At Medipol Mega University Hospital, Nissen Fundoplication is performed using specialized anti-reflux and minimally invasive surgical techniques with comprehensive preoperative evaluation. Established in 2012, this JCI accredited hospital in Istanbul, Turkey has 810 beds and offers advanced gastroenterology, foregut surgery, and laparoscopic treatment services.

Nissen Fundoplication may be considered for patients with persistent or severe GERD symptoms despite appropriate medical management, selected patients with significant hiatal hernia, or those who prefer a surgical approach after specialist evaluation. Before surgery, the patient may undergo upper gastrointestinal endoscopy, esophageal manometry, pH monitoring, and imaging to confirm the diagnosis and assess esophageal function. During the procedure, the stomach fundus is wrapped 360 degrees around the lower esophagus to strengthen the anti-reflux barrier.