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What is Epithelial Ovarian Cancer?

The most prevalent kind of ovarian cancer is epithelial. This cancer starts in the epithelial tissue, a thin membrane covering the outside of the ovary.

Cancer may also develop in the lining of a fallopian tube. It could also begin in the peritoneum, the tissue surrounding your abdominal organs.

Medical professionals classify fallopian tube malignancies and primary peritoneal cancers as epithelial ovarian cancers.

What is the Importance of Timely Treatment?

Timely treatment of epithelial ovarian cancer is essential for increasing survival rates and quality of life. Early detection and intervention, such as surgery and chemotherapy, can dramatically improve treatment outcomes and remission rates.

Cancer is frequently identified in its later stages, when it has spread to other places, making treatment more challenging. Delaying therapy may allow the cancer to develop, potentially leading to problems such as organ damage, intestinal obstruction, and ascites (fluid accumulation).

Early and immediate therapy allows for better disease control, symptom management, and prevention of cancer spread, resulting in a better prognosis.

What are the Common Symptoms of Epithelial Ovarian Cancer?

Epithelial ovarian cancer rarely produces symptoms in its early stages. Symptoms worsen as the condition advances. As it spreads into your peritoneum (the tissue surrounding your abdominal organs), fluid accumulates in your abdomen (ascites).

  • Symptoms may include abdominal ache
  • Difficulty eating or becoming full quickly
  • Nausea and vomiting
  • Bloating
  • Pelvic discomfort
  • Less common symptoms include urge incontinence and hyperactive bladder
  • Vaginal bleeding

Types of Epithelial Ovarian Cancer

Various types of epithelial ovarian cancer include :

  • Serous ovarian cancer
  • The most frequent type of ovarian cancer is high-grade serous carcinoma (grades 3 or 4). Its name includes the word "serous" because this type of cancer grows in the serous membrane of the epithelial layer of cells that lines the patient's abdomen and pelvis.
  • Low-grade serous carcinoma, the fourth most prevalent type of ovarian cancer, has cancer cells that proliferate at a slower rate than high-grade serous cancer.
  • Endometrioid ovarian carcinoma
  • This kind of cancer, which accounts for approximately 20% of all epithelial ovarian cancer cases, is frequently identified in earlier stages than serous ovarian carcinoma. It is commonly found in people who have a history of endometriosis.
  • Clear-cell carcinoma
  • Also known as "clear cell adenocarcinoma," this is a rare kind of epithelial ovarian cancer in which the cells appear clear under a microscope. It is also suspected to be associated with endometriosis.
  • Mucinous carcinoma
  • One of the most uncommon types of ovarian cancer, this subtype is distinguished by tumors with aberrant mucus-secreting cells. It is the most common subtype of epithelial ovarian cancer found in women under 40.

Causes, Risk Factors and Complications of Epithelial Ovarian Cancer

Causes

According to recent research, many ovarian malignancies begin in cells at the end of the fallopian tubes. Then they spread to the ovaries.

Risk Factors

Certain factors may raise your risk of ovarian cancer, including:

  • Family history of ovarian, breast, or colorectal cancer.
  • Inheriting a mutation in the BRCA gene.
  • Inheriting a gene associated with family cancer disorders such as Lynch syndrome.
  • Hormone treatment for menopausal symptoms.
  • Having a baby after age 35, or never experiencing a full-term pregnancy.
  • Obesity refers to carrying excess weight.

Complications

Epithelial Ovarian Cancer (EOC) can lead to several complications, mainly if not diagnosed and treated early. Some of the main complications include:

  • Metastasis
  • Bowel Obstruction
  • Ascites
  • Peritonitis
  • Recurrent Cancer
  • Reduced Fertility
  • Anemia
  • Lymphedema

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Latest Research and Technologies in the Treatment of Epithelial Ovarian Cancer in Turkey

Turkey actively participates in international clinical trials and uses cutting-edge medicines, despite the lack of detailed data on the most recent research and technology for treating epithelial ovarian cancer in the nation. The creation of PARP inhibitors and anti-angiogenic medicines are recent developments on a global scale that have demonstrated promise in enhancing patient outcomes. Furthermore, novel strategies like CAR-NK cell therapy are being investigated to improve the effectiveness of treatment.

Epithelial Ovarian Cancer Prevention Tips

Some epithelial ovarian cancer prevention tips:

  • Long-term usage of hormonal birth control may lower the risk.
  • Prophylactic Surgery: High-risk individuals should consider having their ovaries and fallopian tubes removed.
  • Gynecological checks should be performed regularly to detect problems early on.
  • Healthy Diet: Eat a well-balanced diet high in fruits and vegetables.
  • Maintaining a healthy weight reduces the risk of ovarian cancer.
  • Avoid long-term hormone replacement therapy after menopause.
  • Exercise: Engaging in regular physical activity may reduce risk.
  • Breastfeeding may help reduce the risk of ovarian cancer.
  • Seek medical advice if you experience persistent symptoms such as bloating or abdominal pain.

Treatment options for Epithelial Ovarian Cancer

Surgery: Surgery for ovarian cancer may involve removing one or both ovaries, the fallopian tubes, or the uterus. For advanced cancer, surgery may be recommended, with chemotherapy administered before or after surgery.


Cost Start From USD 5000 - USD 27000Explore Options

Chemotherapy: Chemotherapy is a pharmacological treatment that uses chemicals to kill rapidly developing cells in the body, including cancer cells.


Cost Start From USD 7420 - USD 30000Explore Options

Targeted therapy: Targeted medication treatments target specific flaws seen in cancer cells. Targeted pharmacological treatments can potentially kill cancer cells by exploiting their weaknesses.


Cost Start From USD 7500 - USD 12000Explore Options

Hormone Therapy: Hormone therapy employs medications to inhibit the effects of the hormone estrogen on ovarian cancer cells. Some ovarian cancer cells need estrogen to develop; therefore, inhibiting estrogen may help control the malignancy.


Cost Start From USD 300 - USD 4000Explore Options

Immunotherapy: Immunotherapy utilises the immune system to combat cancer. The body's disease-fighting immune system may not attack cancer cells because they create proteins that allow them to hide from immune system cells. Immunotherapy works by interfering with the process.


Cost Start From USD 7420 - USD 42500Explore Options

Radiation therapy: Radiation therapy uses high-energy X-ray photons to eliminate cancer cells.

The following tests and procedures diagnose ovarian cancer:

Pelvic examination: During a pelvic exam, your doctor inserts gloved fingers into your vagina while pressing one hand on your belly to palpate your pelvic organs. The doctor will also visually inspect your external genitalia, vagina, and cervix.

Imaging testing: Ultrasound or CT scans of the abdomen and pelvis can assist in identifying the size, shape, and structure of your ovaries.

Blood testing: Blood testing may include organ function tests, which can assist in determining your overall health.

Genetic testing: Your doctor may recommend that you get a blood sample tested for gene mutations that raise your risk of developing ovarian cancer.

MediRehab (a chain of Rehab centres, part of MediGence) provides comprehensive rehabilitation services to support patients through Teleconsulations and online therapy sessions.

Physical therap
It can help you manage fatigue, increase mobility, and restore strength following surgery or chemotherapy.

Psychosocial Support
Psychosocial assistance includes counseling and support groups for anxiety, sadness, and emotional well-being before and after treatment.

Lymphedema Therapy
If necessary, treat fluid buildup that may develop following surgery or lymph node excision.

Depending on the circumstances, your doctor may prescribe medication to assist you in managing your symptoms and support your treatment plan.

Treatment regimens are adapted to the patient's specific cancer stage and location.

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Hospitals for Epithelial Ovarian Cancer in Turkey

Florence Nightingale Hospital: Top Doctors, and Reviews
Florence Nightingale Hospital

Istanbul, Turkey

The first green hospital in Turkey, Istanbul Florence Nightingale Hospital, was inaugurated in 2013. Group The Florence Nightingale hospitals are the first Turkish hospitals to be granted Joint Commission International (JCI) accreditation, and they continue to be associated and work with esteemed healthcare organizations.

The Florence Nightingale Group treats 250,000 outpatients and 70,000 inpatients annually, demonstrating its excellence. The hospitals have a capacity of 804 inpatient beds, 141 ICU beds, and 40 operating rooms, and perform 20,000+ procedures annually, of which 1,000 are cardiac operations for children and 2,000 are for adults. For conducting difficult orthopedic, general surgery, minimally invasive, and other heart treatments, the facility stands out. All operating rooms can be interconnected by audio-visual to a 300-person conference room and global hubs, enabling interactive medical teaching and scientific activity.

Interpreter and translator services for languages such as Turkish, Azerbaijani, Bulgarian, Arabic, English, Persian, Serbian, Russian, Albanian, Macedonian, German, Bosnian, and Romanian are available.

The hospital has specialized departments such as Cardiology and Cardiac Surgery, IVF and Infertility, Nephrology, Oncology and Oncosurgery, Spine Surgery, Neurology and Neurosurgery, Orthopedics, Gynecology, and Obesity or Bariatric Surgery. With an extensively qualified and experienced team of advisors and interpreters, Florence Nightingale Istanbul is committed to providing one-stop service from beginning to end, 24 hours a day, 7 days a week.

Medipol Bahçelievler Hospital: Top Doctors, and Reviews
Medipol Bahçelievler Hospital

Istanbul, Turkey

Medipol Bahcelievler Hospital is a medical institution providing a full range of medical and individualized approaches to its patients. Medipol has the ambition to bring high quality and maximum security to people in need by employing state-of-the-art technologies in medicine. They ensure that the health of the patients is improved by fashioning unique physician specialty treatment programs.

Medipol Bahcelievler Hospital provides an exceptional position in the healthcare industry with a policy of clear communication, professionalism, and reliability to patient expectations. Medipol Bahçelievler Hospital is situated in the European Side of Istanbul, dedicated to 24-hour health care for you and your loved ones, equipped with a fully functional operation theatre and ICUs with state-of-the-art equipment, laboratory, emergency, and advanced treatment rooms

Acibadem Altunizade Hospital: Top Doctors, and Reviews
Acibadem Altunizade Hospital

Istanbul, Turkey

Acibadem Altunizade Hospital located in Istanbul, Turkey is accredited by JCI. Also listed below are some of the most prominent infrastructural details:

  • The indoor area of Acibadem Hastanesi - Altunizade, Istanbul, Turkey is one of the largest at 98,000 square meters.
  • There are 550 beds and as many parking spots.
  • 75 of the beds are in the intensive care unit.
  • A hybrid operating room which has 3 diagnostic units at one location which is an amazing concept as at one time surgeries can be performed in 3 operating theatres.
  • International patients are serviced well through a particular center for them where services related to therapy and diagnostics are done.
  • Healthcare delivery in this part of the hospital can be availed in 16 different languages.
  • Robotic Surgery and Cell Therapy Unit are representative of the high standards of technology present in the hospital.

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Why Choose Turkey for Epithelial Ovarian Cancer Treatment?

Here are some of the reasons for choosing Turkey:

  • Due to advancements in medical facilities, such as minimally invasive surgical techniques.
  • World-class experts include highly experienced doctors and JCI-accredited healthcare institutions.
  • Compared to other countries, treatment in Turkish hospitals is cost-effective.
  • Turkish hospitals provide International patient services, including a multilingual support system.
  • Improved treatment methods and biological therapies.

Frequently Asked Questions

The 5-year relative survival rate for ovarian cancer in Turkey is roughly 50%, with considerable variation depending on the stage of the disease at diagnosis.

In Turkey, genetic testing is essential for ovarian cancer detection since it can identify BRCA mutations that affect treatment choices and risk. Early detection, individualised treatment, and educating family members about any genetic risks are all facilitated by it.

Regular follow-up care is critical for monitoring for cancer recurrence, managing treatment side effects, and maintaining overall health. This usually includes regular exams, imaging, and blood testing.

Early signs may be vague and easily missed, but they may include abdominal bloating, pelvic pain or pressure, changes in bowel habits, increased urine urgency, and unexplained weight loss. These symptoms may intensify as the condition progresses.

Yes, immunotherapy is a viable treatment option for ovarian cancer in Turkey, and top hospitals use it as part of their treatment regimens.

Turkey is a cost-effective choice for those seeking treatment because it provides top-notch medical care at affordable costs compared to several Western nations.

Yes, Turkey's healthcare system accepts patients from abroad and provides excellent EOC treatments at many clinics and hospitals.

Yes, many Turkish hospitals offer in-person and online consultations to foreign patients who want a second opinion.