Glomerulonephritis is a group of kidney conditions in which the glomeruli, the kidneys' tiny blood-filtering units, become inflamed and damaged. This can interfere with the kidneys' ability to remove waste and excess fluid while retaining essential proteins and blood cells. Depending on the cause and severity, glomerulonephritis may cause blood or protein in the urine, swelling, high blood pressure and reduced kidney function. Some forms are temporary, while chronic or rapidly progressive disease can lead to chronic kidney disease or kidney failure.
Timely evaluation and treatment can help identify the underlying cause, control inflammation, and reduce further kidney damage. Early management of high blood pressure, protein loss and fluid retention can help protect kidney function. In immune-mediated forms, appropriate treatment may reduce ongoing inflammation, while infection-related forms may require treatment of the underlying infection. Rapidly progressive glomerulonephritis requires urgent specialist assessment because kidney function can deteriorate quickly.
Causes
Risk Factors
Targeted Treatment : Depending on the underlying disease, treatment may include antimetabolites, alkylating agents or targeted biological therapies. Treatment should be based on the specific diagnosis, often supported by kidney biopsy and other investigations.
Kidney Transplantation : Patients with advanced kidney failure may need kidney replacement therapy, including hemodialysis or peritoneal dialysis. Kidney transplantation may be considered for eligible patients with irreversible kidney failure.
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Dialysis: Temporary or long-term dialysis may be required when kidney function becomes severely impaired or complications cannot be controlled with medicines.
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Istanbul, Turkey
Acibadem Altunizade Hospital located in Istanbul, Turkey is accredited by JCI. Also listed below are some of the most prominent infrastructural details:

Istanbul, Turkey
Acibadem International Hospital located in Istanbul, Turkey is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
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Dr. Akash Khandelwal is a distinguished Hematologist, Hemato-oncologist, and Bone Marrow Transplant (BMT) Physician with extensive training from the prestigious AIIMS New Delhi. His expertise encompasses a wide range of specialized techniques in bone marrow transplantation, including autologous and allogeneic transplants such as matched sibling donors, matched unrelated donors (MUD), and haploidentical donor transplants. Dr. Khandelwal has personally supervised and conducted over 100 bone marrow transplants. View More
Last Reviewed - January 2026