IRCCS Ospedale San Raffaele offers specialised Castleman Disease Treatment using modern diagnostic technology and established haematology treatment protocols. Established in 1971, the SSN accredited hospital is situated in milan, Italy, with 1350 beds, serving local and international patients.

Treatment is personalised according to the disease subtype, extent, symptoms, and underlying cause. Surgery may be recommended for unicentric disease when the affected lymph node can be safely removed, while multicentric forms may require targeted immunotherapy or other systemic medicines. Before treatment, the multidisciplinary team conducts imaging, lymph-node evaluation, blood tests, and other investigations to develop an appropriate treatment plan.