Castleman disease is a group of rare disorders characterized by enlarged lymph nodes and a wide range of symptoms. The most common form of the disorder involves a single enlarged lymph node, typically found in the chest or neck, but it can occur in other areas of the body as well. This form is known as Unicentric Castleman Disease (UCD).
Multicentric Castleman Disease (MCD), on the other hand, involves multiple regions of enlarged lymph nodes, along with inflammatory symptoms and problems with organ function.

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