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Larynx Cancer Treatment: Symptoms, Classification, Diagnosis & Recovery

Laryngeal cancer is a type of cancer that affects the larynx, commonly known as the voice box. Symptoms of laryngeal cancer can include changes in the voice, such as hoarseness, and a persistent sore throat or cough. Treatment options may involve surgery to remove part or all of the larynx, by a procedure called a “laryngectomy”.

Cancer of the larynx or vocal cords occurs when cells in the larynx grow uncontrollably. As these malignant cells multiply, they invade surrounding tissues and cause damage to the body.

Laryngeal cancer can develop in any of the three main sections of the larynx:

  • Supraglottis (upper part): Over one-third (35%) of laryngeal cancers originate there.
  • Glottis (middle part): Most laryngeal cancers (60%) start here, where the vocal cords are located.
  • Subglottis (lower part): Approximately 5% of laryngeal cancers begin in this region.

Types:

Following are the types of larynx cancers:

  • Surgery with or without radiation therapy.
  • Radiation therapy.
  • Chemotherapy.
  • Immunotherapy with pembrolizumab or nivolumab.

Different stages of the laryngeal cancer are:

  • Early laryngeal cancer: In stages 0, 1, and 2, the tumor is small and has not spread beyond the larynx.
  • Advanced laryngeal cancer: In stages 3 and 4, the tumor has grown larger, affecting the vocal cords or spreading to the lymph nodes or other parts of the body.

When laryngeal cancer spreads beyond the larynx, it may invade the thyroid, windpipe (trachea), esophagus, tongue, lungs, liver, and bones.

Following are the signs and symptoms of larynx cancer:

  • cough or sore throat.
  • alterations in voice that don't go away after two weeks, like hoarseness.
  • discomfort or other problems while swallowing.
  • lump in your throat or neck.
  • difficulty producing vocal sounds (dysphonia).
  • Earache.

Here are some of the diagnostic tests that are used to detect larynx Cancer before the larynx cancer treatment:

  • Imaging scans such as CT or MRI scans provide detailed images of the inside of your body, showing the size and location of a tumor. A chest X-ray can determine if the cancer has spread to your lungs.
  • Laryngoscopy uses a thin, lighted tube called an endoscope to examine the larynx.
  • A PET scan is also performed by injecting a small, safe dose of a radioactive substance into your vein, which highlights areas with cancer cells.
  • A biopsy involves removing a small piece of abnormal tissue from the larynx for examination under a microscope. A pathologist will analyze the cells and look for specific protein markers, which can be crucial as some cancer treatments are effective only on cells with certain markers.

Recovery after laryngeal cancer treatment involves managing side effects and adjusting to changes in speech and swallowing. Rehabilitation may include speech therapy and dietary modifications to aid in recovery. Regular follow-up appointments are crucial for monitoring any recurrence of cancer and maintaining overall health.

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Author

Dr. Vishwas Kaushik
Dr. Vishwas Kaushik

MBBS, MD

7 Years of Experience

Dr. Vishwas Kaushik is a qualified medical professional holding an MBBS from the prestigious Belgorod State University, Russia, with a strong foundation in clinical medicine and healthcare practice. His comprehensive medical training has equipped him with a profound understanding of evidence-based clinical practices, patient-centered care, and the evolving landscape of modern medicine. With a keen interest in medical research and scientific communication, he consistently translates complex clinical concepts into clear, accurate, and accessible content for diverse audiences. His work reflects a deep commitment to advancing medical knowledge, delivering impactful healthcare insights, and bridging the gap between clinical expertise and accessible medical communication.. View More

Reviewer

Dr Prateek Varshney
Dr Prateek Varshney

Surgical Oncologist

15 Years of Experience

Dr. Prateek Varshney is a renowned Surgical Oncologist. He has experience of more than 15+ years in surgical Oncology. He is currently practicing as a consultant at Metro Mass Hospital and Cancer Institute. He was also previously associated as a consultant with Sir Ganga Ram Hospital and as a professor at Gujarat Cancer Research Institute. View More

Last Reviewed - January 2026