Sheba Medical Center offers advanced Castleman Disease Treatment using modern diagnostic and therapeutic approaches and internationally accepted treatment protocols. Established in 1948, the JCI accredited hospital is located in Ramat Gan, Israel, with 1900 beds, providing comprehensive care for local and international patients.

Treatment depends on the type of Castleman disease, number of affected lymph node regions, symptoms, and associated conditions. Localised unicentric disease may often be treated with surgical removal of the affected lymph node, while multicentric disease may require medicines such as immunotherapy, corticosteroids, or other systemic treatments. Detailed evaluation helps determine the appropriate approach.