The oncology center at Sri Ramachandra Medical Centre adheres strictly to evidence-based international and national cancer treatment guidelines. They offer comprehensive treatment options for kidney cancer, including Onco Surgery, Radiotherapy, Chemotherapy, and Supportive Care. Biological therapy (targeted agents and monoclonal antibodies) is also available at the center. The SRMC cancer center has cutting-edge technology for Advanced Laparoscopy and minimal-access surgeries. Nephrectomy and ablation are procedures used to treat kidney cancer.

Elekta U.K.'s VERSA HD digital Linac, equipped with the most recent 160-leaf AGILITY MLC and USG-based Image guidance unit CLARITY, offers the fastest high-precision radiotherapy available today. Modern radiotherapy treatment techniques such as 3D CRT, IMRT, IGRT, and VMAT (Rapid Arc), as well as stereotactic and triple F treatment, are possible with the VERSA HD. The department also uses the HDR Microselectron Machine to provide HDR Brachytherapy treatment for a variety of cancers. The hospital also has an M/s Siemens of Germany Biograph Horizon model PET CT scanner. Some of the skilled doctors associated with Sri Ramachandra Medical Centre include Dr. M. Manickavasagam, Dr. S. Lakshminarasimhan, Dr. K. Satish Srinivas, Dr. Christopher John, and Dr. J.S. Lakhmi.