Dr. Nick Plowman

• Dr Nick Plowman trained at Cambridge University, where he was a senior scholar with a Double First in Medical Sciences and Natural Sciences. He later returned to Cambridge to write his thesis on macrophages and lung cancer.
• He specialised in Oncology at St Bartholomew's Hospital, focusing on research and clinical development, and is now serving as a Senior Oncologist at Barts Health NHS Trust.
• He introduced aromatase inhibitors into breast cancer treatment, transforming the standard of care for breast cancer over the last 25 years.
• He pioneered the use of adrenosuppressive glucocorticoids for advanced prostate cancer, establishing new standards in hormonal therapy.
• His team continues active research on androgen signalling in prostate cancer, with implications for triple-negative breast cancer.
• He has been a pioneer in stereotactic radiation therapy ("radiosurgery"), publishing over 20 papers in the British Journal of Neurosurgery on its applications for brain tumours and metastases.
• For the last 20 years, his team has researched DNA repair mechanisms, leading to the discovery of two new DNA repair fault diseases with significant implications for cancer genomics.
• He is actively involved with genomics companies, advising on personalised cancer therapies, liquid biopsy, and predictive testing for optimised cancer treatment.
• His Oncology Clinic at 20 Harley Street specialises in advanced cancer genomics and collaborates with top specialists across various oncology disciplines.
• He served as principal investigator on the landmark trial showing that chemo-radiotherapy can cure many anorectal cancers without surgery.
• He introduced radiation seed brachytherapy for early prostate cancer to The London Clinic in 2020, offering a non-surgical option for selected patients.

Conditions treated by Dr. Nick Plowman

• Flexible sigmoidoscopy
• Breast cancer typing
• Prostate cancer
• Breast cancer
• Pancreatic cancer
• Lung cancer
• Colorectal cancer
• B-cell lymphoma
• Head and neck cancer

Area of Interest

• Oncology

Qualification

• Honours in Medicine, 1st Class, Cambridge University (1971)
• MA in Medicine, Guy’s Hospital
• MD in Medicine, Guy’s Hospital
• FRCP (Fellow of the Royal College of Physicians)
• FRCR (Fellow of the Royal College of Radiologists)

Work Experiences

• Dr Nick Plowman served as Consultant Clinical Oncologist at St Bartholomew’s Hospital and at the Hospital for Sick Children, Great Ormond Street.
• Dr Plowman worked as Head of Clinical Oncology (Radiation + Medical Oncology) at St Bartholomew’s Hospital since the late 1980s onward.
• He is recognised for leadership in introducing key therapies and radiotherapy techniques, including aromatase inhibitors for breast cancer, adrenosuppressive glucocorticoids for prostate cancer, chemo-radiotherapy for anal cancer, and pioneering radiotherapy technology such as Gamma Knife and CyberKnife.