Choledocholithiasis is the presence of one or more gallstones in the common bile duct (CBD). These stones may form in the gallbladder and migrate into the bile duct or, less commonly, develop directly within the bile ducts. A blocked bile duct can interfere with bile flow and may lead to jaundice, cholangitis or pancreatitis.
Timely diagnosis and treatment can help relieve bile duct obstruction and reduce the risk of complications such as acute cholangitis, obstructive jaundice and gallstone pancreatitis. When bile duct stones are confirmed, stone removal is generally recommended for patients who are fit to undergo treatment.
Causes
Risk Factors
Advances in the treatment of choledocholithiasis (bile duct stones) include improved diagnostic imaging, endoscopic retrograde cholangiopancreatography (ERCP), and specialised techniques for removing large or difficult stones. Magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasound (EUS) can help detect stones when initial imaging is inconclusive. During ERCP, techniques such as large-balloon dilation and cholangioscopy-guided laser or electrohydraulic lithotripsy can help remove complex stones. In Malaysia, the availability of advanced endoscopic procedures varies by hospital and specialist expertise. Early treatment is important when stones cause bile duct obstruction or infection.
ERCP with stone extraction : A minimally invasive procedure used to access the bile duct and remove stones.
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Endoscopic sphincterotomy: The opening of the bile duct may be carefully enlarged to facilitate stone removal.
Balloon dilation: Large-balloon dilation may be used with sphincterotomy for selected large or difficult stones.
Cholangioscopy-guided lithotripsy: Laser or electrohydraulic energy can fragment difficult stones before extraction.
Laparoscopic cholecystectomy: Removal of the gallbladder is generally considered when gallstones are the underlying source, helping reduce recurrent biliary events.
Biliary stenting: A temporary stent may be placed when stones cannot be removed immediately, and biliary drainage is required.









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