Advanced imaging techniques provide clinicians with the ability to evaluate the size, number, location, and origin of metastatic brain tumors before determining the effect they have on neurological function. Current imaging modalities, including contrast-enhanced MRI, PET-CT, and stereotactic biopsy, allow for optimal treatment planning. Early detection enables timely treatment options, including surgery, radiation therapy, targeted therapy, immunotherapy, or chemotherapy. Multidisciplinary treatment for cancer and neuro-oncology is associated with better outcomes and improved quality of life.