Dr. Onder Tonyali

Dr. Onder Tonyali

Cancer Specialist - Medical Oncologist

  , Konya, Turkey

  10 Years of experience


Qualification and Experience

Dr. Onder Tonyali is an oncologist in Konya. He has overall experience of more than 15 years. He is a well-known oncologist in the area. He is currently providing his services at Medicana Konya Hospital, Konya in Medical Oncology Department as Associate Professor of Medicine. During his long career, he has associated with various organizations of repute such as Kartal Education and Research Hospital, Agri State Hospital, Private Istanbul Oncology Hospital, Hatay Antakya State Hospital, Gazi University Faculty of Medicine, and Mustafa Kemal University School of Medicine. Dr. Tonyali completed his Graduation from Istanbul University Cerrahpasa School of Medicine in the year 2003. Later, in 2011, he completed residency program in Medical oncology from Gazi University School of Medicine.

Contribution to Medical Science

Dr. Onder Tonyali is extensively experienced oncologist in Konya. He is known for developing various treatment strategies according to patient’s condition. He manages and treats various types of cancer with high success rate. His area of service includes Breast Cancer Treatment, Lung Cancer Treatment, Genitourinary System Cancers, Colorectal Cancer Treatment, Treatment of esophageal and gastric cancers, and Brain Tumors. He is also an expert in managing skin cancers. Apart from the cancer therapies, Dr. Tonyali is also an expert in accurate diagnosis of cancer through various diagnostic measures. He has hands-on experience in diagnosing cancers through PET screening, Bone scan and CT Scan. Research articles of Dr. Tonyali have been published in various national and international journals. He is also the member of medical associations. Using new chemotherapeutic agents, Dr. Onder Tonyali successfully increases the life of patients along with enhanced quality of life.

Past Experience

  • Agri State Hospital (2008)
  • Gazi University Faculty of Medicine (2008-2011)
  • Hatay Antakya State Hospital (2012-2014)
  • Mustafa Kemal University School of Medicine (2014-2016)
  • Kartal Education and Research Hospital (2016-2017)
  • Private Istanbul Oncology Hospital (2017-2019)
  • Medicana Konya Hospital, Konya, Department of Medical Oncology, M.D. Associate Professor of Medicine (2019-present)


  • Graduate Education Istanbul University Cerrahpasa School of Medicine (2003)
  • Postgraduate Education (Residency) Gazi University School of Medicine, Department of
  • Medical Oncology Residency Program (2011)
  • Various research articles and papers submitted in international and national journals.

Chemotherapy is a category of standardized drug administration of various types for the treatment of cancer. With a curative intent, some combinations of drugs are administered to a patient to prolong their life and also to bring about a reduction in the symptoms shown by the patient. Chemotherapy treatment is considered to be one of the major categories of medical oncology. Many people around the world are prescribed to undergo chemotherapy treatment instead of undergoing a surgical procedure. But many are frightened with the side effects of this treatment as it is believed to reduce the quality of life of the patients.

What is chemotherapy?

Chemotherapy is a procedure where non-specific intracellular poisons are used, which are specifically related to preventing the process of mitosis or the natural cell division of the cancerous cells. This technique rather excludes those agents that are responsible for selective extracellular growth signal blockade (signal transduction blockers). If spoken about these agents used in chemotherapy, it has been found that most of them are cytotoxic in nature due to their property of interfering with natural mitosis. However, the cells of cancer can differ widely in terms of showing susceptibility to these administered agents.

Chemotherapy can be defined as a way of mass destruction of stress cells, which would eventually lead to the death of the cells when apoptosis is initiated. The commonly known side effects of chemotherapy can be traced back to the process of damaging normal non-cancerous cells, which are in the process of rapid division. They are sensitive to anti-mitotic drugs that are being administered to the patient and such cells may include the cells of the hair follicles, digestive tract lining, and bone marrow. But nowadays treatment options have undergone a lot of modification by which these side effects can be well countered.

Types of Chemotherapy Drugs

Various options of drugs are available to treat different types of cancer including the following:

Alkylating agents: These kinds of agents prove to be extremely beneficial during the cell’s resting phase. The various kinds of alkylating agents that are employed in chemotherapy treatment include the following:

  • Mustard gas derivatives: Cyclophosphamide, mechlorethamine, chlorambucil, ifosfamide, melphalan
  • Ethylenimines: Thiotepa and hexamethylmelamine
  • Alkylsulfonates: Busulfan
  • Metal salts: Oxaliplatin, cisplatin, and carboplatin
  • Nitrosoureas: Streptozocin, lomustine, carmustine

Nitrosoureas are unique from the rest for choices in chemotherapy treatment due to their ability to cross the blood-brain barrier and treating tumors of the brain.

Plant alkaloids: Plant alkaloids employed for chemotherapy treatment are derived from plants.  These include vinca alkaloids, taxanes, podophyllotoxins, and camptothecan analogs. The plant alkaloids are cell cycle specific agents, which enables them to attack the dividing cells in various stages of their division cycle.

Antimetabolites: This kind of chemotherapy treatment involves substances that are similar in composition to the normal substances present in the cell. When these substances get incorporated in the process of cellular metabolism, then the cell is no longer able to divide. They are also cell cycle specific and can be classified further according to the substance in the cell with which they interfere.

Topoisomerase inhibitors: When the topoisomerase enzymes in the body ( topoisomerase I and II) are inhibited as a result of chemotherapy drugs, then those drugs are referred to as topoisomerase inhibitors. During the chemotherapy, the topoisomerase enzymes are responsible for controlling structural manipulation of the DNA which is necessary for the purpose of replication.

Miscellaneous antineoplastics: Different types of drugs make each chemotherapy treatment process unique. Enzymes, retinoids, adrenocortical steroid inhibitor, ribonucleotide reductase inhibitor or antimicrotubule agents can be used as chemotherapy drugs.

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Frequently Asked Questions
What area of specialization does Dr. Onder Tonyali have?
Dr. Onder Tonyali is specialized in Turkey and of the most sought after doctors in Cancer Specialist.
Does Dr. Onder Tonyali offer Telemedicine Consultation through Medigence?
No, this doctor dose not offer telemedicine via MediGence
How many years of experience does Dr. Onder Tonyali have?
Dr. Onder Tonyali is one of the most sought after specialists in Turkey and has over 10 Years years of experience.
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