Peripheral vascular disease is a broad term used for conditions that affect the peripheral blood vessels, including arteries and veins. Peripheral arterial disease commonly occurs when atherosclerotic plaque narrows or blocks arteries, reducing blood flow to the limbs. Peripheral venous disease can occur when damaged or weakened veins struggle to return blood to the heart, causing swelling, heaviness, skin changes, or ulcers.
Timely evaluation helps determine whether symptoms stem from reduced arterial blood flow, venous circulation problems, blood clots, or another vascular condition. Appropriate treatment can help relieve symptoms, improve mobility, prevent wounds and tissue damage, and reduce the risk of serious complications. Sudden loss of blood flow to a limb or symptoms suggestive of a deep vein thrombosis or pulmonary embolism require urgent medical assessment.
Causes
Risk Factors
Compression Therapy: Compression stockings or bandages can help improve venous return and reduce swelling in selected patients with chronic venous disease and venous ulcers. Determine the appropriate compression level after assessing arterial circulation, particularly in patients who may also have PAD.
Radiofrequency Ablation (RFA) : This technique utilises high-frequency radiofrequency energy delivered via a specialised catheter to heat, damage, and permanently fibrose the inner vein lining.
Sclerotherapy : A doctor injects a specialised liquid or foamed chemical solution (sclerosant) directly into the target vein, causing the vessel walls to swell, stick together, and clot shut.
Microphlebectomy: A vascular specialist makes a series of tiny, millimetre-sized skin punctures and uses a micro-hook to physically pull out bulging, superficial veins piece by piece.
Thrombosis Treatment: Doctors usually treat DVT with anticoagulant medicines to prevent the clot from growing or causing complications. Selected patients with extensive or severe thrombosis may be considered for catheter-directed thrombolysis or thrombectomy.
Wound and Ulcer Care: Treatment depends on the wound's cause. Venous ulcers may require appropriate compression after arterial assessment, while arterial ulcers need blood supply evaluation and may require revascularisation. Wound care, infection management, and pressure relief may also be needed.
MediRehab (a chain of Rehab centres, part of MediGence) provides comprehensive tele-rehabilitation services to support patients with peripheral vascular disease in Malaysia. These services include:









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Interventional Cardiologist
29 Years of Experience
With a rich experience of more than 29 years, Dr. Nityanand has gained a vast spectrum of skills and expertise in performing all types of complex cardiac procedures. He is an expert in clinical & interventional cardiology and electrophysiology. He studied his medicine (MBBS) and MD from the Institute of Medical Sciences of Banaras Hindu University, Varanasi, and later completed his DM in Cardiology from the prestigious King George Medical University, Lucknow. View More
Last Reviewed - January 2026