Dr. Mohit Sharma

Dr. Mohit Sharma

Cancer Specialist - Medical Oncologist,Surgical Oncologist

  Venkateshwar Hospital, Delhi, India

  14 Years of experience

BIOGRAPHY

Dr. Mohit Sharma is one of the finest Cancer Specialist in India. He is an experienced Medical Oncologist in the India. The Medical practitioner has been associated with various reputed hospitals in the India. The physician is currently working as a Sr. Consultant - Medical Oncology, Venkateshwar Hospital, India. The doctor is a well-reputed and sought after medical expert and is

  • MBBS and MD - Government Medical College, Jammu
  • Training Medical Oncology - VMMC and Safdarjung Hospital, New Delhi
  • Post-doctoral Fellowship - Tata Memorial Hospital, Mumbai

qualified. Dr. Mohit Sharma has been associated with many hospitals over the course of his illustrious and experienced career.

The hospitals include:

  • Consultant (In-charge) - Medical Oncology at Columbia Asia Hospital, Palam Vihar, Gurgaon
  • Consultant (In-charge) - Medical Oncology at Fortis Escorts Hospital, Faridabad
  • Associate Consultant – Medical Oncology at Fortis memorial Research Institute, Gurgaon
  • Sr. Registrar – Medical Oncology at Tata Memorial Hospital, Mumbai
  • Sr. Resident – Medical Oncology at VMCC & Safdarjung Hospital, New Delhi

Dr. Mohit Sharma has more than 14 Years of clinic experience. The Clinician specializes in and performs the following surgeries:

  • Chemotherapy
  • Lung Cancer Treatment
  • Oncology
RESEARCH PAPERS AND PUBLICATIONS (1)
  • Various research articles and papers submitted in international and national journals.
Procedures
Chemotherapy

Chemotherapy is a category of standardized drug administration of various types for the treatment of cancer. With a curative intent, some combinations of drugs are administered to a patient to prolong their life and also to bring about a reduction in the symptoms shown by the patient. Chemotherapy treatment is considered to be one of the major categories of medical oncology. Many people around the world are prescribed to undergo chemotherapy treatment instead of undergoing a surgical procedure. But many are frightened with the side effects of this treatment as it is believed to reduce the quality of life of the patients.

What is chemotherapy?

Chemotherapy is a procedure where non-specific intracellular poisons are used, which are specifically related to preventing the process of mitosis or the natural cell division of the cancerous cells. This technique rather excludes those agents that are responsible for selective extracellular growth signal blockade (signal transduction blockers). If spoken about these agents used in chemotherapy, it has been found that most of them are cytotoxic in nature due to their property of interfering with natural mitosis. However, the cells of cancer can differ widely in terms of showing susceptibility to these administered agents.

Chemotherapy can be defined as a way of mass destruction of stress cells, which would eventually lead to the death of the cells when apoptosis is initiated. The commonly known side effects of chemotherapy can be traced back to the process of damaging normal non-cancerous cells, which are in the process of rapid division. They are sensitive to anti-mitotic drugs that are being administered to the patient and such cells may include the cells of the hair follicles, digestive tract lining, and bone marrow. But nowadays treatment options have undergone a lot of modification by which these side effects can be well countered.

Types of Chemotherapy Drugs

Various options of drugs are available to treat different types of cancer including the following:

Alkylating agents: These kinds of agents prove to be extremely beneficial during the cell’s resting phase. The various kinds of alkylating agents that are employed in chemotherapy treatment include the following:

  • Mustard gas derivatives: Cyclophosphamide, mechlorethamine, chlorambucil, ifosfamide, melphalan
  • Ethylenimines: Thiotepa and hexamethylmelamine
  • Alkylsulfonates: Busulfan
  • Metal salts: Oxaliplatin, cisplatin, and carboplatin
  • Nitrosoureas: Streptozocin, lomustine, carmustine

Nitrosoureas are unique from the rest for choices in chemotherapy treatment due to their ability to cross the blood-brain barrier and treating tumors of the brain.

Plant alkaloids: Plant alkaloids employed for chemotherapy treatment are derived from plants.  These include vinca alkaloids, taxanes, podophyllotoxins, and camptothecan analogs. The plant alkaloids are cell cycle specific agents, which enables them to attack the dividing cells in various stages of their division cycle.

Antimetabolites: This kind of chemotherapy treatment involves substances that are similar in composition to the normal substances present in the cell. When these substances get incorporated in the process of cellular metabolism, then the cell is no longer able to divide. They are also cell cycle specific and can be classified further according to the substance in the cell with which they interfere.

Topoisomerase inhibitors: When the topoisomerase enzymes in the body ( topoisomerase I and II) are inhibited as a result of chemotherapy drugs, then those drugs are referred to as topoisomerase inhibitors. During the chemotherapy, the topoisomerase enzymes are responsible for controlling structural manipulation of the DNA which is necessary for the purpose of replication.

Miscellaneous antineoplastics: Different types of drugs make each chemotherapy treatment process unique. Enzymes, retinoids, adrenocortical steroid inhibitor, ribonucleotide reductase inhibitor or antimicrotubule agents can be used as chemotherapy drugs.

Lung Cancer Treatment

Lung cancer is an uncontrolled growth of cells that start off in the lungs. Usually, lung cancer starts in the cells that line the air passages. Instead of developing into healthy lung tissue, the cells divide rapidly and form tumours.

Lung cancer can grow and spread beyond the lung to reach other parts of the body through metastasis. Lung cancers can begin in any part of the lung, but 90 percent of lung cancers begin in the epithelial cells, which are the cells lining the larger and smaller airways also known as bronchi and bronchioles.

This is the reason why lung cancers are sometimes called bronchogenic cancers or bronchogenic carcinomas. Lung cancer is the most common cancer in the world, among both men and women. It is the leading cause of cancer deaths worldwide.

Lung Cancer: Causes and Risk Factors

Long-term smoking is the main cause of lung cancer. After smoking, genetic factors and exposure to radon gas, asbestos, second-hand smoke or other forms of air pollution can also increase the risk of lung cancer.

Types of Lung Cancer

There are two major types of lung cancers, based on the appearance of lung cancer cells under the microscope:

  • Non-small cell lung cancer (NSCLC): It is an umbrella term for several types of lung cancers that behave in a similar way, such as squamous cell carcinoma, adenocarcinoma, and large cell carcinoma.
  • Small cell lung cancer (SCLC): This type of lung cancer occurs mostly in heavy smokers and it is less common than non-small cell lung cancer. 

Lung Cancer Stages

It is necessary to determine the stage of lung cancer by finding out how far cancer has spread, before initiating treatment of lung cancer.
The following are the four lung cancer stages of NSCLC:

  • Stage 1 lung cancer: Cancer is restricted to the lung
  • Stage 2 lung cancer: Cancer has spread to the nearby lymph nodes
  • Stage 3 lung cancer: (3a) Cancer is in the lung and the lymph nodes located on the same side  (3b) Cancer is in the lung and has spread to lymph nodes on the opposite side
  • Stage 4 lung cancer: Cancer has spread to both the lungs and other organs and surrounding tissues

The following are the two lung cancer stages of SCLC:

  • Limited stage: Cancer is present in just one lung and lymph nodes on the same side of cancer.
  • Extensive stage: Cancer has spread throughout the lung or both the lungs, to the lymph nodes on the opposite side, to the bone marrow, and to the distant organs.

After the determination of stage, treatment of lung cancer starts with choosing the best suitable option for the patient. However, there is usually no single treatment for lung cancer. So the patient often receives a combination of therapies and palliative care. 

Lung Cancer Symptoms

Lung cancer symptoms may vary, depending upon where and how widespread the tumour is. A person with lung cancer may have following lung cancer symptoms:

  • A persistent or chronic coughing
  • Pain in chest, shoulder or back
  • Difficulty in breathing and shortness of breath
  • Hoarseness or change of voice
  • Chronic bronchitis, pneumonia or respiratory infections
  • Blood in the sputum and cough


Stage 3 lung cancer symptoms include the following:

  • Wheezing
  • General pain in the chest or when breathing
  • Persistent cough with or without blood
  • Altered voice
  • Loss of appetite
  • Unplanned weight loss
  • Fever, headache, weakness, and bone pain
  • Difficulty swallowing
Frequently Asked Questions
What area of specialization does Dr. Mohit Sharma have?
Dr. Mohit Sharma is specialized in India and of the most sought after doctors in Cancer Specialist.
Does Dr. Mohit Sharma offer Telemedicine Consultation through Medigence?
No, this doctor dose not offer telemedicine via MediGence
How many years of experience does Dr. Mohit Sharma have?
Dr. Mohit Sharma is one of the most sought after specialists in India and has over 14 Years years of experience.
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