Manipal Hospitals have a dedicated Tumour Board to ensure excellent treatment for the patients. The medical oncology department at the Manipal Hospital involves various types of treatment therapies through medication including chemotherapy, biological therapy, bone marrow aspiration, and transplant among others. Radiation therapy to treat cancer is non-invasive.

The technologies at Manipal Hospital include Two Linear accelerators – Elekta Precise and Elekta Infinity along with a Gamma med brachytherapy system, Image-Guided Radio Therapy (IGRT) with onboard Cone Beam CT (CBCT), Volumetric Modulated Arc Therapy (VMAT), Intensity Modulated Radio Therapy (IMRT), Stereotactic Body Radio Therapy (SBRT), Stereotactic Radio Surgery (SRS) - Flattening filter-free- faster SRS delivery (FFF), Electrons for superficial tumors - 3 Dimensional Conformal Radio Therapy (3DCRT), 2 Dimensional Palliative Radio Therapy, Smart arc, and dynamic treatment planning, Brachyvision planning for brachytherapy, Image-guided brachytherapy. Manipal hospital also offers palliative care, child life care, a play therapy clinic, and counseling to patients suffering from kidney cancer.