abroad for treatment with the power of Online Doctor Consultation.
What is the process of scheduling a Telemedicine call with Dr. Meltem Topalgokceli Selam?
To avail a Telemedicine call with Dr. Meltem Topalgokceli Selam, the interested candidate should:
  • Search Dr. Meltem Topalgokceli Selam on the MediGence website search bar
  • Click the video icon against his profile
  • Select an appropriate date
  • Register on the website
  • Upload necessary documents
  • Make the payment via secured payment gateway of Paypal
  • Join the video call by clicking the link received over email on decided date and time
How many years of experience does Dr. Meltem Topalgokceli Selam have?
Dr. Meltem Topalgokceli Selam is one of the most sought after specialists in Turkey and has over 12 Years years of experience.
What is the consulting fee of Dr. Meltem Topalgokceli Selam?
The consultation fees of Cancer Specialist in Turkey like Dr. Meltem Topalgokceli Selam starts from USD 160.
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