Whether working to find stones in the bile ducts and evaluating the severity of the infection so that complications like sepsis and liver damage do not occur, advanced imaging techniques and evaluations guide diagnosis and treatment. Diagnosis made early supports the use of antibiotics or drainage of the infected area through endoscopic techniques or by means of surgery. Working in a multidisciplinary fashion by involving gastroenterologist, hepatobiliary surgeons, radiologists, etc. has been shown to improve both the safety and outcomes of the patient.