Hypertrophic Cardiomyopathy Treatment in Singapore
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What is Hypertrophic Cardiomyopathy?
Hypertrophic Cardiomyopathy is a heart muscle disease characterised by abnormal thickening of the ventricular walls that cannot be explained solely by conditions such as high blood pressure or abnormal heart valves. In some patients, the thickened muscle obstructs blood flow from the heart, while in others, the disease is non-obstructive. HCM can be inherited and may occur at different ages.
What is the Importance of Timely Treatment?
Timely treatment of Hypertrophic Cardiomyopathy helps control symptoms, assess whether thickened heart muscle is obstructing blood flow, reduce the risk of complications such as heart failure and arrhythmias, and identify patients who may benefit from an implantable cardioverter-defibrillator (ICD). Regular follow-up also supports long-term heart health by guiding medicines, activity, lifestyle, and family screening.
What are the Common Symptoms of Hypertrophic Cardiomyopathy?
- Shortness of Breath: Breathlessness may occur during physical activity or, in more advanced cases, at rest.
- Chest Pain: Some patients experience chest discomfort, particularly during exertion.
- Palpitations: A sensation of a racing, pounding, or irregular heartbeat may occur because of abnormal heart rhythms.
- Dizziness: Reduced cardiac output or abnormal rhythms may cause lightheadedness, particularly during activity.
- Fainting: Episodes of unexplained fainting may occur and require medical evaluation, especially in people with known HCM.
- Fatigue: Reduced ability of the heart to fill or pump efficiently can lead to tiredness and reduced exercise tolerance.
Causes and Risk Factors of Hypertrophic Cardiomyopathy
Causes
- Inherited Genetic Changes: Most familial HCM is linked to genetic variants that affect proteins involved in heart muscle contraction.
- Spontaneous Genetic Changes: Some patients develop HCM without a known family history.
- Unexplained Causes: In some individuals, no specific genetic or other cause is identified.
- Associated Conditions: Some heart-muscle disorders can produce thickening that resembles HCM and require careful evaluation to distinguish them from true HCM.
Risk Factors
- Family History: Having a first-degree relative with HCM or unexplained sudden cardiac death can increase risk.
- Genetic Predisposition: Inherited disease-causing variants can increase susceptibility.
- Age: HCM can become apparent during childhood, adolescence, adulthood, or later life.
- Previous Abnormal Cardiac Findings: Unexplained heart-muscle thickening or abnormal ECG findings may prompt further assessment.
- Family History of Sudden Cardiac Death: This may be an important factor in individual risk assessment.
Latest Research and Technologies in the Treatment of Hypertrophic Cardiomyopathy in Singapore
- Cardiac MRI now gives detailed measurements of heart-muscle thickness and scar, advanced echocardiography shows exactly where and when blood flow is blocked, and genetic testing helps identify at-risk family members. Cardiac myosin inhibitors, such as mavacamten, are a newer targeted medicine that can reduce obstruction and improve symptoms in selected adults with symptomatic obstructive HCM. [Confirm which myosin inhibitors are currently available in Singapore.] Better risk assessment tools help doctors decide who benefits from an ICD, and specialised centres offer septal reduction procedures, including surgical myectomy and selected catheter-based approaches.
Treatment options for Hypertrophic Cardiomyopathy
Septal Myectomy: This open-heart surgical procedure (Morrow procedure) remains the gold-standard intervention to physically excise a portion of the hypertrophied septum and relieve left ventricular outflow tract (LVOT) obstruction.
Alcohol Septal Ablation: A minimally invasive, catheter-based alternative to surgery where pure alcohol is injected into a septal branch artery to induce a localised controlled infarction, thinning the muscle to reduce obstruction.
Implantable Cardioverter-Defibrillator (ICD) : Because HCM is a leading cause of sudden cardiac death in young people and athletes due to ventricular arrhythmias, primary or secondary prevention with an ICD is an essential treatment pillar.
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Heart Transplantation : For the small percentage of HCM patients who progress to end-stage, non-obstructive "burnt-out" heart failure, an orthotopic heart transplant is the final definitive option
- Clinical assessment:
- Medical and Family History: Assessment of symptoms, exercise tolerance, previous fainting, family history of HCM, and sudden cardiac death.
- Physical Examination: Evaluation for heart murmurs, abnormal heart sounds, blood pressure changes, and signs of heart failure.
- Electrocardiogram (ECG): May identify abnormal electrical patterns associated with HCM.
- Holter or Ambulatory ECG Monitoring: Detects intermittent arrhythmias that may not appear on a standard ECG.
- Exercise Testing: May assess exercise capacity, blood pressure response, symptoms, and exercise-related obstruction.
- Genetic Testing: May be offered to selected patients to identify disease-causing variants and support family screening.
- Imaging Tests:
- Echocardiography: The main imaging test used to assess heart-muscle thickness, heart function, valve movement, and obstruction.
- Cardiac MRI: Provides detailed images of heart structure and can identify myocardial scar and other tissue characteristics.
- Stress Echocardiography: May reveal obstruction or abnormalities that become apparent during exercise.
- Chest X-ray: May help evaluate heart size and associated lung findings when clinically indicated.
- Cardiac CT: Consider in selected patients when additional anatomical information is needed.
MediRehab (a chain of Rehab centres, part of MediGence) provides comprehensive tele-rehabilitation services designed to support Hypertrophic Cardiomyopathy patients in Singapore. These services include:
- Individualised Exercise: Appropriate physical activity can be encouraged according to symptoms, disease severity, and specialist advice.
- Cardiac Rehabilitation: Selected patients may benefit from structured, supervised rehabilitation.
- Physical Conditioning: Gradual activity can help maintain functional capacity while avoiding inappropriate exertion.
- Weight Management: Maintaining a healthy weight can reduce additional cardiovascular strain.
- Long-Term Follow-Up: Regular cardiology assessments help monitor symptoms, heart function, rhythm, and response to treatment.
- Select medicines based on symptoms, obstruction, heart rhythm, and overall heart function. Beta-blockers and certain calcium-channel blockers may help reduce symptoms and improve ventricular filling. Selected patients with obstructive HCM may receive cardiac myosin inhibitors, while antiarrhythmic or anticoagulant medicines may be prescribed when clinically indicated. Treatment should be supervised by a cardiologist experienced in HCM.
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Hospitals for Hypertrophic Cardiomyopathy in Singapore
Parkway East Hospital
Singapore, Singapore
Parkway East Hospital located in Joo Chiat Pl, Singapore is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- Total capacity for 143 beds
- Hospital rooms are available- Single room, 2-bedded room (8), 4-bedded room (2), Deluxe room, and Orchid/Hibiscus Suite
- All rooms are equipped with all ensuite facilities like Free wifi, mini fridge, sofa couch, telephone, in-room safe, TV, etc.
- Maternity wards- Accredited as a baby-friendly hospital under the World Health Organisations Baby-Friendly Hospital Initiative (BFHI)
- 1 Neonatal Intensive Care Unit (NICU) with 14 cots
- Intensive Care Unit
- 1 Operation Theatre with 5 Operating rooms
- 1 Nursery with 30 cots
- 1 Parentcraft room
- 24-hour walk-in-clinic (for emergency)
- 24-hour Pharmacy
Mount Elizabeth Hospital
Singapore, Singapore
Mount Elizabeth Hospital located in Singapore, Singapore is accredited by JCI. Also listed below are some of the most prominent infrastructural details:
- 345 bedded Hospital
- Maternity wards
- The Mount Elizabeth Patient Assistance Centre (MPAC)
- 1 major operating unit with 12 operating rooms and 1 operating theatre dedicated to in vitro fertilisation (IVF)
- Intensive Care Unit
- High Dependency Unit (HDU)
- Neonatal Intensive Care Unit (NICU)
- Accident & Emergency Department
- Rooms are categorized as Single rooms, 2-bedded rooms, 4-bedded rooms, Executive deluxe suite, Daffodil/Magnolia suite, VIP Room, and Royal Suite
- All patient rooms are equipped with electric safe, LCD, sofa cum bed, wardrobe, radio channels, and much more
- Parking lot
Farrer Park Hospital
Singapore, Singapore
Apart from in-detail treatment procedures available, Farrer Park Hospital located in Connexion, Singapore has a wide variety of facilities available for International Patients. Some of the facilities which are provided by them are Accommodation, Airport Transfer, Choice of Meals, Interpreter, SIM, TV inside room. Also listed below are some of the most prominent infrastructural details:
- A medical centre is linked to the Farrer Park Hospital Complex, Connexion, Singapore
- The focus of the hospital is to bring together two essential elements: those of healthcare combined with hospitality.
- There is a building with 20 different stories which comprises Owen Link, hotel and spa.
- Personal attention and patient care focus is maintained with a system in place of listening, analysing, evaluating and then implementing a treatment plan.
- 121 bed capacity
- Technology and innovations help provide the best of medical and surgical treatment options.
- Professionally implemented international patient care systems
- Suites: Cardiovascular, day surgery, endoscopy, major surgery, nuclear medicine, radiation oncology, and inpatient suite
- Diagnostic imaging and intensive care unit
- 24 hour emergency clinic and pharmacy
- Facilities such as dialysis, nutrition services, rehab centre, and teaching clinic
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Why Choose Singapore for Hypertrophic Cardiomyopathy Treatment?
- Experienced Cardiac Specialists: Singapore has cardiologists, electrophysiologists, cardiac surgeons, and specialists experienced in managing complex heart-muscle disorders.
- Advanced Cardiac Imaging: Major centres may offer advanced echocardiography, cardiac MRI, CT, and ambulatory rhythm monitoring.
- Specialised HCM Management: Appropriate patients may have access to medicines, cardiac myosin inhibitors, septal myectomy, alcohol septal ablation, and ICD implantation.
- Advanced Electrophysiology Services: Specialist centres can evaluate and manage arrhythmias and assess the need for ICDs.
- Multidisciplinary Care: Cardiology, electrophysiology, cardiac surgery, genetics, imaging, rehabilitation, and other specialists can collaborate for complex cases.
- Genetic Evaluation: Selected patients and families can undergo genetic counselling and testing where appropriate.
- Personalised Treatment: Management is tailored according to symptoms, obstruction, heart function, arrhythmia risk, and genetic or family history.
- International Patient Support: Many major Singapore hospitals offer assistance with appointments, treatment coordination, accommodation, and follow-up for international patients.
Frequently Asked Questions
Reviewer
Dr. Nityanand Tripathi
Interventional Cardiologist
29 Years of Experience
With a rich experience of more than 29 years, Dr. Nityanand has gained a vast spectrum of skills and expertise in performing all types of complex cardiac procedures. He is an expert in clinical & interventional cardiology and electrophysiology. He studied his medicine (MBBS) and MD from the Institute of Medical Sciences of Banaras Hindu University, Varanasi, and later completed his DM in Cardiology from the prestigious King George Medical University, Lucknow. View More
Last Reviewed - January 2026